1-ethynyl-4-fluoromethylbenzene | 1035619-61-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-ethynyl-4-fluoromethylbenzene
• 英文别名: 1-Ethynyl-4-(fluoromethyl)benzene
• CAS: 1035619-61-4
• 化学式: C₉H₇F
• 分子量: 134.153
• InChiKey: VYMKWEZWAJCYEA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  10
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  1-ethynyl-4-fluoromethylbenzene 、 苄基叠氮 在 copper(ll) sulfate pentahydrate 、 sodium ascorbate 、 (±)-MonoPhos 作用下， 以 水 、 二甲基亚砜 为溶剂， 反应 2.0h， 以93%的产率得到1-benzyl-4-(4-fluoromethylphenyl)-1H-1,2,3-triazole
  参考文献：
  名称：

  亚磷酰胺可加速铜（i）催化的叠氮化物和炔烃的[3 + 2]环加成反应。

  摘要：

  单齿亚磷酰胺配体可用于加速铜（i）催化的叠氮化物和炔烃（CuAAC）的1,3-偶极环加成反应，从而迅速生成各种官能化的1,4-二取代-1,2,3-三唑。Cu（i）和Cu（ii）盐均充当水溶液中的铜源，以提供优异的收率。

  DOI：

  10.1039/b822994e

文献信息

• [EN] CBD CANNABINOIDS AND CBD CANNABINOID ANALOGUES<br/>[FR] CANNABINOÏDES CBD ET ANALOGUES DE CANNABINOÏDES CBD
  申请人：BOTANIX PHARMACEUTICALS LTD

  公开号：WO2022133544A1

  公开（公告）日：2022-06-30

  Cannabidiol (CBD) cannabinoids and CBD cannabinoid analogues with, inter alia, antimicrobial activity, synthetic methods for the preparation thereof and medical uses and formulations containing same.

  大麻二酚（CBD）大麻素及CBD类似物具有抗微生物活性，其制备的合成方法以及含有其的医疗用途和制剂。
• CROSSLINKABLE AROMATIC RESINS HAVING PROTONIC ACID GROUPS AND ION CONDUCTIVE POLYMER MEMBRANES BINDERS AND FUEL CELLS MADE BY USING THE SAME
  申请人：Mitsui Chemicals, Inc.

  公开号：EP1457511A1

  公开（公告）日：2004-09-15

  The invention provides a crosslinkable aromatic resin having a protonic acid group and a crosslinkable group, suitable for electrolytic membranes and binders used in fuel cells, etc., and electrolytic polymer membranes, binders and fuel cells using the resin. The crosslinkable aromatic resin has a crosslinkable group, which is not derived from the protonic acid group and can form a polymer network without any elimination component. This resin exhibits excellent ion conductivity, heat resistance, water resistance, adhesion property and low methanol permeability. Preferably, the crosslinkable group is composed of a C1 to C10 alkyl group directly bonded to the aromatic ring and a carbonyl group, or a carbon-carbon double bond or triple bond. The aromatic resins such as aromatic polyethers, aromatic polyamides, aromatic polyimides, aromatic polyamideimides, aromatic polyazoles, etc., which contain such a crosslinkable group, are preferred as the crosslinkable aromatic resins having a protonic acid group and a crosslinkable group.

  本发明提供了一种具有质子酸基团和可交联基团的可交联芳香族树脂，适用于燃料电池等中使用的电解膜和粘结剂，以及使用该树脂的电解聚合物膜、粘结剂和燃料电池。可交联芳香族树脂具有可交联基团，该基团并非来自质子酸基团，可形成聚合物网络，且不含任何消除成分。这种树脂具有优异的离子传导性、耐热性、耐水性、粘附性和低甲醇渗透性。可交联基团最好由直接键合在芳香环上的 C1 至 C10 烷基和羰基或碳碳双键或三键组成。芳香族树脂，如芳香族聚醚、芳香族聚酰胺、芳香族聚酰亚胺、芳香族聚酰胺酰亚胺、芳香族聚唑等，含有这样的可交联基团，作为具有质子酸基团和可交联基团的可交联芳香族树脂，是优选的。
• AROMATIC HYDROCARBON-BASE PROTON EXCHANGE MEMBRANE AND DIRECT METHANOL FUEL CELL USING SAME
  申请人：Toyo Boseki Kabushiki Kaisha

  公开号：EP1826846A1

  公开（公告）日：2007-08-29

  A proton exchange membrane is obtained which can give an excellent power generation characteristic when the membrane is applied to, in particular, a fuel cell wherein high-concentration methanol is used as a fuel. In the aromatic hydrocarbon based proton exchange membrane of the invention, the ion exchange capacity is set into the range of 0.6 to 1.3 meq/g. Moreover, the area swelling rate for a 30% by mass methanol aqueous solution at 40°C is set into the range of 2 to 30%. Preferably, a sulfonic acid group is bonded to an aromatic ring of the aromatic hydrocarbon based polymer contained in the aromatic hydrocarbon based proton exchange film. Preferably, the aromatic hydrocarbon based polymer is a polyarylene ether based polymer.

