N-十二烷基-2-甲基丙-2-烯酰胺 | 1191-39-5

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: N-十二烷基-2-甲基丙-2-烯酰胺
• 中文别名: N-十二烷基甲基
• 英文名称: N-dodecyl methacrylamide
• 英文别名: N-n-dodecylmethacrylamide；N-dodecylmethacrylamide；lauryl methacrylamide；dodecyl methacrylamide；LMAM；N-dodecyl-2-methylprop-2-enamide
• CAS: 1191-39-5
• 化学式: C₁₆H₃₁NO
• mdl: MFCD00048439
• 分子量: 253.428
• InChiKey: HOZLHJIPBBRFGM-UHFFFAOYSA-N

物化性质

• 沸点：
  145°C 0,8mm

计算性质

• 辛醇/水分配系数(LogP)：
  6.1
• 重原子数：
  18
• 可旋转键数：
  12
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.812
• 拓扑面积：
  29.1
• 氢给体数：
  1
• 氢受体数：
  1

安全信息

• 安全说明：
  S26,S36/37/39
• 危险类别码：
  R36/37/38
• 海关编码：
  2924199090

反应信息

• 作为产物：
  描述：

  在 吩噻嗪 作用下， 100.0 ℃ 、7.0 kPa 条件下， 反应 48.0h， 生成 N-十二烷基-2-甲基丙-2-烯酰胺
  参考文献：
  名称：

  Ｎ−置換（メタ）アクリルアミドの製造方法

  摘要：

  在温和条件下，提供高纯度的N-取代（甲基）丙烯酰胺的制备方法。通过在硅作为主要成分的催化剂存在下，进行氨基丙酸酰胺衍生物[1]的液相热分解，使胺化合物脱离，从而得到N-取代（甲基）丙烯酰胺[3]的方法。（R1〜R5代表H，C1〜32的烷基，羟基烷基等。）【选择图】无

  公开号：

  JP2015209419A

文献信息

• Copolymers Based on N-Vinylpyrrolidone and Branched Aliphatic Carbonxylic Acids, and Their Use as Solubilizers
  申请人：Angel Maximilian

  公开号：US20080200564A1

  公开（公告）日：2008-08-21

  Copolymers comprising: (a) 60 to 99% by weight of at least one monomer selected from the group consisting of N-vinyllactams, N-vinylamides, and mixtures thereof; (1) 1 to 40% by weight of at least one monomer selected from the group consisting of vinyl esters of aliphatic branched C 8 -C 30 -carboxylic acids; (c) 0 to 30% by weight of vinyl acetate; and (d) 0 to 39% by weight of at least one additional free-radically copolymnerizable monomer; wherein the % by weight content of components (a), (b), (c) and (d) totals 100%, and with the proviso that the total amount of component (b) and component (c) combined is 1 to 40% by weight based on the copolymer, are described along with methods of using such copolymers to solubilize substances which are insoluble in water, substances which are only sparingly soluble in water, and combinations thereof.

  共聚物包含：（a）60至99重量百分比的至少一种单体，选自N-乙烯基内酰胺、N-乙烯酰胺和它们的混合物；（b）1至40重量百分比的至少一种单体，选自支链的C8-C30脂肪族羧酸的乙烯酯；（c）0至30重量百分比的乙酸乙烯酯；和（d）0至39重量百分比的至少一种额外的自由基共聚单体；其中，组分（a）、（b）、（c）和（d）的重量百分比总和为100%，并且有条件规定组分（b）和组分（c）的总和基于共聚物为1至40重量百分比。还描述了使用这样的共聚物来增溶水不溶性物质、水微溶性物质以及它们的组合的方法。
• Personal care compositions comprising hydrophobically modified cationic polymers
  申请人：Carnali Oreste Joseph

  公开号：US20070259795A1

  公开（公告）日：2007-11-08

  The invention provides personal care/personal wash compositions comprising hydrophobically modified cationic polymers which enhance deposition of benefit agent.

