Nonane-1,2,4-triol | 1269659-55-3

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: Nonane-1,2,4-triol
• 英文别名: nonane-1,2,4-triol
• CAS: 1269659-55-3
• 化学式: C₉H₂₀O₃
• 分子量: 176.256
• InChiKey: HKOJJYDRGLLZLY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  12
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  60.7
• 氢给体数：
  3
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  Nonane-1,2,4-triol 在 sodium periodate 、 4-甲基苯磺酸吡啶 作用下， 以 四氢呋喃 、 二氯甲烷 、 水 为溶剂， 反应 39.0h， 生成 2,2-dimethyl-4-pentyl-6-prop-2-enyl-1,3-dioxane
  参考文献：
  名称：

  FeCl3·6H2O-catalyzed synthesis of substituted cis-2,6-tetrahydropyrans from ζ-hydroxy allylic derivatives

  摘要：

  A highly diastereoselective iron-catalyzed synthesis of substituted cis-2,6-tetrahydropyrans from zeta-hydroxy allylic derivatives is described. The FeCl3 center dot 6H(2)O-induced epimerization of the formed 2-alkenyl 6-substituted tetrahydropyrans is the key reaction to account for the high diastereoselectivities observed. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2011.03.112
• 作为产物：
  描述：

  烯丙基正戊基甲醇 在 四氧化锇 、 N-甲基吗啉氧化物 作用下， 以 水 、 叔丁醇 为溶剂， 反应 3.0h， 生成 Nonane-1,2,4-triol
  参考文献：
  名称：

  FeCl3·6H2O-catalyzed synthesis of substituted cis-2,6-tetrahydropyrans from ζ-hydroxy allylic derivatives

  摘要：

  A highly diastereoselective iron-catalyzed synthesis of substituted cis-2,6-tetrahydropyrans from zeta-hydroxy allylic derivatives is described. The FeCl3 center dot 6H(2)O-induced epimerization of the formed 2-alkenyl 6-substituted tetrahydropyrans is the key reaction to account for the high diastereoselectivities observed. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2011.03.112

文献信息

• [EN] KETAL ESTERS OF OXOCARBOXYLIC ACIDS AND PROCESS OF MAKING<br/>[FR] ESTERS CÉTALS D'ACIDES OXOCARBOXYLIQUES ET PROCÉDÉ DE FABRICATION
  申请人：SEGETIS INC

  公开号：WO2011032095A1

  公开（公告）日：2011-03-17

  A ketal ester of an oxocarboxylic acid and a process to make the same, where the ketal ester is of Structure (I): wherein a is 0 or an integer from 1 to 12; n is 0 or 1; R1 is a linear alkyl, aryl, arylalkylene, or branched alkyl group with 1-18 carbon atoms; R2 and R5 can be hydrogen, C1-6 straight chain or branched alkyl, phenyl, substituted phenyl, C1-6 alkyl substituted with up to four OH groups, C1-6 alkyl, or acetyl optionally substituted hydrocarbon radicals, or R2 and R4 together with the α-carbon form a cycloaliphatic or heterocyclic ring with 3-6 carbon atoms and 0-3 heteroatoms, provided that only one of R2 and R5 is hydrogen; R3 is a linear alkyl or branched alkyl group with 1-18 carbon atoms; and R4 is hydrogen, or an alkyl, aryl, aralkyl or branched alkyl group with 1-10 carbon atoms.

  一种羰基羧酸的酯环氧乙烷缩合物及其制备方法，其中酯环氧乙烷缩合物具有以下结构（I）：其中a为0或1-12的整数；n为0或1；R1为1-18个碳原子的线性烷基、芳基、芳基烷基或支链烷基；R2和R5可以是氢、C1-6直链或支链烷基、苯基、取代苯基、C1-6烷基取代的带有最多四个羟基的烷基、C1-6烷基或乙酰基，也可以是R2和R4与α-碳共同形成含有3-6个碳原子和0-3个杂原子的环状脂肪族或杂环；但只有R2和R5中的一个是氢；R3为1-18个碳原子的线性烷基或支链烷基；R4为氢、或1-10个碳原子的烷基、芳基、芳基烷基或支链烷基。
• Polyketal Compounds, Synthesis, and Applications
  申请人：Selifonov Sergey

  公开号：US20110021658A1

  公开（公告）日：2011-01-27

  The invention relates to polyketal compounds. The compounds are synthesized by the selective ketalization of oxocarboxylic acids, e.g. keto acids and semialdehydes, and esters thereof with tetrols and higher polyols that products two or more cyclic ketal ester moieties per molecule, wherein the cyclic ketal moieties are situated in a bis-, tris-, or polyketal conformation. The invention further relates to applications of these compounds and subsequent reactions thereof.

  该发明涉及聚酯化合物。该化合物是通过选择性酮缩氧羧酸，例如酮酸和半醛，以及它们与四元醇和更高级聚醇的酯的缩酮化合成的，每个分子产生两个或更多的环状缩酮酯基团，其中环状缩酮基团位于双酯，三酯或聚酯构象中。该发明还涉及这些化合物及其后续反应的应用。
• POLYKETAL COMPOUNDS, SYNTHESIS, AND APPLICATIONS
  申请人：Segetis, Inc.

  公开号：EP2205606A2

  公开（公告）日：2010-07-14
• KETAL COMPOUNDS FROM POLYOLS AND OXOCARBOXYLATES
  申请人：Segetis, Inc.

  公开号：EP2185625A1

  公开（公告）日：2010-05-19
• Ketal Compounds from Polyols and Oxocarboxylates
  申请人：Wicks Douglas Alan

  公开号：US20110319586A1

  公开（公告）日：2011-12-29

  Novel ketal compounds can be made from an oxocarboxylate and a triol. Novel polymeric structures are, in turn, synthesized from the ketal compounds. Such ketal compounds and associated polymers are useful in a broad range of applications as a substitute for materials derived from petroleum or other such nonrenewable resources.