| 1341192-97-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• CAS: 1341192-97-9
• 化学式: C₁₃H₁₅NO
• 分子量: 201.268
• InChiKey: JVPNNJXLLQYCIM-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  丙烯酸叔丁酯 、 在 copper diacetate 、 palladium diacetate 、 potassium trifluoroacetate 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 3.0h， 以22%的产率得到1-benzyl-5-(2-(tert-butoxycarbonyl)vinyl)-6-methyl-2,3-dihydropyridin-4(1H)-one
  参考文献：
  名称：

  Palladium(II)-Catalyzed Dehydrogenative Alkenylation of Cyclic Enaminones via the Fujiwara–Moritani Reaction

  摘要：

  A new Pd(II)-catalyzed dehydrogenative alkenylation reaction involving two alkenes was developed. A variety of nonaromatic, cyclic enaminones were successfully coupled to primary and secondary alkenes yielding a series of unique 1,3-dienes. The generality of this transformation presents a useful strategy for directly cross-coupling alkenes and offers an attractive new approach to functionallze enaminones.

  DOI：

  10.1021/ol202677g

文献信息

• Copper-Assisted Palladium(II)-Catalyzed Direct Arylation of Cyclic Enaminones with Arylboronic Acids
  作者：Yong Wook Kim、Micah J. Niphakis、Gunda I. Georg

  DOI：10.1021/jo301531k

  日期：2012.11.2

  Described herein is a palladium(II)-catalyzed direct arylation of cyclic enaminones with arylboronic acids. The versatility of this method is that both electron-rich and electron-poor boronic acids can be coupled in high yields. A mixture of two Cu(II) additives was crucial for efficient cross-coupling. The role of each Cu(II) reagent appears to be distinct and complementary serving to assist catalyst

  本文描述的是钯(II)-催化的环状烯胺酮与芳基硼酸的直接芳基化。这种方法的多功能性在于富电子和缺电子硼酸都可以高产率耦合。两种 Cu(II) 添加剂的混合物对于有效的交叉耦合至关重要。每个 Cu(II) 试剂的作用似乎是不同的和互补的，有助于通过假定的芳基铜中间体帮助催化剂再氧化和金属转移。