  这项发明提供了含有疏水修饰阳离子聚合物的个人护理/洗涤组合物，可增强益处剂的沉积。
• A Fluorescent Polymeric Heparin Sensor
  作者：Wei Sun、Heinz Bandmann、Thomas Schrader

  DOI：10.1002/chem.200700677

  日期：2007.9.17

  glucosaminoglucans. Heparin can be quantitatively detected with an unprecedented 30 nM sensitivity, and a neutral polymer without any ammonium cation is still able to bind the target with almost micromolar affinity. From this unexpected result, we propose a new binding scheme between the boronate and a sulfated ethylene glycol or aminoethanol unit. Although the mechanism of heparin binding involves covalent

  已经开发出带有为硫酸糖量身定制的结合位点的线性共聚物。所有结合单体均基于甲基丙烯酰胺骨架，并确保统计自由基共聚。它们用邻氨基甲基苯基硼酸酯装饰以形成共价酯，和/或用烷基铵离子装饰以实现非共价库仑吸引。醇侧链保持较高的水溶性；丹磺酰基单体被构建为荧光标记。由AIBN（AIBN = 2,2'-偶氮异丁腈）开始以最佳比例进行共聚单体混合物的统计共聚，并提供了对葡糖氨基葡聚糖具有极高亲和力的水溶性共聚单体。肝素可以以前所未有的30 nM灵敏度进行定量检测，不含任何铵阳离子的中性聚合物仍然能够以几乎微摩尔的亲和力结合靶标。从这个出乎意料的结果来看，我们提出了硼酸酯与硫酸化乙二醇或氨基乙醇单元之间的新结合方案。尽管肝素结合的机制涉及共价硼酸酯的形成，但可以通过鱼精蛋白的添加完全逆转，类似于肝素与抗凝血酶III的复合物形成。
• COSMETIC COMPOSITION COMPRISING AT LEAST ONE CATIONIC COPOLYMER AND AT LEAST ONE ANIONIC ASSOCIATIVE POLYMER AND COSMETIC TREATMENT PROCESSES USING SAID COMPOSITION
  申请人：BIGANSKA Olga

  公开号：US20090074692A1

  公开（公告）日：2009-03-19

  The disclosure relates to novel cosmetic compositions comprising, in a cosmetically acceptable medium: (i) at least one cationic polymer which are produced by polymerization of a mixture of monomers comprising: a) at least one vinyl monomer substituted with at least one amino group, b) at least one hydrophobic nonionic vinyl monomer, c) at least one associative vinyl monomer, and e) at least one hydroxylated nonionic vinyl monomer, and (ii) at least one anionic associative polymers.

  该披露涉及新型化妆品组合物，包括在适合用于化妆的介质中的：(i) 至少一种阳离子聚合物，其由包括：a) 至少一种含有至少一个氨基团的乙烯单体，b) 至少一种疏水非离子乙烯单体，c) 至少一种关联性乙烯单体，和e) 至少一种羟基化非离子乙烯单体的单体混合物聚合而成，以及(ii) 至少一种阴离子关联性聚合物。
• Continuous Method for Producing Amides of Ethylenically Unsaturated Carboxylic Acids
  申请人：Krull Matthias

  公开号：US20110089020A1

  公开（公告）日：2011-04-21

  The invention relates to a continuous method for producing amides, according to which at least one carboxylic acid of formula (I) R 3 -COON (I), wherein R 3 is an optionally substituted alkenyl group comprising between 2 and 4 carbon atoms, is reacted with at least one amine of formula (II) HNR 1 R 2 (II), wherein R 1 and R 2 are independently hydrogen or a hydrocarbon radical comprising between 1 and 100 C atoms, to form an ammonium salt and/or a Michael adduct, and said ammonium salt is then reacted to form a carboxylic acid amide. under microwave irradiation in a reaction pipe, the longitudinal axis of the pipe being oriented in the direction of propagation of the microwaves of a monomode microwave applicator.

  该发明涉及一种连续生产酰胺的方法，根据该方法，至少一个具有化学式（I）R3-COON（I）的羧酸发生反应，其中R3是一个由2至4个碳原子组成的可选择取代的烯基基团，与至少一个具有化学式（II）HNR1R2（II）的胺发生反应，其中R1和R2独立地是氢或包含1至100个碳原子的烃基团，形成铵盐和/或迈克尔加合物，然后将所述铵盐反应形成羧酸酰胺，在微波辐射下在反应管内进行，管的纵轴朝向单模微波应用器的微波传播方向。