1,2-Dipentadecanoyl-rac-glycerol | 98896-79-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 甘油脂
• 英文名称: 1,2-Dipentadecanoyl-rac-glycerol
• 英文别名: Dipentadecanoin；(3-hydroxy-2-pentadecanoyloxypropyl) pentadecanoate
• CAS: 98896-79-8
• 化学式: C₃₃H₆₄O₅
• 分子量: 540.868
• InChiKey: FWYXULJVROPNGE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  13
• 重原子数：
  38
• 可旋转键数：
  32
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.94
• 拓扑面积：
  72.8
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  2-溴乙基二氯膦酸酯 、 1,2-Dipentadecanoyl-rac-glycerol 、 三甲胺 生成 dimyristoylphosphatidylcholine
  参考文献：
  名称：

  胆碱磷脂的合成，I。用于合成α-和β-卵磷脂及其醚类似物

  摘要：

  卵磷脂及其醚类似物的合成方法，其中二酰基或。在三乙胺存在下，使二-O-烷基甘油二酸酯（1）与β-溴乙基-磷酸二氯化物反应，然后用三甲胺将其转化为磷酰胆碱4，以使任何短链（最高为C 8）改性，卵磷脂及其醚类似物可通过薄层色谱法以分析纯的形式均匀地获得（参见表1）。

  DOI：

  10.1002/jlac.19677090124

文献信息

• Process for producing polyol fatty acid monoesters
  申请人：LION CORPORATION

  公开号：EP0407959A2

  公开（公告）日：1991-01-16

  A polyol fatty acid monoester can be produced with an industrial advantage at high synthesis ratio upon (1) mixing and reacting a saturated or unsaturated fatty acid having 6 to 22 carbon atoms or an ester of such a fatty acid with a lower alcohol having 1 to 3 carbon atoms and a polyol selected from glycerol and its derivatives, polyglycerol and its derivatives, ethylene glycol, polyethylene glycol, propylene glycol and polypropylene glycol or (2) mixing and reacting a glyceride oil or fat comprising a saturated or unsaturated fatty acid having 6 to 22 carbon atoms as the constituent fatty acid and one or more of the above polyols, wherein an enzymatic reaction is conducted by using an immobilized thermostable lipase under the presence of a secondary or tertiary alcohol.

  (1) 将具有 6 至 22 个碳原子的饱和或不饱和脂肪酸或这种脂肪酸的酯与具有 1 至 3 个碳原子的低级醇和选自甘油及其衍生物、聚甘油及其衍生物、乙二醇、聚乙二醇、丙二醇和聚丙二醇的多元醇混合并反应，或 (2) 将由具有 6 至 22 个碳原子的饱和或不饱和脂肪酸组成的甘油酯油或脂肪与选自甘油及其衍生物、聚甘油及其衍生物、乙二醇、聚乙二醇、丙二醇和聚丙二醇的多元醇混合并反应，可以高合成比生产具有工业优势的多元醇脂肪酸单酯、聚乙二醇、丙二醇和聚丙二醇，或 (2) 混合甘油酯油或脂肪并使其反应，甘油酯油或脂肪的组成脂肪酸为具有 6 至 22 个碳原子的饱和或不饱和脂肪酸，以及一种或多种上述多元醇，其中酶反应是在仲醇或叔醇存在下通过使用固定化恒温脂肪酶进行的。
• Cosmestic composition
  申请人：UNILEVER PLC

  公开号：EP0572167A1

  公开（公告）日：1993-12-01

  A composition suitable for topical application to mammalian skin and hair for inducing, maintaining or increasing hair growth comprises a hair growth promoter chosen from glutamic acid derivatives and salts thereof. The composition preferably also comprises an activity enhancer which may be chosen from hair growth stimulants, penetration enhancers and cationic polymers.

  一种适用于哺乳动物皮肤和毛发的外用组合物，可诱导、维持或增加毛发生长，其中包括一种毛发生长促进剂，选自谷氨酸衍生物及其盐类。该组合物最好还包含一种活性增强剂，它可以选自毛发生长刺激剂、渗透增强剂和阳离子聚合物。
• Cosmetic composition containing DOPA derivatives
  申请人：UNILEVER PLC

  公开号：EP0580409A2

  公开（公告）日：1994-01-26

  A composition for topical application to human hair or skin contains a chemical analogue of dihydroxyphenyl alanine (DOPA). This chemical analogue can be absorbed by skin or by a hair follicle and metabolised in-vivo, thus leading to the formation of melanin in skin or to the growth of melanin-pigmented hair. Consequently the composition can give controlled skin darkening to mimic sun-induced tanning or can bring about the growth of dar hair in place of the grey or white hair.

