Methyl 3-methylimidazol-3-ium-1-carboxylate

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: Methyl 3-methylimidazol-3-ium-1-carboxylate
• 化学式: C6H9N2O2+
• 分子量: 141.15
• InChiKey: GVZGDNVHTOTGSQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.4
• 重原子数：
  10
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  35.1
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• DOUBLE-HEADED PROTEASE INHIBITOR
  申请人：UBE INDUSTRIES, LTD.

  公开号：US20200347011A1

  公开（公告）日：2020-11-05

  The present invention provides a compound that is highly safe and useful in the prevention, alleviation, and/or treatment of various diseases involving enteropeptidase inhibition and/or trypsin inhibition, a pharmaceutical composition containing the compound, a method for producing the compound, and the like. Specifically, the present invention provides a compound represented by the following general formula (I): [wherein: A 1 and A 2 each independently represent an inhibitor residue having at least one activity selected from an enteropeptidase inhibitory activity and a trypsin inhibitory activity; and Z represents a spacer that links A 1 to A 2 ] or a pharmaceutically acceptable salt thereof.