(Ss,Ss),-N,N'-(1R,1'R)-1,1'-(anthracene-9,10-diyl)bis(2,2,2-trifluoroethane-1,1-diyl)bis(2-methylpropane-2-sulfinamide) | 1104003-77-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 蒽
• 英文名称: (Ss,Ss),-N,N'-(1R,1'R)-1,1'-(anthracene-9,10-diyl)bis(2,2,2-trifluoroethane-1,1-diyl)bis(2-methylpropane-2-sulfinamide)
• CAS: 1104003-77-1
• 化学式: C₂₆H₃₀F₆N₂O₂S₂
• 分子量: 580.659
• InChiKey: LXBBCBBYXPVQIM-UCPFLVNUSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.3
• 重原子数：
  38.0
• 可旋转键数：
  6.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  58.2
• 氢给体数：
  2.0
• 氢受体数：
  2.0

反应信息

• 作为反应物：
  描述：

  (Ss,Ss),-N,N'-(1R,1'R)-1,1'-(anthracene-9,10-diyl)bis(2,2,2-trifluoroethane-1,1-diyl)bis(2-methylpropane-2-sulfinamide) 在 盐酸 、 甲醇 作用下， 以 1,4-二氧六环 为溶剂， 反应 3.5h， 以70%的产率得到(1R,1'R)-1,1'-(anthracene-9,10-diyl)bis(2,2,2-trifluoroethanamine)
  参考文献：
  名称：

  Preparation of (1R,1′R)-1,1′-(anthracene-9,10-diyl)bis(2,2,2-trifluoroethanamine): a chiral diamine with low basicity

  摘要：

  A new chiral diamine with low basicity was synthesized in enantiopure form. (1R,1'R)-1,1'-(Anthracene-9,10-diyl)bis(2,2,2-trifluoroethanamine) was obtained by means of several stereochemically controlled reactions. The structures of the title compound and several intermediates were studied. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2008.10.082
• 作为产物：
  描述：

  (E,E,Ss,Ss)-N,N'-(anthracene-9,10-diylbis(methan-1-yl-1-ylidene))bis(2-methylpropane-2-sulfinamide) 、 (三氟甲基)三甲基硅烷 在 四甲基氟化铵 作用下， 以 四氢呋喃 为溶剂， 以88%的产率得到(Ss,Ss),-N,N'-(1R,1'R)-1,1'-(anthracene-9,10-diyl)bis(2,2,2-trifluoroethane-1,1-diyl)bis(2-methylpropane-2-sulfinamide)
  参考文献：
  名称：

  Preparation of (1R,1′R)-1,1′-(anthracene-9,10-diyl)bis(2,2,2-trifluoroethanamine): a chiral diamine with low basicity

  摘要：

  A new chiral diamine with low basicity was synthesized in enantiopure form. (1R,1'R)-1,1'-(Anthracene-9,10-diyl)bis(2,2,2-trifluoroethanamine) was obtained by means of several stereochemically controlled reactions. The structures of the title compound and several intermediates were studied. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2008.10.082