(+/-)-5t-chloro-1-phenyl-(3at,7at)-3a,4,5,6,7,7a-hexahydro-1H-4r,7c-methano-benzotriazole-5c-carboxylic acid methyl ester | 108838-63-7

• 分子结构分类: 有机化合物 - 有机杂环化合物
• 英文名称: (+/-)-5t-chloro-1-phenyl-(3at,7at)-3a,4,5,6,7,7a-hexahydro-1H-4r,7c-methano-benzotriazole-5c-carboxylic acid methyl ester
• 英文别名: (+/-)-5t-Chlor-1-phenyl-(3at,7at)-3a,4,5,6,7,7a-hexahydro-1H-4r,7c-methano-benzotriazol-5c-carbonsaeure-methylester
• CAS: 108838-63-7
• 化学式: C₁₅H₁₆ClN₃O₂
• 分子量: 305.764
• InChiKey: QOOKMVXBFFIMIJ-VWKSAYTASA-N

反应信息

• 作为产物：
  描述：

  重氮甲烷 、 叠氮苯 、 alkaline earth salt of/the/ methylsulfuric acid 生成 (+/-)-5t-chloro-1-phenyl-(3at,7at)-3a,4,5,6,7,7a-hexahydro-1H-4r,7c-methano-benzotriazole-5c-carboxylic acid methyl ester
  参考文献：
  名称：

  Genetic and Biogeographic Relationships of the Invasive Round (Neogobius melanostomus) and Tubenose (Proterorhinus marmoratus) Gobies in the Great Lakes Versus Eurasian Populations

  摘要：

  Population genetic structure and systematic relationships were investigated for two exotic fishes introduced to the Great Lakes in 1990, the round goby Neogobius melanostomus and the tubenose goby Proterorhinus marmoratus, using DNA sequences from the left domain of the mitochondrial DNA control region. Samples of round gobies were compared from different sites in the Great Lakes, an introduced population from the Gulf of Gdansk in Poland, and a native population from the northern Black Sea. The round goby was characterized by, relatively high genetic variability, and 17 haplotypes were identified from 64 individuals. Levels of genetic variation for the round goby were similar in the invasive and native sampling sites, suggesting relatively large founding populations and lack of bottlenecks. The northern Black Sea was eliminated as a probable founding source for both the Great Lakes and the exotic population in Poland. Substitutions in the left domain of the control region revealed significant differences among samples from the Great Lakes and Eurasia, and between Lakes Erie and St. Clair, suggesting non-random mating. No variation was detected in the tubenose goby population in the Great Lakes, which has been less successful in terms of spread and population growth. A molecular clock calibration suggested that the genera Neogobius and Proterorhinus diverged about 5.2 +/- 1.0 million years ago, apparently separating from a common ancestor shared with Gobius during the isolation of the Paratethys basin from the Mediterranean Tethys Sea.

  DOI：

  10.1016/s0380-1330(01)70642-9