Benzimidazolyl-2-N-(2-chlor-ethyl)-formamid | 14466-75-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并咪唑类
• 英文名称: Benzimidazolyl-2-N-(2-chlor-ethyl)-formamid
• 英文别名: 1H-benzoimidazole-2-carboxylic acid 2-chloro-ethylamide
• CAS: 14466-75-2
• 化学式: C₁₀H₁₀ClN₃O
• 分子量: 223.662
• InChiKey: XTYMGDRDFRXAMI-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  Benzimidazolyl-2-N-(2-chlor-ethyl)-formamid 、 氯甲酸异丙酯 在 吡啶 作用下， 反应 8.0h， 以50%的产率得到2-(2-Chloro-ethylcarbamoyl)-benzoimidazole-1-carboxylic acid isopropyl ester
  参考文献：
  名称：

  Synthesis and antiviral assays of some 2-substituted benzimidazole-N-carbamates

  摘要：

  Some 2-substituted benzimidazole-N-carbamates were synthesized and tested in vitro for antiviral activity. Two derivatives were active at noncytotoxic concentrations. The results confirmed the importance of the substituents at the 2-position of benzimidazole; an isopropylcarboxamide group led to the best activity. (C) 2000 Elsevier Science S.A. All rights reserved.

  DOI：

  10.1016/s0014-827x(99)00117-2