Trimethyl-[(1R,2S)-2-(2,4,6-trimethyl-phenyl)-cyclohexyloxyethynyl]-silane | 157358-05-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Trimethyl-[(1R,2S)-2-(2,4,6-trimethyl-phenyl)-cyclohexyloxyethynyl]-silane
• CAS: 157358-05-9
• 化学式: C₂₀H₃₀OSi
• 分子量: 314.543
• InChiKey: IWBHKETXFVWWNK-RTBURBONSA-N

物化性质

• 沸点：
  403.2±45.0 °C(predicted)
• 密度：
  0.96±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

反应信息

• 作为反应物：
  描述：

  dicobalt octacarbonyl 、 Trimethyl-[(1R,2S)-2-(2,4,6-trimethyl-phenyl)-cyclohexyloxyethynyl]-silane 以 正戊烷 为溶剂， 以88%的产率得到
  参考文献：
  名称：

  A convenient synthesis of hexacarbonyldicobalt complexes of chiral (non-racemic) terminal alkoxyacetylenes

  摘要：

  The hexacarbonyldicobalt complexes of chiral (non-racemic) unsubstituted terminal alkoxyacetylenes have been synthesized for the first time by a novel procedure that involves one-pot transformation of a chiral alcohol to the corresponding trimethylsilylated alkoxy acetylene, followed by complexation and protodesilylation (also one-pot). The synthesis is efficient and amenable to the preparation of multigram quantities.

  DOI：

  10.1016/0022-328x(94)80183-5
• 作为产物：
  描述：

  (1R*,2S*)-2-(2,4,6-trimethylphenyl)cyclohexanol 在 正丁基锂 、 potassium hydride 作用下， 反应 2.17h， 生成 Trimethyl-[(1R,2S)-2-(2,4,6-trimethyl-phenyl)-cyclohexyloxyethynyl]-silane
  参考文献：
  名称：

  A convenient synthesis of hexacarbonyldicobalt complexes of chiral (non-racemic) terminal alkoxyacetylenes

  摘要：

  The hexacarbonyldicobalt complexes of chiral (non-racemic) unsubstituted terminal alkoxyacetylenes have been synthesized for the first time by a novel procedure that involves one-pot transformation of a chiral alcohol to the corresponding trimethylsilylated alkoxy acetylene, followed by complexation and protodesilylation (also one-pot). The synthesis is efficient and amenable to the preparation of multigram quantities.

  DOI：

  10.1016/0022-328x(94)80183-5