2,3,3-trimethyl-butane-2-thiol | 38372-73-5

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醇
• 英文名称: 2,3,3-trimethyl-butane-2-thiol
• 英文别名: 2,3,3-Trimethylbutane-2-thiol；2,3,3-trimethylbutane-2-thiol
• CAS: 38372-73-5
• 化学式: C₇H₁₆S
• 分子量: 132.27
• InChiKey: DZOUOUCAVFGCBP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  8
• 可旋转键数：
  1
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  1
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  甲基碘化镁 、 thiopinacolone 以 乙醚 为溶剂， 生成 2,3,3-trimethyl-butane-2-thiol
  参考文献：
  名称：

  Paquer,D.; Vialle,J., Comptes Rendus des Seances de l'Academie des Sciences, Serie C: Sciences Chimiques, 1972, vol. 275, p. 589 - 592

  摘要：

  DOI：
• 作为试剂：
  描述：

  在 盐酸 、 sodium tetrahydroborate 、 cerium(III) chloride 、 2,3,3-trimethyl-butane-2-thiol 、 三正丁基氢锡 、 sodium hydride 、 calcium chloride 作用下， 以 甲醇 、 二甲基亚砜 为溶剂， 反应 5.0h， 生成 (1S,20R)-20-hydroxy-5,7-dioxa-14-azapentacyclo[12.7.0.01,17.02,10.04,8]henicosa-2,4(8),9,17-tetraen-15-one
  参考文献：
  名称：

  Total synthesis of the homoerythrinan alkaloids, schelhammericine and 3-epischelhammericine.

  摘要：

  这种立体控制的外消旋形式生物碱的全合成，是首次合成天然存在的同红花苷类生物碱。

  DOI：

  10.1248/cpb.33.3574

文献信息

• Nanocomposite silicon oxygen carbon materials and uses
  申请人：MELIOR INNOVATIONS, INC.

  公开号：US10633400B2

  公开（公告）日：2020-04-28

  Nanocomposite silicon and carbon compositions. These compositions can be made from polymer derived ceramics, and in particular, polysilocarb precursors. The nanocomposite can have non-voids or be nano-void free and can form larger macro-structures and macro-composite structures. The nanocomposite can contain free carbon domains in an amorphous SiOC matrix.

  纳米硅碳复合材料。这些组合物可以由聚合物衍生陶瓷，特别是聚硅碳前驱体制成。纳米复合材料可具有无空隙或无纳米空隙，并可形成较大的宏观结构和宏观复合结构。纳米复合材料可以在无定形 SiOC 基体中包含自由碳域。
• NANOCOMPOSITE SILICON OXYGEN CARBON MATERIALS AND USES
  申请人：MELIOR INNOVATIONS, INC.

  公开号：US20180065995A1

  公开（公告）日：2018-03-08

  Nanocomposite silicon and carbon compositions. These compositions can be made from polymer derived ceramics, and in particular, polysilocarb precursors. The nanocomposite can have non-voids or be nano-void free and can form larger macro-structures and macro-composite structures. The nanocomposite can contain free carbon domains in an amorphous SiOC matrix.
• Polysilocarb Materials, Methods and Uses
  申请人：Melior Innovations, Inc.

  公开号：US20190352464A1

  公开（公告）日：2019-11-21

  Polysilocarb formulations, cured and pyrolized materials, was well as articles and use for this material. In particular pyrolized polysilocarb ceramic materials and articles contain these materials where, the ceramic has from about 30 weight % to about 60 weight % silicon, from about 5 weight % to about 40 weight % oxygen, and from about 3 weight % to about 35 weight % carbon, and wherein 20 weight % to 80 weight % of the carbon is silicon-bound-carbon and 80 weight % to about 20 weight % of the carbon is free carbon.
• TRICYCLIC COMPOUNDS
  申请人：JACOBIO PHARMACEUTICALS CO., LTD.

  公开号：US20220119390A1

  公开（公告）日：2022-04-21

  Disclosed are tricyclic compounds as bromodomain and extra-terminal (BET) inhibitors which are shown as formula I, their synthesis and their use for treating diseases. More particularly, disclosed are fused heterocyclic derivatives useful as inhibitors of BET, methods for producing such compounds and methods for treating diseases and conditions wherein inhibition of one or more BET bromodomains provides a benefit.