2-Morpholinbutan | 67061-36-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 恶嗪烷类
• 英文名称: 2-Morpholinbutan
• 英文别名: N-sek-Butylmorpholin；(+/-)-sec-Butylmorpholin；4-sec-butyl-morpholine；4-sec-Butyl-morpholin；N-(1-methyl-propyl)-morpholine；4-Sec-butylmorpholine；4-butan-2-ylmorpholine
• CAS: 67061-36-3
• 化学式: C₈H₁₇NO
• 分子量: 143.229
• InChiKey: FDHGUCPWMSEFHX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  10
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  12.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  4-(2-benzenesulfonyl-1-methyl-propyl)-morpholine 、 甲醇 以32%的产率得到
  参考文献：
  名称：

  DROZD V. N.; SERGEJCHUK V. V., ZH. ORGAN. XIMII, 1979, 15, HO 4, 730-735

  摘要：

  DOI：

文献信息

• Vanilloid receptor ligands, pharmaceutical compositions containing them, process for making them and use thereof for treating pain and other conditions
  申请人：Frank Robert

  公开号：US20080275044A1

  公开（公告）日：2008-11-06

  Compounds corresponding to formula I: which act as vanilloid receptor ligands, pharmaceutical compositions containing such compounds, a process for the producing such compounds, and the use thereof to treat or inhibit pain and/or various other disorders or conditions.

  与公式I对应的化合物：作为辣椒素受体配体的化合物，含有这种化合物的药物组合物，生产这种化合物的过程，以及利用它们治疗或抑制疼痛和/或其他多种疾病或症状的用途。
• METHOD FOR PRODUCING GLUCOSE BY ENZYMATIC HYDROLYSIS OF CELLULOSE THAT IS OBTAINED FROM MATERIAL CONTAINING LIGNO-CELLULOSE USING AN IONIC LIQUID THAT COMPRISES A POLYATOMIC ANION
  申请人：Balensiefer Tim

  公开号：US20100081798A1

  公开（公告）日：2010-04-01

  The present invention relates to a process for preparing glucose from a lignocellulose-comprising starting material, in which this is firstly treated with an ionic liquid and subsequently subjected to an enzymatic hydrolysis. The invention further relates to a process for preparing microbial metabolites, especially ethanol, in which the glucose obtained is additionally subjected to a fermentation.

  本发明涉及一种从含木质纤维素的起始物质制备葡萄糖的过程，首先将其与离子液体处理，然后经酶解处理。该发明还涉及一种制备微生物代谢产物，特别是乙醇的过程，其中所获得的葡萄糖额外经过发酵处理。
• ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH
  申请人：OssiFi Inc.

  公开号：US20140288068A1

  公开（公告）日：2014-09-25

  In one aspect, the invention provides compounds of Formula I, and salts, hydrates and isomers thereof. In another aspect, the invention provides a method of promoting bone formation in a subject in need thereof by administering to the subject a therapeutically effective amount of a compound of Formula I, Formula II, or Formula III. The present invention also provides orthopedic and periodontal devices, as well as methods for the treatment of renal disease and cancer, using a compound of Formula I, Formula II, or Formula III.

  在一个方面，该发明提供了式I的化合物，以及其盐、水合物和异构体。在另一个方面，该发明提供了一种通过向需要的受试者投予式I、式II或式III的化合物的治疗有效剂量来促进骨形成的方法。本发明还提供了骨科和牙周设备，以及使用式I、式II或式III的化合物治疗肾脏疾病和癌症的方法。
• PROCESS FOR PREPARING SILOXY CARBOXYLATES
  申请人：Gärtner Martin

  公开号：US20120157701A1

  公开（公告）日：2012-06-21

  A process for preparing siloxy carboxylates is characterized by reaction of C 2 -C 10 -monocarboxylic acids with halosiloxanes of the general formula (I), Hal-(SiR 2 —O) x —SiR 3 (I) in which Hal is the same or different and is fluorine, chlorine, bromine or iodine, R is hydrogen, C 1 -C 10 -alkyl or C 6 -C 14 -aryl and x is an integer from 1 to 20, to form hydrogen halide in the presence of an auxiliary base, in which the auxiliary base forms, with the hydrogen halide, a salt which forms two immiscible phases with the siloxy carboxylate or the solution of the siloxy carboxylate in a suitable solvent and is removed by a liquid-liquid separation. The process enables simple and economically viable preparation of siloxy carboxylates.

  一种制备硅氧羧酸酯的方法，其特征在于将C2-C10-单羧酸与一般式(I)的卤代硅氧烷发生反应，其中Hal-(SiR2—O)x—SiR3(I)，其中Hal是相同或不同的氟、氯、溴或碘，R是氢、C1-C10-烷基或C6-C14-芳基，x为1至20的整数，以形成氢卤素在辅助碱的存在下，其中辅助碱与氢卤素形成盐，与硅氧羧酸酯或硅氧羧酸酯在适当溶剂中的溶液形成两个不相溶的相，并通过液-液分离去除。该方法实现了硅氧羧酸酯的简单和经济可行的制备。
• Preparation of a Quinolinyloxydiphenylcyclopropanedicarboxamide
  申请人：Deschamps Nicole Marie

  公开号：US20100081805A1

  公开（公告）日：2010-04-01

  The present invention relates to a process of preparing a compound of the following formula III: wherein R 1 -R 4 are as defined herein. The present invention also relates to the preparation of intermediates used to prepare the compound of formula III

  本发明涉及一种制备以下化合物的方法：其中R1-R4如本文所定义。本发明还涉及用于制备化合物III的中间体的制备。

表征谱图