2,3-difluoro-1-(4-propylbicyclohexyl)-phenol | 207448-09-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2,3-difluoro-1-(4-propylbicyclohexyl)-phenol
• 英文别名: 2,3-difluoro-4-(4-(4-propylcyclohexyl)cyclohexyl)phenol；2,3-Difluoro-4-(4'-propyl[1,1'-bicyclohexyl]-4-yl)phenol；2,3-difluoro-4-[4-(4-propylcyclohexyl)cyclohexyl]phenol
• CAS: 207448-09-7
• 化学式: C₂₁H₃₀F₂O
• 分子量: 336.465
• InChiKey: NQAQHDDDUCYXMB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.1
• 重原子数：
  24
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2,3-difluoro-1-(4-propylbicyclohexyl)-phenol 、 2,2,2-三氟乙基甲磺酸酯 在 potassium carbonate 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 以82 %的产率得到4-(2,3-difluoro-4-(2,2,2-trifluoroethoxy)phenyl)-4'-propylbi(cyclohexane)
  参考文献：
  名称：

  CN111454729

  摘要：

  公开号：
• 作为产物：
  描述：

  1-(4-propyl-cyclohexyl)-4-(2,3-difluoro-4-methoxyphenyl)cyclohexane 在 三溴化硼 作用下， 以 乙醚 、 二氯甲烷 、 水 为溶剂， 生成 2,3-difluoro-1-(4-propylbicyclohexyl)-phenol
  参考文献：
  名称：

  EP1026142

  摘要：

  公开号：

文献信息

• LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE
  申请人：Shimada Teru

  公开号：US20100328600A1

  公开（公告）日：2010-12-30

  The invention provides a liquid crystal compound having stability to heat, light and so forth, a wide temperature range of a nematic phase, a small viscosity, a suitable optical anisotropy, a suitable elastic constant K 33 , a suitable and negative dielectric anisotropy, and an excellent compatibility with other liquid crystal compounds. The invention provides a liquid crystal composition containing the compound described above and having stability to heat, light and so forth, a small viscosity, a suitable optical anisotropy, a suitable and negative dielectric anisotropy, a suitable elastic constant K 33 , a low threshold voltage, a high maximum temperature of a nematic phase, and a low minimum temperature of the nematic phase. The invention also provides a liquid crystal display device having a short response time, a small power consumption, a low driving voltage, and a large contrast, and containing the composition described above which can be used in a large temperature range. For example, a liquid crystal compound having four or more rings in which the central ring has 2,3-difluorophenoxy such as trans-4′-[2,3-difluoro-4-(trans-4-propylcyclohexyl)phenoxymethyl]-trans-4-pentylbicyclohexyl is provided. Further provided is a liquid crystal composition containing the compound, and a liquid crystal display device using this liquid crystal composition.

  本发明提供了一种液晶化合物，具有耐热、耐光等稳定性，具有广泛的向列相温度范围，粘度小，适当的光学各向异性，适当的弹性常数K33，适当的负介电各向异性，并且与其他液晶化合物具有良好的相容性。本发明还提供了一种液晶组合物，包含上述化合物，并具有耐热、耐光等稳定性，粘度小，适当的光学各向异性，适当的负介电各向异性，适当的弹性常数K33，低阈值电压，向列相的最高温度高，向列相的最低温度低。本发明还提供了一种液晶显示装置，具有短的响应时间，小的功耗，低的驱动电压和大的对比度，并包含上述组合物，可在广泛的温度范围内使用。例如，提供了一种具有四个或更多环的液晶化合物，其中中心环具有2,3-二氟苯氧基，例如trans-4'-[2,3-二氟-4-(trans-4-丙基环己基)苯氧甲基]-trans-4-戊基双环己烷。还提供了一种含有该化合物的液晶组合物和使用该液晶组合物的液晶显示装置。
• 2,3-DIFLUOROPHENYL DERIVATIVES HAVING NEGATIVE VALUE OF PERMITTIVITY ANISOTROPY, LIQUID-CRYSTAL COMPOSITION, AND LIQUID-CRYSTAL DISPLAY ELEMENT
  申请人：CHISSO CORPORATION

