7-(2,4,4-Triethoxy-5-oxo-cyclopent-1-enyl)-heptanoic acid ethyl ester | 42607-44-3

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 7-(2,4,4-Triethoxy-5-oxo-cyclopent-1-enyl)-heptanoic acid ethyl ester
• CAS: 42607-44-3
• 化学式: C₂₀H₃₄O₆
• 分子量: 370.486
• InChiKey: YUQUBRKPJNXZSH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.92
• 重原子数：
  26.0
• 可旋转键数：
  14.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  71.06
• 氢给体数：
  0.0
• 氢受体数：
  6.0

反应信息

• 作为反应物：
  描述：

  7-(2,4,4-Triethoxy-5-oxo-cyclopent-1-enyl)-heptanoic acid ethyl ester 在 sodium hydroxide 作用下， 以 乙醇 为溶剂， 生成 1-Cyclopentene-1-heptanoic acid, 2,4,4-triethoxy-5-oxo-
  参考文献：
  名称：

  Cyclopentanones. XVII: Prostaglandin synthesis involving the lithium-liquid ammonia reduction of 3-alkyl-4-hydroxy-2-(1′-octynyl)-2-cyclopentenones

  摘要：

  AbstractThe present paper describes the lithium‐liquid ammonia reduction of 3‐alkyl‐4‐hydroxy‐2‐(1′‐octynyl)‐2‐cyclopentenones; depending on the nature of the 3‐alkyl side chain prostaglandins of the F1‐series or primary prostaglandins of the 2‐series are synthesised.

  DOI：

  10.1002/bscb.19760850706
• 作为产物：
  描述：

  乙醇 、 7-(2-Hydroxy-3,5-dioxo-cyclopent-1-enyl)-heptanoic acid 、 原甲酸三乙酯 生成 7-(2,4,4-Triethoxy-5-oxo-cyclopent-1-enyl)-heptanoic acid ethyl ester
  参考文献：
  名称：

  Cyclopentanones. XVII: Prostaglandin synthesis involving the lithium-liquid ammonia reduction of 3-alkyl-4-hydroxy-2-(1′-octynyl)-2-cyclopentenones

  摘要：

  AbstractThe present paper describes the lithium‐liquid ammonia reduction of 3‐alkyl‐4‐hydroxy‐2‐(1′‐octynyl)‐2‐cyclopentenones; depending on the nature of the 3‐alkyl side chain prostaglandins of the F1‐series or primary prostaglandins of the 2‐series are synthesised.

  DOI：

  10.1002/bscb.19760850706

文献信息

• Cyclopentanones. XVII: Prostaglandin synthesis involving the lithium-liquid ammonia reduction of 3-alkyl-4-hydroxy-2-(1′-octynyl)-2-cyclopentenones
  作者：P. De Clercq、M. De Smet、K. Legein、F. Vanhulle、M. Vandewalle

  DOI：10.1002/bscb.19760850706

  日期：——

  AbstractThe present paper describes the lithium‐liquid ammonia reduction of 3‐alkyl‐4‐hydroxy‐2‐(1′‐octynyl)‐2‐cyclopentenones; depending on the nature of the 3‐alkyl side chain prostaglandins of the F1‐series or primary prostaglandins of the 2‐series are synthesised.