4,4-bis-(4-hydroxy-3,5-dimethyl-phenyl)-valeric acid | 102472-32-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4,4-bis-(4-hydroxy-3,5-dimethyl-phenyl)-valeric acid
• 英文别名: 4,4-Bis-(4-hydroxy-3,5-dimethyl-phenyl)-valeriansaeure；4,4-Bis(4-hydroxy-3,5-dimethylphenyl)pentanoic acid
• CAS: 102472-32-2
• 化学式: C₂₁H₂₆O₄
• 分子量: 342.435
• InChiKey: BKXARXNEOUYVGV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.8
• 重原子数：
  25
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  77.8
• 氢给体数：
  3
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  2,6-二甲基苯酚 、 乙酰丙酸 在 盐酸 、 溶剂黄146 作用下， 生成 4,4-bis-(4-hydroxy-3,5-dimethyl-phenyl)-valeric acid
  参考文献：
  名称：

  Acid-Catalyzed Condensation of Phenols and Keto Acids

  摘要：

  DOI：

  10.1021/jo01101a016

文献信息

• Method for the preparation of aromatic chloroformates
  申请人：Davis Charles Gary

  公开号：US20060293535A1

  公开（公告）日：2006-12-28

  A method for preparing an aromatic chloroformate comprising, introducing a mixture of at least one aromatic hydroxyl compound, phosgene, at least one solvent, and at least one organic base into a flow reactor to obtain a unidirectionally flowing reaction mixture. The unidirectionally flowing reaction mixture is maintained at a temperature between about 0° C. and about 60° C. to produce a single product stream comprising an aromatic chloroformate.

  一种制备芳香氯甲酸酯的方法包括，将至少一种芳香羟基化合物、光气、至少一种溶剂和至少一种有机碱的混合物引入流动反应器中，以获得单向流动的反应混合物。将单向流动的反应混合物保持在约0°C至约60°C的温度下，以产生包含芳香氯甲酸酯的单一产物流。
• Method for the preparation of aliphatic chloroformates
  申请人：Davis Charles Gary

  公开号：US20060084822A1

  公开（公告）日：2006-04-20

  A method for preparing an aliphatic chloroformate comprising, introducing a mixture of at least one aliphatic hydroxyl compound, phosgene, at least one solvent, and optionally at least one organic base into a flow reactor to obtain a unidirectional flowing reaction mixture. The at least one aliphatic hydroxyl compound comprises at least one aliphatic hydroxyl group. The unidirectional flowing reaction mixture is maintained at a temperature between about 0° C. and about 60° C. to produce a single product stream comprising an aliphatic chloroformate.

  制备脂肪基氯甲酸酯的方法包括，将至少一种脂肪基羟基化合物、光气、至少一种溶剂以及可选的至少一种有机碱的混合物引入流动反应器中，以获得单向流动的反应混合物。至少一种脂肪基羟基化合物包括至少一种脂肪基羟基。将单向流动的反应混合物保持在约0°C至约60°C的温度下，以产生包含脂肪基氯甲酸酯的单一产物流。
• Method for preparation of salts of hydroxy-substituted aromatic compounds
  申请人：Silva Manio James

  公开号：US20060224024A1

  公开（公告）日：2006-10-05

  A method for preparing a metal salt of a hydroxy-substituted aromatic compound is described. The method comprises contacting in an aqueous medium at least one hydroxy-substituted aromatic compound with a base comprising a metal cation to provide a mixture comprising water and a metal salt of said hydroxy-substituted aromatic compound. The aqueous metal salt is then contacted with a substantially water-immiscible solvent at a temperature greater than the boiling point of water at the prevailing pressure to provide a slurry comprising the metal salt of the hydroxy-substituted aromatic compound and a vapor stream comprising the water-immiscible solvent and water. The components of the vapor stream are separated using a vapor handling system comprising a partial reflux condenser to provide a water-rich component and a water immiscible solvent-rich component.

  本文描述了一种制备含羟基芳香化合物金属盐的方法。该方法包括在水介质中接触至少一种含羟基芳香化合物与包含金属阳离子的碱基，以提供包含水和所述含羟基芳香化合物金属盐的混合物。然后将水性金属盐与一种温度高于当前压力下水的沸点的基本不溶于水的溶剂接触，以提供包含含羟基芳香化合物金属盐和蒸汽流的悬浮液，其中蒸汽流包括基本不溶于水的溶剂和水。使用蒸汽处理系统分离蒸汽流的组分，包括部分回流冷凝器，以提供富含水的组分和基本不溶于水的溶剂富集组分。
• Method of improving abrasion resistance of plastic article using functionalized polymers and article produced thereby
  申请人：Tamaki Ryo

  公开号：US20070085242A1

  公开（公告）日：2007-04-19

  The invention includes embodiments that relate to a method of improving the abrasion resistance of a plastic article. The method comprises: (a) providing a composition comprising at least one e-beam active thermoplastic polymeric material; (b) forming an article from the composition of step (a); and (c) exposing the article formed in step (b) to an electron beam source. The invention also includes embodiments that relate to an article comprising an abrasion resistant surface.

  该发明涉及改善塑料制品耐磨性的方法。该方法包括：(a)提供一个组成物，包括至少一种电子束活性热塑性聚合物材料；(b)从步骤(a)的组成物形成一件制品；以及(c)将在步骤(b)中形成的制品暴露于电子束源。该发明还涉及一种具有耐磨表面的制品。
• Benzimidazole-containing sulfonated polyethersulfones
  申请人：Hung Joyce

  公开号：US20070100131A1

  公开（公告）日：2007-05-03

  Sulfonated polyethersulfones and polymer compositions comprising sulfonated polyethersulfones and at least one inorganic heteropolyacid are useful as proton exchange membranes for fuel cells. The polyethersulfones include structural units derived from at least one biphenol monomer and a monomer of formula I wherein X is O, S or NR 1 ; Y is N or CR 5 ; R 1 , R 2 , R 3 and R 4 are independently hydrogen, alkyl, substituted alkyl, aryl, substituted aryl, alkylaryl, substituted alkylaryl, arylalkyl or substituted arylalkyl, or R 3 and R 4 , taken together, form a 5- or 6-membered substituted or unsubstituted aliphatic or aromatic ring; R 5 is hydrogen, alkyl, substituted alkyl, aryl, substituted aryl, alkylaryl, substituted alkylaryl, arylalkyl or substituted arylalkyl; and L is a direct bond or a divalent aromatic linker containing 6-12 carbons

  磺化聚醚砜和包含磺化聚醚砜和至少一种无机杂多酸的聚合物组成物可用作燃料电池的质子交换膜。聚醚砜包括从至少一种联苯单体和式I的单体导出的结构单元，其中X为O、S或NR1；Y为N或CR5；R1、R2、R3和R4独立地为氢、烷基、取代烷基、芳基、取代芳基、烷基芳基、取代烷基芳基、芳基烷基或取代芳基烷基，或R3和R4一起形成一个5-或6-成员的取代或未取代的脂肪族或芳香族环；R5为氢、烷基、取代烷基、芳基、取代芳基、烷基芳基、取代烷基芳基、芳基烷基或取代芳基烷基；L为直接键或含有6-12个碳的二价芳香链节。