lysyllysine

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: lysyllysine
• 英文别名: 2-Amino-6-(2,6-diaminohexanoylamino)hexanoic acid
• 化学式: C₁₂H₂₆N₄O₃
• 分子量: 274.363
• InChiKey: ISWYJQKGNGBKJG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.7
• 重原子数：
  19
• 可旋转键数：
  11
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  145
• 氢给体数：
  5
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  Reinecke salt 、 lysyllysine 以 水 为溶剂， 生成 lysyllysiniumtetrathiocyanatodiamminechromate(III)
  参考文献：
  名称：

  Waley, S. G.; Watson, J., Journal of the Chemical Society

  摘要：

  DOI：

文献信息

• POLYMERIZABLE COMPOSITION FOR OPHTHALMIC AND MEDICAL USE AND ANTIBACTERIAL COMPOSITION OBTAINED BY POLYMERIZING SAME
  申请人：Nanyang Technological University

  公开号：EP2578244A1

  公开（公告）日：2013-04-10

  An object of the present invention is to provide a polymerizable composition capable of providing antimicrobial properties to ophthalmic and medical devices relatively inexpensively with ease, and an antimicrobial composition obtained by polymerizing the polymerizable composition. A polymerizable composition for ophthalmic or medical use comprising an epsilon-polylysine having (meth)acryloyl group is provided. The content of the epsilon-polylysine having (meth)acryloyl group in the polymerizable composition is preferably about 0.1 to 99% by weight, based on the whole amount of the composition. A coating agent for ophthalmic or medical use comprising the above polymerizable composition, an antimicrobial composition for ophthalmic or medical use obtained by polymerizing the above polymerizable composition, an ophthalmic or medical device comprising the antimicrobial composition, and a contact lens comprising the antimicrobial composition are also provided.

  本发明的目的是提供一种可聚合组合物，该组合物能够以相对低廉的价格轻松地为眼科和医疗设备提供抗菌特性，并提供一种通过聚合该可聚合组合物而获得的抗菌组合物。 本发明提供了一种用于眼科或医疗用途的可聚合组合物，该组合物包含一种具有（甲基）丙烯酰基的ε-聚赖氨酸。在可聚合组合物中，具有（甲基）丙烯酰基的ε-聚赖氨酸的含量按组合物总量计算，优选约为 0.1 至 99%（重量百分比）。还提供了包含上述可聚合组合物的眼科或医疗用涂层剂、通过聚合上述可聚合组合物获得的眼科或医疗用抗菌组合物、包含该抗菌组合物的眼科或医疗设备以及包含该抗菌组合物的隐形眼镜。
• Gmelin Handbuch der Anorganischen Chemie, Gmelin Handbook: Cr: MVol.C, 116, page 262 - 264
  作者：

  DOI：——

  日期：——
• SULFATED MOLECULAR UMBRELLAS CONTAINING 6-200 CHOLANIC ACID (DERIVATIVE) UNITS AS ANTI-HIV AND ANTI-HSV AGENTS
  申请人：Lehigh University

  公开号：EP1817325B1

  公开（公告）日：2009-01-21
• PHOTO-COUPLED SYNERGISTICALLY CROSSLINKED HYDROGEL MATERIAL AND ITS COMPOSITION, PREPARATION METHOD, USE, PRODUCT, AND PREPARATION KIT
  申请人：Zhongshan Guanghe Medical Technology Co., Ltd.

  公开号：US20200262939A1

  公开（公告）日：2020-08-20

  This invention provides a preparation, composition, product, and application of a photo-coupled synergistically crosslinked hydrogel material. The preparation includes dissolving Component A including a photosensitive polymer derivative having o-nitrobenzyl phototriggers and Component B including a polymer derivative having amine or alkene (double group) or sulfhydryl group in a biocompatible medium to obtain solution A and solution B, respectively; mixing the solution A and solution B homogeneously to obtain a hydrogel precursor solution; initiating photo-coupled synergistic crosslinking under an irradiation of a UV light to form the hydrogel. The irradiation causes the o-nitrobenzyl phototriggers to generate an aldehyde group/keto group or a nitroso group to initiate photo-coupled synergetic crosslinking. The photo-coupled synergistically crosslinked hydrogel has applications in tissue engineering, regenerative medicine, 3D printing and as a carrier of cell, protein or drug.
• US9238715B2
  申请人：——

  公开号：US9238715B2

  公开（公告）日：2016-01-19