O¹,O²-isopropylidene-3-(2,2,2-trifluoro-acetylamino)-α-D-ribo-3-deoxy-pentodiald-1,4-ose benzoylhydrazone | 39682-09-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: O¹,O²-isopropylidene-3-(2,2,2-trifluoro-acetylamino)-α-D-ribo-3-deoxy-pentodiald-1,4-ose benzoylhydrazone
• CAS: 39682-09-2
• 化学式: C₁₇H₁₈F₃N₃O₅
• 分子量: 401.342
• InChiKey: ARVDBSRGRJJVFZ-HKUMRIAESA-N

反应信息

• 作为反应物：
  描述：

  O¹,O²-isopropylidene-3-(2,2,2-trifluoro-acetylamino)-α-D-ribo-3-deoxy-pentodiald-1,4-ose benzoylhydrazone 在 碘 、 magnesium oxide 、 mercury(II) oxide 作用下， 生成 (4S)-O¹,O²-isopropylidene-4-(5-phenyl-[1,3,4]oxadiazol-2-yl)-3-(2,2,2-trifluoro-acetylamino)-α-D-3-deoxy-erythrofuranose
  参考文献：
  名称：

  Dérivés C-glycosyliques X. C-Nucléosides oxadiazoliques inversés. Communication préliminaire

  摘要：

  AbstractThe synthesis of «reversed» 1, 3, 4‐oxadiazolyl C‐nucleosides by treatment of alduronic chlorides with N‐benzoylamino‐triphenylphosphinimine or by oxidation of aldehydodialdose benzoylphenylhydrazones is described. One of these compounds is the first example of an «reversed» C‐amino‐nucleoside having a β‐heteroaryl‐ethylamino grouping, a structural unit whose introduction into a sugar molecule is interesting from a pharmacological standpoint.

  DOI：

  10.1002/hlca.19720550812