2-(4-trifluoromethoxyphenyl)-5-chloro-4-isothiazolin-3-on | 164348-32-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 2-(4-trifluoromethoxyphenyl)-5-chloro-4-isothiazolin-3-on
• 英文别名: 5-chloro-2-[4-(trifluoromethoxy)phenyl]-1,2-thiazol-3-one
• CAS: 164348-32-7
• 化学式: C₁₀H₅ClF₃NO₂S
• 分子量: 295.669
• InChiKey: ZFTCSFLTIIMHIG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  18
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  54.8
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  2-(4-trifluoromethoxyphenyl)-5-chloro-4-isothiazolin-3-on 在 磺酰氯 、 碳酸氢钠 作用下， 以 二氯甲烷 为溶剂， 生成 2-(4-trifluoromethoxyphenyl)-4,5-dichloro-4-isothiazolin-3-on
  参考文献：
  名称：

  US5552423

  摘要：

  公开号：

文献信息

• Isothiazolone derivative and microbicidal composition comprising the
  申请人：Sumitomo Chemical Company, Limited

  公开号：US05663436A1

  公开（公告）日：1997-09-02

  There is disclosed a novel isothiazolone derivative of the formula: ##STR1## wherein X.sup.1 and X.sup.2 are the same or different and are independently hydrogen, chlorine or bromine; and R is haloalkoxy. The isothiazolone derivative is effective as a microbicide. Also disclosed are a microbicidal composition containing the isothiazolone derivative as an active ingredient, and an intermediate compound for use in the production of the isothiazolone derivative.

  本发明公开了一种新型异噻唑啉衍生物，其化学式为：##STR1##其中X1和X2相同或不同，且独立地为氢、氯或溴；R为卤代烷氧基。该异噻唑啉衍生物对微生物具有有效的杀菌作用。本发明还公开了一种含有该异噻唑啉衍生物作为活性成分的杀菌组合物和用于生产该异噻唑啉衍生物的中间化合物。
• Anti-fouling compositions comprising N-phenylisothiazalone derivatives
  申请人：Chugoku Marine Paints, Ltd.

  公开号：US05683686A1

  公开（公告）日：1997-11-04

  There are disclosed a controlling agent and an antifouling composition against harmful aquatic organisms, which include a particular N-phenylisothiazolone derivative of the formula: ##STR1## wherein X.sup.1 and X.sup.2 are the same or different and are independently hydrogen, chlorine or bromine; and R is haloalkoxy. Also disclosed is a method for preventing or inhibiting the adhesion of harmful aquatic organisms to water-exposed articles, which includes applying the antifouling composition to the water-exposed articles.

  公开了一种控制剂和一种抗有害水生生物的防污组合物，包括特定的N-苯基异噻唑酮衍生物，其化学式为：##STR1## 其中X.sup.1和X.sup.2相同或不同，且独立地是氢、氯或溴；R是卤代烷氧基。还公开了一种防止或抑制有害水生生物附着在水暴露的物品上的方法，其中包括将防污组合物应用于水暴露的物品上。
• Isothiazolone derivative and microbicidal composition comprising the same as active ingredient
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：EP0648757A1

  公开（公告）日：1995-04-19

  There is disclosed a novel isothiazolone derivative of the formula: wherein X¹ and X² are the same or different and are independently hydrogen, chlorine or bromine; and R is haloalkoxy. The isothiazolone derivative is effective as a microbicide. Also disclosed are a microbicidal composition containing the isothiazolone derivative as an active ingredient, and an intermediate compound for use in the production of the isothiazolone derivative.

  本发明公开了一种新型异噻唑啉酮衍生物，其化学式为 其中 X¹ 和 X² 相同或不同，且独立地为氢、氯或溴；R 为卤代烷氧基。异噻唑啉酮衍生物作为杀微生物剂是有效的。还公开了一种含有异噻唑啉酮衍生物作为活性成分的杀微生物组合物，以及一种用于生产异噻唑啉酮衍生物的中间化合物。
• Anti-fouling compositions and fouling control of harmful aquatic organisms
  申请人：Chugoku Marine Paints, Ltd.

  公开号：EP0659847A1

  公开（公告）日：1995-06-28

  There are disclosed a controlling agent and an antifouling composition against harmful aquatic organisms, which include a particular N-phenylisothiazolone derivative of the formula: wherein X¹ and X² are the same or different and are independently hydrogen, chlorine or bromine; and R is haloalkoxy. Also disclosed is a method for preventing or inhibiting the adhesion of harmful aquatic organisms to water-exposed articles, which includes applying the antifouling composition to the water-exposed articles.

  公开了一种防治有害水生生物的控制剂和防污组合物，其中包括一种特定的式 N-苯基异噻唑啉酮衍生物： 其中 X¹ 和 X² 相同或不同，且独立地为氢、氯或溴；R 为卤代烷氧基。还公开了一种防止或抑制有害水生生物粘附到暴露在水中的物品上的方法，其中包括将防污组合物涂到暴露在水中的物品上。
• Phenylamides as marine antifouling agents
  申请人：ROHM AND HAAS COMPANY

  公开号：EP0835605A1

  公开（公告）日：1998-04-15

  Disclosed is a method of inhibiting the growth of marine organisms on a marine structure, by applying onto or into the marine structure a phenylamide compound. These compounds may be directly incorporated into the marine structure during manufacture, directly applied to the structure, or applied to the structure by means of a coating.

  本发明公开了一种抑制海洋生物在海洋结构物上生长的方法，方法是在海洋结构物上或海洋结构物内施用苯基酰胺化合物。这些化合物可以在制造过程中直接加入海洋结构物中，也可以直接涂抹在海洋结构物上，或通过涂层涂抹在海洋结构物上。