1-adamantylcarbonyloxymethyl iodide | 106518-37-0

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 1-adamantylcarbonyloxymethyl iodide
• 英文别名: Iodomethyl adamantane-1-carboxylate
• CAS: 106518-37-0
• 化学式: C₁₂H₁₇IO₂
• 分子量: 320.17
• InChiKey: INIMWWIIVMLOMK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  15
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.92
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  1-adamantylcarbonyloxymethyl iodide 、 sodium(1S,5R,6S)-6-((1R)-1-hydroxyethyl)-2-(7-methanesulfonylimidazo[5,1-b]thiazol-2-yl)-1-methyl-1-carbapen-2-em-3-carboxylate 生成 1-Adamantylcarbonyloxymethyl(1S,5R,6S)-6-((1R)-1-hydroxyethyl)-2-(7-methanesulfonyl-imidazo[5,1-b]thiazol-2-yl)-1-methyl-1-carbapen-2-em-3-carboxylate
  参考文献：
  名称：

  Carbapenem derivatives

  摘要：

  公开了一种新的碳青霉烯衍生物，其在碳青霉烯环的2位置具有取代的咪唑[5,1-b]噻唑基团，对产生β-内酰胺酶的细菌、耐甲氧西林金黄色葡萄球菌(MRSA)、抗假单胞菌属铜绿假单胞菌、肺炎链球菌(PRSP)、肠球菌和流感具有高的抗菌活性，并对DHP-1具有高稳定性。根据本发明，提供了一种由公式(I)表示的化合物，或其药理上可接受的盐，或其碳青霉烯环上3位置的酯。

  公开号：

  US06458780B1

文献信息

• SALT, ACID GENERATOR, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：US20190137873A1

  公开（公告）日：2019-05-09

  The present invention can provide a salt and a resist composition including the salt, capable of producing a resist pattern with satisfactory line edge roughness (LER). A salt represented by formula (I): wherein R 1 and R 2 each represent a chain hydrocarbon group which may have a substituent, an alicyclic hydrocarbon group which may have a substituent or an aromatic hydrocarbon group which may have a substituent, or R 1 and R 2 are bonded each other to form a ring together with sulfur atoms to which they are bonded, R 3 , R 4 and R 5 each independently represent a hydrogen atom, a fluorine atom or a hydrocarbon group having 1 to 12 carbon atoms, —CH 2 — included in the hydrocarbon group may be replaced by —O— or —CO—, and A − represents a counter anion.

  本发明提供了一种盐和包括该盐的抗蚀剂组合物，能够产生具有令人满意的线边粗糙度（LER）的抗蚀图案。该盐由式（I）表示：其中R1和R2各代表可能具有取代基的链烃基，可能具有取代基的脂环烃基或可能具有取代基的芳香烃基，或者R1和R2彼此相连以形成与它们结合的硫原子一起的环，R3、R4和R5各自独立地表示氢原子、氟原子或具有1至12个碳原子的烃基，烃基中包括的—CH2—可以被—O—或—CO—所取代，A-表示反离子。
• SALT AND PHOTORESIST COMPOSITION CONTAINING THE SAME
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：US20180065925A1

  公开（公告）日：2018-03-08

  A salt represented by formula (I): wherein R 1 and R 2 independently each represent a C6-C18 unsubstituted or substituted aromatic hydrocarbon group, X 1 represents a C1-C12 divalent aliphatic saturated hydrocarbon group in which a methylene group can be replaced by an oxygen atom or a carbonyl group, and A − represents an organic anion.

  一种由化学式(I)表示的盐：其中R1和R2分别独立地代表C6-C18未取代或取代的芳香烃基，X1代表C1-C12二价脂肪饱和碳氢烃基，其中一个亚甲基基团可被氧原子或羰基取代，A−代表有机阴离子。
• CARBOXYLATE, QUENCHER, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：US20210371377A1

  公开（公告）日：2021-12-02

  A carboxylate represented by formula (I), a quencher and a resist composition including the same: wherein R 1 , R 2 and R 3 each represent a halogen atom, an alkyl fluoride group or a hydrocarbon group which may have a substituent, —CH 2 — included in the hydrocarbon group may be replaced by —O—, —CO—, —S— or —SO 2 —, m1 represents an integer of 0 to 5, m2 represents an integer of 0 to 4, m3 represents an integer of 0 to 3, and X 1 represents a single bond, —CH 2 —, —O—, —S—, —CO—, —SO— or —SO 2 —.

  一种以式(I)表示的羧酸盐、淬灭剂和包括该羧酸盐的抗蚀组合物：其中，R1、R2和R3分别表示卤素原子、氟代烷基或烃基，该烃基可以有取代基，烃基中包括的—CH2—可以被—O—、—CO—、—S—或—SO2—替换，m1表示0到5的整数，m2表示0到4的整数，m3表示0到3的整数，X1表示单键、— —、—O—、—S—、—CO—、—SO—或—SO2—。
• Novel carbapenem derivatives
  申请人：——

  公开号：US20030149016A1

  公开（公告）日：2003-08-07

  Disclosed is a novel carbapenem derivative having a substituted imidazo[5,1-b]thiazole group at the 2-position on the, carbapenem ring have high anti-microbial activities against &bgr;-lactamase producing bacteria, MRSA, resistant- Pseudomonas aeruginosa , PRSP, enterococci, and influenza, and high stabilities to DHP-1. According to the present invention, there is provided a compound represented by the formula (I), or a pharmacologically acceptable salt thereof or an ester at the 3-position on the carbapenem ring thereof: 1

  本发明公开了一种新型碳青霉烯衍生物，其在碳青霉烯环上的2位上具有取代咪唑[5,1-b]噻唑基团，对β-内酰胺酶产生的细菌、MRSA、耐药性假单胞菌、PRSP、肠球菌和流感病毒具有高抗菌活性，并对DHP-1具有高稳定性。根据本发明，提供了由式(I)表示的化合物，或其在碳青霉烯环上的3位处的药理学上可接受的盐或酯：1。
• NOVEL CARBAPENEM DERIVATIVES
  申请人：Meiji Seika Kaisha, Ltd.

  公开号：EP1101766A1

  公开（公告）日：2001-05-23

  Disclosed is a novel carbapenem derivative having a substituted imidazo[5,1-b]thiazole group at the 2-position on the carbapenem ring have high anti-microbial activities against β-lactamase producing bacteria, MRSA, resistant-Pseudomonas aeruginosa, PRSP, enterococci, and influenza, and high stabilities to DHP-1. According to the present invention, there is provided a compound represented by the formula (I), or a pharmacologically acceptable salt thereof or an ester at the 3-position on the carbapenem ring thereof:

  本发明公开了一种新型碳青霉烯类衍生物，该衍生物的碳青霉烯环上 2 位具有取代的咪唑并[5,1-b]噻唑基团，对产β-内酰胺酶细菌、MRSA、耐药铜绿假单胞菌、PRSP、肠球菌和流感具有高抗微生物活性，对 DHP-1 具有高稳定性。根据本发明，提供了一种由式（I）代表的化合物，或其药理学上可接受的盐，或其碳青霉烯环上 3 位的酯：