2-Laurylamino-5-nitrothiazol | 64724-80-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 2-Laurylamino-5-nitrothiazol
• 英文别名: N-(5-nitro-thiazol-2-yl)-lauramide；N-(5-Nitro-thiazol-2-yl)-lauramid；N-(5-nitro-1,3-thiazol-2-yl)dodecanamide
• CAS: 64724-80-7
• 化学式: C₁₅H₂₅N₃O₃S
• 分子量: 327.448
• InChiKey: DZKKRHBAMGNRCD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.5
• 重原子数：
  22
• 可旋转键数：
  11
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.73
• 拓扑面积：
  116
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• Lipophilic drug compositions
  申请人：——

  公开号：US20030108596A1

  公开（公告）日：2003-06-12

  The invention is directed to biologically active lipophilic compositions comprising a biologically active covalently attached to, or encapsulated within, a lipid. Preferably, a biologically active agent is both covalently attached to a lipid and encapsulated within a lipid composition. Preferred lipid components include triglycerides and fatty acids. The resulting composition is preferably adapted for oral administration.

  本发明涉及具有生物活性的亲脂性组合物，该组合物包含共价连接到脂质上或封装在脂质中的生物活性物质。最好是生物活性剂既共价连接到脂质上，又封装在脂质组合物中。首选的脂质成分包括甘油三酯和脂肪酸。所得组合物最好适合口服。
• LIPOPHILIC DRUG COMPOSITIONS
  申请人：Sung, Michael T.

  公开号：EP1420828B1

  公开（公告）日：2012-09-26
• US7125568B2
  申请人：——

  公开号：US7125568B2

  公开（公告）日：2006-10-24
• US7390506B2
  申请人：——

  公开号：US7390506B2

  公开（公告）日：2008-06-24
• [EN] LIPOPHILIC DRUG COMPOSITIONS<br/>[FR] COMPOSITIONS DE MEDICAMENTS LIPOPHILES
  申请人：SUNG MICHAEL T

  公开号：WO2003018064A2

  公开（公告）日：2003-03-06

  The invention is directed to biologically active lipophilic compositions comprising a biologically active covalently attached to, or encapsulated within, a lipid. Preferably, a biologically active agent is both covalently attached to a lipid and encapsulated within a lipid composition. Preferred lipid components include triglycerides and fatty acids. The resulting composition is preferably adapted for oral administration.