Benzyl Violet 4B | 1694-09-3

• 物质功能分类: 染料及颜料 - 染料 - 酸性染料
• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Benzyl Violet 4B
• 英文别名: sodium;3-[[4-[(4-dimethylazaniumylidenecyclohexa-2,5-dien-1-ylidene)-[4-[ethyl-[(3-sulfonatophenyl)methyl]amino]phenyl]methyl]-N-ethylanilino]methyl]benzenesulfonate
• CAS: 1694-09-3
• 化学式: C39H40N3NaO6S2
• 分子量: 733.9
• InChiKey: AXMCIYLNKNGNOT-UHFFFAOYSA-M

物化性质

• 熔点：
  245-250°C
• 溶解度：
  可溶于DMSO（少许）、甲醇（少许）
• 物理描述：
  Benzyl violet 4b is a fine black powder. (NTP, 1992)
• 颜色/状态：
  FINE POWDER
• 稳定性/保质期：

  在常温常压下保持稳定。

计算性质

• 辛醇/水分配系数(LogP)：
  3.19
• 重原子数：
  51
• 可旋转键数：
  10
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.21
• 拓扑面积：
  141
• 氢给体数：
  0
• 氢受体数：
  8

ADMET

毒理性

• 致癌性证据

没有关于人类的数据。有充分的证据表明对动物具有致癌性。总体评估：2B组：该物质可能对人类具有致癌性。

No data are available in humans. Sufficient evidence of carcinogenicity in animals. OVERALL EVALUATION: Group 2B: The agent is possibly carcinogenic to humans.

来源:Hazardous Substances Data Bank (HSDB)

毒理性

• 致癌物分类

国际癌症研究机构致癌物：苯偶氮基紫4B

IARC Carcinogenic Agent:Benzyl violet 4B

来源:International Agency for Research on Cancer (IARC)

毒理性

• 致癌物分类

国际癌症研究机构（IARC）致癌物分类：2B组：可能对人类致癌

IARC Carcinogenic Classes:Group 2B: Possibly carcinogenic to humans

来源:International Agency for Research on Cancer (IARC)

毒理性

• 致癌物分类

国际癌症研究机构专论：第16卷（1978年）一些芳香胺及其相关硝基化合物 - 染发剂、着色剂和杂项工业化学品

IARC Monographs:Volume 16: (1978) Some Aromatic Amines and Related Nitro Compounds – Hair Dyes, Colouring Agents and Miscellaneous Industrial Chemicals

来源:International Agency for Research on Cancer (IARC)

毒理性

• 副作用

国际癌症研究机构致癌物-第3类：化学品无法被国际癌症研究机构分类。

IARC Carcinogen - Class 3: Chemicals are not classifiable by the International Agency for Research on Cancer.

来源:Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

吸收、分配和排泄

苯甲基紫4B表现出高血浆蛋白结合能力。/在实验系统中/

BENZYL VIOLET 4B EXHIBITS HIGH PLASMA PROTEIN BINDING. /IN EXPTL SYSTEMS/

来源:Hazardous Substances Data Bank (HSDB)

吸收、分配和排泄

在大鼠和狗中进行的口服苯基紫4B研究显示，只有少量染料（少于5%）被吸收并排出，主要在粪便中。

STUDIES IN RATS & DOGS WITH ORAL ADMIN OF BENZYL VIOLET 4B INDICATES THAT ONLY SMALL AMT OF THE DYE (LESS THAN 5%) ARE ABSORBED & EXCRETED, MAINLY IN THE FECES.

来源:Hazardous Substances Data Bank (HSDB)

吸收、分配和排泄

颜色在口服时几乎不被吸收；24小时后从胆汁中回收的剂量仅为0.89%。如果静脉给药，会通过胆汁迅速排泄。

COLOR HARDLY ABSORBED WHEN GIVEN ORALLY; ONLY 0.89% OF DOSE RECOVERED FROM BILE AFTER 24 HR. RAPIDLY EXCRETED THROUGH BILE IF GIVEN IV.

来源:Hazardous Substances Data Bank (HSDB)

吸收、分配和排泄

在大鼠肝脏、肾脏、腹部肌肉和血清中的颜色水平范围在1-3微克/克组织中，这些大鼠被喂食含有5%紫罗兰色的饮食，持续8周。

LEVELS OF COLOR IN LIVER, KIDNEY, ABDOMINAL MUSCLE & BLOOD SERUM RANGED 1-3 MUG/G OF TISSUE IN RATS FED DIET CONTAINING 5% VIOLET/8 WK.

