N-acetyl-D-tyrosine butyl ester

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: N-acetyl-D-tyrosine butyl ester
• 英文别名: N-Acetyltyrosine, butyl ester；butyl (2R)-2-acetamido-3-(4-hydroxyphenyl)propanoate
• 化学式: C₁₅H₂₁NO₄
• 分子量: 279.336
• InChiKey: CTJGJXAREXCTJW-CQSZACIVSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  20
• 可旋转键数：
  8
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.47
• 拓扑面积：
  75.6
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  N-acetyl-DL-tyrosine butyl ester 生成 N-acetyl-D-tyrosine butyl ester
  参考文献：
  名称：

  Enantioselective hydrolytic reactions of rice bran lipase (RBL): a frist report

  摘要：

  Enantioselectivity has been observed in the hydrolysis of racemic N-acetyl amino acid esters with rice bran lipase (RBL). The enzyme shows selectivity towards the (S)-enantiomer. Products with high enantiomeric excess (e.e. > 99%) are obtained depending upon the hydrophobicity of the amino acid as well as that of the leaving group. (C) 1997 Elsevier Science Ltd.

  DOI：

  10.1016/s0957-4166(97)00241-3

文献信息

• Enantioselective hydrolytic reactions of rice bran lipase (RBL): a frist report
  作者：N.W. Fadnavis、Vasudev Jadhav

  DOI：10.1016/s0957-4166(97)00241-3

  日期：1997.7

  Enantioselectivity has been observed in the hydrolysis of racemic N-acetyl amino acid esters with rice bran lipase (RBL). The enzyme shows selectivity towards the (S)-enantiomer. Products with high enantiomeric excess (e.e. > 99%) are obtained depending upon the hydrophobicity of the amino acid as well as that of the leaving group. (C) 1997 Elsevier Science Ltd.