3,6-bis[(4S)-4,5-dihydro-4-isopropyloxazol-2-yl]pyridazine | 352352-33-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: 3,6-bis[(4S)-4,5-dihydro-4-isopropyloxazol-2-yl]pyridazine
• 英文别名: (4S)-4-propan-2-yl-2-[6-[(4S)-4-propan-2-yl-4,5-dihydro-1,3-oxazol-2-yl]pyridazin-3-yl]-4,5-dihydro-1,3-oxazole
• CAS: 352352-33-1
• 化学式: C₁₆H₂₂N₄O₂
• 分子量: 302.376
• InChiKey: YIPHLHNYQGWJEF-ZIAGYGMSSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  22
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  69
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  六氟磷酸银 、 bis(η3-allyl-μ-chloropalladium(II)) 、 3,6-bis[(4S)-4,5-dihydro-4-isopropyloxazol-2-yl]pyridazine 以 二氯甲烷 为溶剂， 以100%的产率得到
  参考文献：
  名称：

  Synthesis and crystal structure of twisted dinuclear η3-allylpalladium complexes containing tetradentate nitrogen ligands

  摘要：

  The dinuclear palladium allyl complexes 7 and 12, which contain tetradentate nitrogen ligands 2 or 3 as bridging ligands, respectively, were synthesized and characterized. Crystal X-ray analysis of these complexes reveal that the two coordination planes of the palladium are twisted, although each of the coordination spheres presents roughly the same structural features as the related (bipyridine)allylpalladium complex. (C) 2001 Elsevier Science B.V. All rights reserved.

  DOI：

  10.1016/s0022-328x(01)00729-x
• 作为产物：
  描述：

  dimethyl pyridazine-3,6-dicarboxylate 在 正丁基锂 、 氯化亚砜 、 potassium tert-butylate 作用下， 以 四氢呋喃 、 二氯甲烷 为溶剂， 反应 25.5h， 生成 3,6-bis[(4S)-4,5-dihydro-4-isopropyloxazol-2-yl]pyridazine
  参考文献：
  名称：

  Synthesis and crystal structure of twisted dinuclear η3-allylpalladium complexes containing tetradentate nitrogen ligands

  摘要：

  The dinuclear palladium allyl complexes 7 and 12, which contain tetradentate nitrogen ligands 2 or 3 as bridging ligands, respectively, were synthesized and characterized. Crystal X-ray analysis of these complexes reveal that the two coordination planes of the palladium are twisted, although each of the coordination spheres presents roughly the same structural features as the related (bipyridine)allylpalladium complex. (C) 2001 Elsevier Science B.V. All rights reserved.

  DOI：

  10.1016/s0022-328x(01)00729-x

文献信息

• Synthesis and crystal structure of twisted dinuclear η3-allylpalladium complexes containing tetradentate nitrogen ligands
  作者：Naofumi Tsukada、Tetsuo Sato、Hiroyuki Mori、Shuichi Sugawara、Chizuko Kabuto、Sotaro Miyano、Yoshio Inoue

  DOI：10.1016/s0022-328x(01)00729-x

  日期：2001.5

  The dinuclear palladium allyl complexes 7 and 12, which contain tetradentate nitrogen ligands 2 or 3 as bridging ligands, respectively, were synthesized and characterized. Crystal X-ray analysis of these complexes reveal that the two coordination planes of the palladium are twisted, although each of the coordination spheres presents roughly the same structural features as the related (bipyridine)allylpalladium complex. (C) 2001 Elsevier Science B.V. All rights reserved.