methyl N-ethoxy-N-2-methylphenylcarbamate | 151827-85-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: methyl N-ethoxy-N-2-methylphenylcarbamate
• 英文别名: methyl N-ethoxy-N-(2-methylphenyl)carbamate
• CAS: 151827-85-9
• 化学式: C₁₁H₁₅NO₃
• 分子量: 209.245
• InChiKey: COYWERCEUKEURL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  15
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  38.8
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  methyl N-ethoxy-N-2-methylphenylcarbamate 在 N-溴代丁二酰亚胺(NBS) 作用下， 以 四氯化碳 、 水 为溶剂， 以68%的产率得到methyl N-2-bromomethylphenyl-N-ethoxycarbamate
  参考文献：
  名称：

  N-substituted phenylcarbamic acid derivatives, a process for production

  摘要：

  一种由通式(I)表示的N-取代苯基甲酸衍生物：##STR1## [其中R.sup.1为H，(C.sub.1-6)烷基，卤代(C.sub.1-6)烷基，(C.sub.1-6)烷氧基(C.sub.1-6)烷基，(C.sub.2-6)烯基，(C.sub.2-6)炔基或卤代(C.sub.1-6)烷氧基(C.sub.1-6)烷基，R.sup.2为H，(C.sub.1-6)烷基，卤代(C.sub.1-6)烷基，(C.sub.1-6)烷氧基(C.sub.1-6)烷基，(C.sub.2-6)烯基，(C.sub.2-6)炔基，卤代(C.sub.1-6)烷氧基(C.sub.1-6)烷基或氰基(C.sub.1-6)烷基，R.sup.3为(C.sub.1-6)烷基或卤代(C.sub.1-6)烷基，R.sup.4和R.sup.5分别为特定基团，Y为O或S]，对控制白粉病、疮痂病、晚疫病和灰霉病非常有效；一种生产该衍生物的方法；一种包含该衍生物作为活性成分的农业和园艺杀菌剂；该衍生物的中间体；以及生产该中间体的方法。

  公开号：

  US05650434A1

文献信息

• N-Substituted phennylcarbamic acid derivates a process for production thereof, and agricultural and horticultural fungicides
  申请人：NIHON NOHYAKU CO., LTD.

  公开号：EP0619301A2

  公开（公告）日：1994-10-12

  An N-substituted phenylcarbamic acid derivative represented by the general formula: [wherein as disclosed in the specification, each of R1 and R2 is an alkyl group or the like, X is O, S or N(R8), and R3 is -N = C(R4)R5 or the like in the case of X being O], a process for producing said derivative, and an agricultural and horticultural fungicide containing said derivative as an active ingredient.

  由通式代表的 N-取代苯基氨基甲酸衍生物： [其中 R1 和 R2 均为烷基或类似基团，X 为 O、S 或 N(R8)，在 X 为 O 的情况下，R3 为 -N = C(R4)R5 或类似基团]，一种生产所述衍生物的工艺，以及一种含有所述衍生物作为活性成分的农用和园艺杀菌剂。
• N-substituted phenylcarbamic acid derivatives, a process for production thereof, agricultural and horticultural fungicides, intermediates of the derivatives and a process for production thereof
  申请人：NIHON NOHYAKU CO., LTD.

  公开号：EP0704430B1

  公开（公告）日：1998-07-29
• US5650434A
  申请人：——

  公开号：US5650434A

  公开（公告）日：1997-07-22
• US5712399A
  申请人：——

  公开号：US5712399A

  公开（公告）日：1998-01-27
• N-substituted phenylcarbamic acid derivatives, a process for production
  申请人：Nihon Nohyaku Co., Ltd.

  公开号：US05650434A1

  公开（公告）日：1997-07-22

  An N-substituted phenylcarbamic acid derivative represented by the general formula (I): ##STR1## [wherein R.sup.1 is H, a (C.sub.1-6)alkyl group, a halo(C.sub.1-6)alkyl group, a (C.sub.1-6)alkoxy(C.sub.1-6)alkyl group, a (C.sub.2-6)alkenyl group, a (C.sub.2-6)alkynyl group or a halo(C.sub.1-6)alkoxy(C.sub.1-6)alkyl group, R.sup.2 is H, a (C.sub.1-6)alkyl group, a halo(C.sub.1-6)alkyl group, a (C.sub.1-6)alkoxy(C.sub.1-6)alkyl group, a (C.sub.2-6)alkenyl group, a (C.sub.2-6)alkynyl group, a halo(C.sub.1-6)alkoxy(C.sub.1-6)alkyl group or a cyano(C.sub.1-6)alkyl group, R.sup.3 is a (C.sub.1-6)alkyl group or a halo(C.sub.1-6)alkyl group, each of R.sup.4 and R.sup.5 is a specific group, and Y is O or S] which is very effective in controlling powdery mildew, scab, late blight and gray mold; a process for producing said derivative; an agricultural and horticultural fungicide containing said derivative as an active ingredient; an intermediate of said derivative; and a process for producing the intermediate.

  一种由通式(I)表示的N-取代苯基甲酸衍生物：##STR1## [其中R.sup.1为H，(C.sub.1-6)烷基，卤代(C.sub.1-6)烷基，(C.sub.1-6)烷氧基(C.sub.1-6)烷基，(C.sub.2-6)烯基，(C.sub.2-6)炔基或卤代(C.sub.1-6)烷氧基(C.sub.1-6)烷基，R.sup.2为H，(C.sub.1-6)烷基，卤代(C.sub.1-6)烷基，(C.sub.1-6)烷氧基(C.sub.1-6)烷基，(C.sub.2-6)烯基，(C.sub.2-6)炔基，卤代(C.sub.1-6)烷氧基(C.sub.1-6)烷基或氰基(C.sub.1-6)烷基，R.sup.3为(C.sub.1-6)烷基或卤代(C.sub.1-6)烷基，R.sup.4和R.sup.5分别为特定基团，Y为O或S]，对控制白粉病、疮痂病、晚疫病和灰霉病非常有效；一种生产该衍生物的方法；一种包含该衍生物作为活性成分的农业和园艺杀菌剂；该衍生物的中间体；以及生产该中间体的方法。