  一种用于人体毛发或皮肤局部涂抹的组合物含有一种二羟基苯丙氨酸（DOPA）的化学类似物。这种化学类似物可被皮肤或毛囊吸收并在体内代谢，从而导致皮肤黑色素的形成或黑色素毛发的生长。因此，这种成分可以控制皮肤变黑，模拟日光引起的晒黑，或使灰发或白发长出黑发。
• Cosmetic composition containing hair-growth promoter
  申请人：UNILEVER PLC

  公开号：EP0571198A1

  公开（公告）日：1993-11-24

  A composition suitable for topical application to mammalian skin and hair for inducing, maintaining or increasing hair growth comprises a hair growth promoter chosen from glutamine derivatives and salts thereof. The composition preferably also comprises an activity enhancer which may be chosen from hair growth stimulants, penetration enhancers and cationic polymers.

  一种适用于哺乳动物皮肤和毛发的外用组合物，可诱导、维持或增加毛发生长，其中包括一种毛发生长促进剂，选自谷氨酰胺衍生物及其盐类。该组合物最好还包含一种活性增强剂，它可以选自毛发生长刺激剂、渗透增强剂和阳离子聚合物。
• HAIR TONIC COMPOSITION
  申请人：Lion Corporation

  公开号：EP1671616A1

  公开（公告）日：2006-06-21

  Provided is a hair growth promoter which has an excellent hair growth effect and provides an excellent stabilization effect at low temperature and which provides good use feeling having no stickiness. The hair growth promoter is an ethanol or aqueous ethanol preparation comprising, as active ingredients for a hair growth promoter, (A) at least one compound selected from fatty acids having a chain length of an odd number of carbon atoms, the derivatives of the fatty acids, aliphatic alcohols having a chain length of an odd number of carbon atoms and the derivatives of the aliphatic alcohols and (B) at least one selected from 6-benzylaminopurine and/or the derivatives thereof represented by the following Formula (I), wherein it further comprises (C) at least one of polyglycerin fatty acid esters and (D) at least one of sorbitan fatty acid esters: in Formula (I), R1 is an alkyl group having 1 to 22 carbon atoms, a cyclic hydrocarbon group, an alkenyl group having 1 to 22 carbon atoms, an aralkyl group which is non-substituted or has a substituent, a styryl group which is non-substituted or has a substituent, an alkylamino group, an amino group having a cyclic hydrocarbon group, an alkenylamino group, a benzylamino group which is non-substituted or has a substituent, a phenylethylamino group which is non-substituted or has a substituent, a phenylamino group which is non-substituted or has a substituent, a phenylaminocarbonylamino group which is non-substituted or has a substituent, a pyridylamino group, a pyridylmethylamino group, a pyrrolylmethylamino group, an oxazolylmethylamino group, an imidazolylmethylamino group, a pyridazolylmethylamino group, a naphthylamino group or a naphthylmethylamino group, and R2 is a hydrogen atom, a pentose or hexose.

  本发明提供了一种生发促进剂，它具有极佳的生发效果，在低温下具有极佳的稳定效果，并且使用感良好，没有粘性。 该生发促进剂是一种乙醇或乙醇水溶液制剂，作为生发促进剂的活性成分，它包括 (A) 至少一种选自碳原子链长为奇数的脂肪酸、脂肪酸衍生物的化合物、(B) 至少一种选自 6-苄基氨基嘌呤和/或由下式（I）表示的其衍生物的化合物， 其中还包括 (C) 至少一种聚甘油脂肪酸酯和 (D) 至少一种山梨糖醇脂肪酸酯： 在式(I)中，R1 是具有 1 至 22 个碳原子的烷基、环状烃基、具有 1 至 22 个碳原子的烯基、未被取代或具有取代基的芳基、未被取代或具有取代基的苯乙烯基、烷基氨基、具有环状烃基的氨基、烯基氨基、未被取代或具有取代基的苄基氨基、未被取代或带有取代基的苯乙基氨基、未被取代或带有取代基的苯氨基、未被取代或带有取代基的苯氨羰基氨基、吡啶基氨基、吡啶基甲基氨基、吡咯基甲基氨基、噁唑基甲基氨基、咪唑基甲基氨基、哒唑基 甲基氨基、萘基氨基或萘基甲基氨基，以及 R2 是氢原子、戊糖或己糖。