Benzoic acid (1R,2R,3S,4S,5S,6S)-3,4-bis-benzyloxy-2-hydroxy-5,6-bis-(4-methoxy-benzyloxy)-cyclohexylmethyl ester | 220206-39-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Benzoic acid (1R,2R,3S,4S,5S,6S)-3,4-bis-benzyloxy-2-hydroxy-5,6-bis-(4-methoxy-benzyloxy)-cyclohexylmethyl ester
• CAS: 220206-39-3
• 化学式: C₄₄H₄₆O₉
• 分子量: 718.844
• InChiKey: LAYMJTZRHIDGPT-UEECLIOXSA-N

反应信息

• 作为反应物：
  描述：

  Benzoic acid (1R,2R,3S,4S,5S,6S)-3,4-bis-benzyloxy-2-hydroxy-5,6-bis-(4-methoxy-benzyloxy)-cyclohexylmethyl ester 在 sodium hydride 、 二异丁基氢化铝 作用下， 以 N,N-二甲基甲酰胺 、 甲苯 为溶剂， 生成 [(1R,2R,3S,4S,5S,6S)-2,3,4-Tris-benzyloxy-5,6-bis-(4-methoxy-benzyloxy)-cyclohexyl]-methanol
  参考文献：
  名称：

  Synthesis of Bicyclic Derivatives of 5a-Carba-sugars: 6-Hydroxyl Group Conformationally Restricted 5a-Carba-D-mannopyranose Derivatives

  摘要：

  Some bicyclic derivatives of 5a-carba-alpha- and beta-D-mannopyranoses, whose 6-hydroxyl groups are conformationally restricted, have been synthesized in order to provide key components of the trisaccharide mimics designed as inhibitors or substrate analogues useful for elucidation of mechanism and action of GlcNAcT-V.

  DOI：

  10.3987/com-98-s(h)42
• 作为产物：
  描述：

  苯甲酰氯 、 (1R,2S,3S,4S,5S,6R)-2,3-Bis-benzyloxy-6-hydroxymethyl-4,5-bis-(4-methoxy-benzyloxy)-cyclohexanol 、 (2R,4aS,5S,6S,7R,8S,8aR)-7,8-Bis-benzyloxy-5,6-bis-(4-methoxy-benzyloxy)-2-phenyl-hexahydro-benzo[1,3]dioxine 在 溶剂黄146 作用下， 以 水 、 吡啶 为溶剂， 以87%的产率得到Benzoic acid (1R,2R,3S,4S,5S,6S)-3,4-bis-benzyloxy-2-hydroxy-5,6-bis-(4-methoxy-benzyloxy)-cyclohexylmethyl ester
  参考文献：
  名称：

  Synthesis of Bicyclic Derivatives of 5a-Carba-sugars: 6-Hydroxyl Group Conformationally Restricted 5a-Carba-D-mannopyranose Derivatives

  摘要：

  Some bicyclic derivatives of 5a-carba-alpha- and beta-D-mannopyranoses, whose 6-hydroxyl groups are conformationally restricted, have been synthesized in order to provide key components of the trisaccharide mimics designed as inhibitors or substrate analogues useful for elucidation of mechanism and action of GlcNAcT-V.

  DOI：

  10.3987/com-98-s(h)42