  本发明获得了一种质子交换膜，当将该膜应用于燃料电池，特别是使用高浓度甲醇作为燃料的燃料电池时，该膜可提供出色的发电特性。在本发明的芳香烃基质子交换膜中，离子交换容量设定在 0.6 至 1.3 meq/g 的范围内。此外，在 40°C 时，质量分数为 30% 的甲醇水溶液的面积膨胀率设定为 2% 至 30%。优选地，磺酸基与芳香烃基质子交换膜中所含芳香烃基聚合物的芳香环键合。芳香烃基聚合物最好是聚芳醚基聚合物。
• SULFONIC ACID GROUP-CONTAINING POLYMER, METHOD FOR PRODUCING SAME, RESIN COMPOSITION CONTAINING SUCH SULFONIC ACID GROUP-CONTAINING POLYMER, POLYMER ELECTROLYTE MEMBRANE, POLYMER ELECTROLYTE MEMBRANE/ELECTRODE ASSEMBLY, AND FUEL CELL
  申请人：Toyo Boseki Kabushiki Kaisha

  公开号：EP1889863A1

  公开（公告）日：2008-02-20

  The present invention relates to a sulfonic acid group-containing polymer excellent in ion conductivity and durability, a method for producing the same, a resin composition containing the sulfonic acid group-containing polymer, a polymer electrolyte membrane, a polymer electrolyte membrane/electrode assembly, and a fuel cell. The sulfonic acid group-containing polymer of the present invention, in a first embodiment, includes a constituent represented by the following chemical formula 1: wherein X represents hydrogen or a monovalent cation species; Y represents a sulfone group or a ketone group; and n represents an arbitrary integer not less than 2.

  本发明涉及一种离子传导性和耐久性极佳的含磺酸基聚合物、其生产方法、含有该含磺酸基聚合物的树脂组合物、聚合物电解质膜、聚合物电解质膜/电极组件和燃料电池。在第一个实施方案中，本发明的含磺酸基聚合物包括由以下化学式表示的成分 1： 其中 X 代表氢或一价阳离子种类；Y 代表砜基或酮基；n 代表不小于 2 的任意整数。
• Crosslinkable aromatic resin having protonic acid group, and ion conductive polymer membrane, binder and fuel cell using the resin
  申请人：MITSUI CHEMICALS, INC.

  公开号：US20040191602A1

  公开（公告）日：2004-09-30

  The invention provides a crosslinkable aromatic resin having a protonic acid group and a crosslinkable group, suitable for electrolytic membranes and binders used in fuel cells, etc., and electrolytic polymer membranes, binders and fuel cells using the resin. The crosslinkable aromatic resin has a crosslinkable group, which is not derived from the protonic acid group and can form a polymer network without any elimination component. This resin exhibits excellent ion conductivity, heat resistance, water resistance, adhesion property and low methanol permeability. Preferably, the crosslinkable group is composed of a C 1 to C 10 alkyl group directly bonded to the aromatic ring and/or an alkylene group having 1 to 3 carbon atoms in the main chain in which at least one carbon atom directly bonded to the aromatic ring bonds to hydrogen, and a carbonyl group, or a carbon-carbon double bond or triple bond. The aromatic resins such as aromatic polyethers, aromatic polyamides, aromatic polyimides, aromatic polyamideimides, aromatic polyazoles, etc., which contain such a crosslinkable group, are preferred as the crosslinkable aromatic resins having a protonic acid group and a crosslinkable group.

  本发明提供了一种具有质子酸基团和可交联基团的可交联芳香族树脂，适用于燃料电池等中使用的电解膜和粘结剂，以及使用该树脂的电解聚合物膜、粘结剂和燃料电池。可交联芳香族树脂具有可交联基团，该基团并非来自质子酸基团，可形成聚合物网络，且不含任何消除成分。这种树脂具有优异的离子传导性、耐热性、耐水性、粘附性和低甲醇渗透性。可交联基团最好由 C 1 至 C 10 烷基和/或主链上有 1 至 3 个碳原子的亚烷基，其中至少有一个直接与芳香环键合的碳原子与氢、羰基或碳碳双键或三键键合。芳香族树脂，如芳香族聚醚、芳香族聚酰胺、芳香族聚酰亚胺、芳香族聚酰胺酰亚胺、芳香族聚唑等，含有这样的可交联基团，作为具有质子酸基团和可交联基团的可交联芳香族树脂是首选。