来源:Hazardous Substances Data Bank (HSDB)

安全信息

• 危险等级：
  6.1
• 危险品标志：
  Xn
• 安全说明：
  S36/37,S53
• 危险类别码：
  R40
• WGK Germany：
  1
• 危险品运输编号：
  UN 2811
• RTECS号：
  BQ1140000
• 包装等级：
  III
• 危险类别：
  6.1
• 危险性防范说明：
  P201,P202,P280,P308+P313,P405,P501
• 危险性描述：
  H350

制备方法与用途

简介

酸性紫49是一种化工颜料，主要应用于羊毛、丝绸和锦纶的染色。由于其具有一定的致癌性，因此在使用时需严格控制其在这些纤维中的添加量以及废水、粉尘中的含量。目前尚未有可用于检测的酸性紫49标准样品报道。

用途

主要应用于半羊毛染色及羊毛、丝绸和锦纶的染色。

反应信息

• 作为反应物：
  描述：

  disodium;(3Z)-5-acetamido-4-oxo-3-(phenylhydrazinylidene)naphthalene-2,7-disulfonate 、 Benzyl Violet 4B 、 Naphthol yellow S, 98% 生成 sodium;4-hydroxy-3-[(2Z)-2-(2-oxonaphthalen-1-ylidene)hydrazinyl]benzenesulfonate
  参考文献：
  名称：

  Negative dye-containing curable composition, color filter and method of producing the same

  摘要：

  一种含有负性染料的可固化组合物，包括：（A）有机溶剂可溶的染料，（B）光聚合引发剂，（C）自由基可聚合单体，和（D）有机溶剂，其中组合物还包括（X）一种不同于有机溶剂可溶染料（A）的无机金属盐，且无机金属盐（X）的含量相对于组合物的总固体含量为0.1质量％或更少。

  公开号：

  US20070072955A1

文献信息

• CURABLE COMPOSITION, COLOR FILTER, AND MANUFACTURING METHOD OF THE SAME
  申请人：Nakashima Taeko

  公开号：US20100045905A1

  公开（公告）日：2010-02-25

  A curable composition including (A) a compound which has a plurality of ethylenically unsaturated double bonds and secondary hydroxyl groups, (B) a photopolymerization initiator, and (C) a coloring agent, is used to provide a curable composition which exhibits excellent storage stability such as dispersion stability even in the case where a coloring agent is included at high concentration, highly sensitive curability by exposure, high adhesiveness to the surface of a hardening material in a curing region when applied in forming patterns on the surface of the hardening material, excellent uncured region removability, and excellent pattern formability; a color filter having colored patterns, which is formed by using the curable composition and has excellent resolution and adhesiveness to the support; and a manufacturing method of the coloring filter with high productivity.

  一种可治愈的组合物包括（A）具有多个乙烯基不饱和双键和次级羟基的化合物，（B）光聚合引发剂和（C）着色剂，用于提供一种可治愈的组合物，即使在高浓度下包含着色剂的情况下也表现出优异的储存稳定性，如分散稳定性，通过曝光高度敏感的可固化性，在硬化材料表面形成图案时具有高粘附性，在未固化区域具有优异的可去除性和优异的图案成形性；使用可治愈的组合物形成的具有着色图案的彩色滤光片，具有优异的分辨率和对支撑物的粘附性；以及具有高生产率的着色滤光片制造方法。
• HAIR DYE CONTAINING ONE OR MORE EDIBLE OR COSMETIC COLORS
  申请人：CHUANG KUO SHENG

  公开号：US20120141398A1

  公开（公告）日：2012-06-07

  This invention discloses a hair dye and a hair dyeing method using a dye mainly made of natural colors (used in food and cosmetics), synthetic colors (used in food and cosmetics), and cosmetic colors. The hair dye can be applied for dyeing hair and skin at the same time according to the keratin-like structure of the hair and skin. The hair dye can be manufactured in a form of a hair dye cream, a hair dye lotion, a frost hair dye, a hair dye gel, a hair dye ointment, a hair dye shampoo, a foam type hair dye, or a spray type hair dye. After the hair dye is combined with a perm agent, a dyeing and perming product is produced for dyeing and perming hair all at one time. The natural colors (used in food and cosmetics), synthetic colors (used in food and cosmetics) and cosmetic colors of the hair dye penetrate into the hair by different hair dyeing methods to achieve the hair dyeing effect, and permanent hair dye, semi-permanent hair dye and temporary hair dye are manufactured according to the depth that the color enters into the hair structure.
• Negative dye-containing curable composition, color filter and method of producing the same
  申请人：Fujimori Toru

  公开号：US20070072955A1

  公开（公告）日：2007-03-29

  A negative dye-containing curable composition, comprising: (A) an organic solvent-soluble dye, (B) a photopolymerization initiator, (C) a radical-polymerizable monomer, and (D) an organic solvent, wherein the composition contains further comprises (X) an inorganic metal salt that is different from the organic solvent-soluble dye (A), and the content of the inorganic metal salt (X) is 0.1 mass % or less with respect to the total solid content of the composition is provided.

  一种含有负性染料的可固化组合物，包括：（A）有机溶剂可溶的染料，（B）光聚合引发剂，（C）自由基可聚合单体，和（D）有机溶剂，其中组合物还包括（X）一种不同于有机溶剂可溶染料（A）的无机金属盐，且无机金属盐（X）的含量相对于组合物的总固体含量为0.1质量％或更少。