  公开号：EP1026142A1

  公开（公告）日：2000-08-09

  The invention is to provide liquid crystalline compounds having a negative and large dielectric anisotropy value and a small optical anisotropy value; liquid crystal compositions comprising the compound; and liquid crystal display devices fabricated by using the liquid crystal composition; the liquid crystalline compounds have 2,3-difluorophenyl moiety and are expressed by the general formula (1) wherein Ra and Rb represent an alkyl group or alkoxy group having 1 to 10 carbon atoms, but any one or more methylene groups in at least one of the Ra and Rb are replaced by cyclopropane-1,2-diyl, -CF2-, or -CFH-; ring A1 to ring A4 represent cyclohexane-1,4-diyl or 1,4-phenylene, but at least one of the ring A3 and ring A4 represents 2,3-difluoro-1,4-phenylene; Z1, Z2, and Z3 represent single bond, -(CH2)p-, -CO2-, -CF2O-, or -CH2O-; p is an integer of 2 to 4; and m and n are 0 or 1.

  本发明旨在提供具有负的、大的介电各向异性值和小的光学各向异性值的液晶化合物；包含该化合物的液晶组合物；以及使用该液晶组合物制造的液晶显示设备；该液晶化合物具有 2,3-二氟苯基分子，并由通式 (1) 表示 其中 Ra 和 Rb 代表具有 1 至 10 个碳原子的烷基或烷氧基，但至少 Ra 和 Rb 中的一个或多个亚甲基被环丙烷-1,2-二基、-CF2-或-CFH-取代；环 A1 至环 A4 代表环己烷-1,4-二基或 1,4-亚苯基，但环 A3 和环 A4 中至少有一个代表 2,3-二氟-1,4-亚苯基； Z1、Z2 和 Z3 代表单键、-(CH2)p-、-CO2-、-CF2O-或- O-；p 为 2 至 4 的整数；m 和 n 为 0 或 1。
• LIQUID CRYSTALLINE COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT
  申请人：Chisso Corporation

  公开号：EP2199270A1

  公开（公告）日：2010-06-23

  The invention provides a liquid crystal compound having stability to heat, light and so forth, a wide temperature range of a nematic phase, a small viscosity, a suitable optical anisotropy, a suitable elastic constant K33, a suitable and negative dielectric anisotropy, and an excellent compatibility with other liquid crystal compounds. The invention provides a liquid crystal composition containing the compound described above and having stability to heat, light and so forth, a small viscosity, a suitable optical anisotropy, a suitable and negative dielectric anisotropy, a suitable elastic constant K33, a low threshold voltage, a high maximum temperature of a nematic phase, and a low minimum temperature of the nematic phase. The invention also provides a liquid crystal display device having a short response time, a small power consumption, a low driving voltage, and a large contrast, and containing the composition described above which can be used in a large temperature range. For example, a liquid crystal compound having four or more rings in which the central ring has 2,3-difluorophenoxy such as trans-4'-[2,3-difluoro-4-(trans-4-propylcyclohexyl)phenoxymethyl]-trans-4-pentylbicyclohexyl is provided. Further provided is a liquid crystal composition containing the compound, and a liquid crystal display device using this liquid crystal composition.

