[(4-methoxyphenyl)ethynyl]{2-[(4-methoxyphenyl)ethynyl]phenyl}dimethylsilane | 922501-46-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: [(4-methoxyphenyl)ethynyl]{2-[(4-methoxyphenyl)ethynyl]phenyl}dimethylsilane
• 英文别名: 2-(4-Methoxyphenyl)ethynyl-[2-[2-(4-methoxyphenyl)ethynyl]phenyl]-dimethylsilane；2-(4-methoxyphenyl)ethynyl-[2-[2-(4-methoxyphenyl)ethynyl]phenyl]-dimethylsilane
• CAS: 922501-46-0
• 化学式: C₂₆H₂₄O₂Si
• 分子量: 396.561
• InChiKey: PCQMAJLOKPTVAJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.61
• 重原子数：
  29
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.15
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  [(4-methoxyphenyl)ethynyl]{2-[(4-methoxyphenyl)ethynyl]phenyl}dimethylsilane 、 1,4-二甲氧基-2-丁炔 在 bis(1,5-cyclooctadiene)diiridium(I) dichloride 、 三苯基膦 作用下， 以 二丁醚 为溶剂， 反应 24.0h， 以77%的产率得到2,3-bis(methoxymethyl)-1,4-bis(4-methoxyphenyl)-9,9-dimethyl-9-silafluorene
  参考文献：
  名称：

  Synthesis of Silafluorenes by Iridium-Catalyzed [2 + 2 + 2] Cycloaddition of Silicon-Bridged Diynes with Alkynes

  摘要：

  Silicon-bridged 1,6-diynes underwent [2 + 2 + 2] cycloaddition with alkynes in the presence of an iridium(I)-phosphine catalyst to afford densely substituted silafluorene derivatives. Extended silafluorene skeletons were constructed by the [2 + 2 + 2] cycloaddition of tetraynes.

  DOI：

  10.1021/ol062732n
• 作为产物：
  描述：

  4-(2-bromophenylethynyl)anisole 在 正丁基锂 作用下， 以 四氢呋喃 、 正己烷 为溶剂， 生成 [(4-methoxyphenyl)ethynyl]{2-[(4-methoxyphenyl)ethynyl]phenyl}dimethylsilane
  参考文献：
  名称：

  Synthesis of Silafluorenes by Iridium-Catalyzed [2 + 2 + 2] Cycloaddition of Silicon-Bridged Diynes with Alkynes

  摘要：

  Silicon-bridged 1,6-diynes underwent [2 + 2 + 2] cycloaddition with alkynes in the presence of an iridium(I)-phosphine catalyst to afford densely substituted silafluorene derivatives. Extended silafluorene skeletons were constructed by the [2 + 2 + 2] cycloaddition of tetraynes.

  DOI：

  10.1021/ol062732n

文献信息

• Synthesis of Silafluorenes by Iridium-Catalyzed [2 + 2 + 2] Cycloaddition of Silicon-Bridged Diynes with Alkynes
  作者：Takanori Matsuda、Sho Kadowaki、Tsuyoshi Goya、Masahiro Murakami

  DOI：10.1021/ol062732n

  日期：2007.1.1

  Silicon-bridged 1,6-diynes underwent [2 + 2 + 2] cycloaddition with alkynes in the presence of an iridium(I)-phosphine catalyst to afford densely substituted silafluorene derivatives. Extended silafluorene skeletons were constructed by the [2 + 2 + 2] cycloaddition of tetraynes.