防老剂AW | 5891-53-2

• 物质功能分类: 催化剂及助剂 - 防老剂
• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 防老剂AW
• 英文名称: Glu-lys
• 英文别名: (2S)-6-amino-2-[[(2S)-2-amino-4-carboxybutanoyl]amino]hexanoic acid
• CAS: 5891-53-2
• 化学式: C₁₁H₂₁N₃O₅
• 分子量: 275.3
• InChiKey: BBBXWRGITSUJPB-YUMQZZPRSA-N

物化性质

• 熔点：
  >150 °C (decomp)(Solv: methanol (67-56-1))
• 沸点：
  611.9±55.0 °C(Predicted)
• 密度：
  1.290±0.06 g/cm3(Predicted)
• 溶解度：
  可溶于酸水溶液（少量），水（少量，超声处理）
• 物理描述：
  Solid

计算性质

• 辛醇/水分配系数(LogP)：
  -6.3
• 重原子数：
  19
• 可旋转键数：
  10
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.73
• 拓扑面积：
  156
• 氢给体数：
  5
• 氢受体数：
  7

安全信息

• 海关编码：
  2924199090

制备方法与用途

用途：主要用作橡胶防老化，尤其在防止由臭氧引起的龟裂方面表现出色。它特别适用于动态条件下使用的橡胶制品。

文献信息

• Topical composition containing specific flavanones
  申请人：UNILEVER PLC

  公开号：EP0774249A2

  公开（公告）日：1997-05-21

  Cosmetic compositions containing combinations of flavanones:eriodictyol and/or taxifolin combined with taxifolin and/or hesperetin. Alternatively, a flavanone is combined with a short-chain lipid. The compositions enhance keratinocyte differentiation in skin, thus decreasing skin dryness and decreasing appearance of wrinkles.

  含有黄酮类化合物的化妆品组合：eriodictyol和/或taxifolin与taxifolin和/或hesperetin的组合。或者，黄酮与短链脂结合。这些组合物能促进皮肤角质细胞的分化，从而减轻皮肤干燥，减少皱纹的出现。
• COMPOSITION FOR LOCAL ANESTHESIA
  申请人：Showa Yakuhin Kako Co. Ltd

  公开号：EP0858803A1

  公开（公告）日：1998-08-19

  A composition for local anesthesia which comprises (A) lidocaine, (B) a catecholamine such as epinephrine in an amount of, for example, 1/200,000 (g/ml) based on the volume of the composition, and (C) one or more amino acids such as glycine, glutamic acid, and L-glutamic acid-L-lysine or one or more hydroxycarboxylic acids such as lactic acid, glycolic acid, and citric acid, which has a duration suitable for short-time dental operations such as tooth extraction and excellent storage stability.

  一种用于局部麻醉的组合物，它包括(A)利多卡因，(B)儿茶酚胺，如肾上腺素，其用量以组合物体积为基准，例如为1/200,000(克/毫升)，以及(C)一种或多种氨基酸，如甘氨酸、谷氨酸、L-谷氨酸-L-赖氨酸或一种或多种羟基羧酸，如乳酸、乙醇酸和柠檬酸、(C) 一种或多种氨基酸，如甘氨酸、谷氨酸和 L-谷氨酸-L-赖氨酸，或一种或多种羟基羧酸，如乳酸、乙醇酸和柠檬酸。
• Use of secoiridoids, preferably oleuropein, for cross-linking biopolymers
  申请人：NIZO food research

  公开号：EP1489135A1

  公开（公告）日：2004-12-22

  The invention relates to the use of a secoiridoid-containing substance as a nontoxic cross-linking agent for the cross-linking of appropriate compounds including biopolymers, such as polypeptides and polysaccharides. Such biopolymers are particularly suitable in the production of food, feed, pharmaceutical and biomedical preparations, home and care products, and the like. Preferably, the cross-linking agent comprises an aglycone from a glycoside selected from the group of oleuropein, demethyloleuropein, verbascoside, ligustroside, and cornoside. Of these, oleuropein is preferred.

  本发明涉及一种含猿猴苷的物质作为无毒交联剂，用于交联适当的化合物，包括生物聚合物，如多肽和多糖。这类生物聚合物尤其适用于食品、饲料、药物和生物医学制剂、家居和护理产品等的生产。优选地，交联剂包括来自选自油菜素、去甲基油菜素、马鞭草苷、藁本苷和矢车菊苷的苷元的苷元酮。其中，油菜素是首选。
• HAIR TREATMENT COMPOSITION AND HAIR COSMETIC FOR DAMAGED HAIR
  申请人：Meiji Seika Kaisha, Ltd.

  公开号：EP1602354A1

  公开（公告）日：2005-12-07

  The present invention intends to provide a composition for hair treatment containing γ-polyglutamic acid or a salt thereof, a hair cosmetic for damaged hair containing such a composition, and their uses. The composition for hair treatment containing γ-polyglutamic acid or a salt thereof and the hair cosmetic for damaged hair of the present invention have excellent improvement effects on the strength and frictional force of hair, so that they can provide tension, elasticity, or the like to damage hair to prevent or alleviate split hair and broken hair as well as improvements in combing and touch. Furthermore, they also exert effects of moisture retention inherent to γ-polyglutamic acid or a salt thereof, preventing or improving effects on the generation of dandruff on the basis of such effects, preventing effects on the feeling of stickiness or creak, and various effectiveness including appropriate residual tendency to hair in a simultaneous manner, respectively.

  本发明旨在提供一种含有γ-聚谷氨酸或其盐的头发治疗组合物、一种含有这种组合物的用于受损头发的护发化妆品及其用途。本发明的含有γ-聚谷氨酸或其盐的头发治疗组合物和用于受损头发的护发化妆品对头发的强度和摩擦力有很好的改善效果，因此它们可以为受损头发提供张力、弹性等，以防止或减轻头发分叉和断裂，并改善梳理和触感。此外，它们还能分别发挥γ-聚谷氨酸或其盐固有的保湿效果、在此基础上防止或改善头皮屑产生的效果、防止粘腻感或吱吱作响的效果，以及包括同时对头发产生适当残留倾向在内的各种功效。
• HAIR GROWTH COMPOSITION
  申请人：Ajinomoto Co., Inc.

  公开号：EP2042157A1

  公开（公告）日：2009-04-01

  The present invention provides a hair growth agent having novel action mechanism and a hair growth composition containing the agent. Specifically, the present invention provides a novel hair growth composition containing one or more kinds of epsilon-N-(gamma-glutamyl)lysine or a salt thereof.

  本发明提供了一种具有新型作用机制的生发剂和一种含有该生发剂的生发组合物。具体来说，本发明提供了一种含有一种或多种epsilon-N-（γ-谷氨酰）赖氨酸或其盐的新型生发组合物。