  本发明提供了一种液晶化合物，它具有对热、光等的稳定性，向列相温度范围宽， 粘度小，适当的光学各向异性，适当的弹性常数 K33，适当的负介电各向异性，以及与 其他液晶化合物的良好兼容性。本发明提供了一种含有上述化合物的液晶组合物，该组合物具有对热、光等的稳定性、较小的粘度、适当的光学各向异性、适当的负介电各向异性、适当的弹性常数 K33、较低的阈值电压、向列相的最高温度较高以及向列相的最低温度较低。 本发明还提供了一种液晶显示装置，其响应时间短、功耗小、驱动电压低、对比度大，且含有上述成分，可在较大温度范围内使用。 例如，提供了一种具有四个或四个以上环的液晶化合物，其中中心环具有 2,3-二氟苯氧基，例如反式-4'-[2,3-二氟-4-（反式-4-丙基环己基）苯氧基甲基]-反式-4-戊基二环己基。此外，还提供了一种含有该化合物的液晶组合物，以及一种使用该液晶组合物的液晶显示设备。
• LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT
  申请人：JNC Corporation

  公开号：EP3275973A1

  公开（公告）日：2018-01-31

  Subject The subject is to provide a liquid crystal composition that includes a polymerizable compound (or polymer) and a polar compound, where the homeotropic alignment of liquid crystal molecules can be achieved by the action of these compounds, and a liquid crystal display device including this composition. This composition satisfies at least one of characteristics such as a high maximum temperature, a low minimum temperature, a small viscosity, a suitable optical anisotropy, a large positive dielectric anisotropy, a large specific resistance, a high stability to ultraviolet light or heat or a large elastic constant, or is suitably balanced regarding at least two of the characteristics. The means concerns a nematic liquid crystal composition that has positive dielectric anisotropy and that includes a polymerizable compound as an first additive and a polar compound as a second additive, and the composition may include a specific liquid crystal compound having a large positive dielectric anisotropy and a specific liquid crystal compound having a high maximum temperature or a small viscosity, and concerns a liquid crystal display device including the composition.

  主题 本课题旨在提供一种液晶组合物，其中包括一种可聚合化合物（或聚合物）和一种极性化合物，通过这些化合物的作用可实现液晶分子的各向同性排列，并提供一种包括这种组合物的液晶显示装置。这种组合物至少满足以下一种特性，如最高温度高、最低温度低、粘度小、光学各向异性合适、正介电各向异性大、比电阻大、对紫外线或热的稳定性高或弹性常数大，或至少在其中两种特性方面适当平衡。 该手段涉及一种具有正介电常数的向列液晶组合物，该组合物包括作为第一添加剂的可聚合化合物和作为第二添加剂的极性化合物，该组合物可包括具有较大正介电常数的特定液晶化合物和具有较高最高温度或较小粘度的特定液晶化合物，还涉及一种包括该组合物的液晶显示设备。
• SPONTANEOUS ORIENTATION AID FOR LIQUID CRYSTAL COMPOSITION, COMPOUND SUITABLE FOR SAID SPONTANEOUS ORIENTATION AID, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT
  申请人：DIC Corporation

  公开号：EP3467073A1

  公开（公告）日：2019-04-10

  The present invention provides a spontaneous orientation aid for a liquid crystal composition, containing one kind or two or more kinds of a compound having a partial structure represented by the general formula (i), wherein Zi1 represents a single bond, etc.; Ai1 represents a divalent 6-membered aromatic group, etc.; mi1 represents an integer of 1 to 5; and Ki1 represents a structure represented by any of the following formulae (K-1) to (K-8), wherein WK1 represents a methine group, etc.; XK1 and YK1 each represent -CH2-, etc.; ZK1 represents an oxygen atom, etc.; and UK1, VK1, and SK1 each represent a methine group, etc.:

  本发明提供了一种液晶组合物的自发定向助剂，该液晶组合物含有一种或两种或多种具有通式(i)所代表的部分结构的化合物，其中Zi1代表单键等；Ai1代表二价6元芳香基团等；mi1代表1至5的整数；Ki1代表下式(K-1至(K-8)中的任一式所代表的结构，其中WK1代表甲基等。mi1 代表 1 至 5 的整数；以及 Ki1 代表下式（K-1）至（K-8）中任一式所代表的结构，其中 WK1 代表甲基等；XK1 和 YK1 各自代表-CH2-等；ZK1 代表氧原子等；以及 UK1、VK1 和 SK1 各自代表甲基等：