3-(3,6-Dichloro-carbazol-9-YL)-propane-1,2-diol

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: 3-(3,6-Dichloro-carbazol-9-YL)-propane-1,2-diol
• 英文别名: 3-(3,6-dichlorocarbazol-9-yl)propane-1,2-diol
• 化学式: C₁₅H₁₃Cl₂NO₂
• 分子量: 310.2
• InChiKey: HUEAREQFYNUIEN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  20
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  45.4
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  9-allyl-3,6-dichloro-carbazole 、 potassium permanganate 以50%的产率得到
  参考文献：
  名称：

  ZHEREBTSOV I. P.; LOPATINSKIJ V. P.; ROVKINA N. M.; MORDVINOVA I. N., IZV. VUZOV. XIMIYA I XIM. TEXNOL., 1980, 23, HO 8, 968-970

  摘要：

  DOI：

文献信息

• MODULATION OF K2P CHANNELS
  申请人：The Regents of the University of California

  公开号：US20160031814A1

  公开（公告）日：2016-02-04

  Disclosed herein inter alia are compositions and methods useful in the treatment of diseases, for example pain, neurodegeneration, or mood disorders, and for modulating the activity of a K 2P channel.

  在此公开的包括用于治疗疾病（例如疼痛、神经退行性疾病或情绪障碍）和调节K2P通道活性的组合物和方法。
• HIGH REFRACTIVE INDEX COMPOSITION
  申请人：Lalgudi Ramanathan S.

  公开号：US20130046054A1

  公开（公告）日：2013-02-21

  A high refractive index composition comprising a reaction product of one or more first organic compounds capable of undergoing polymerization and one or more second compounds with high refractive index, and the method of making and using the composition. A composition comprising an organic compound obtained by coupling two reactive groups (a) and (b), wherein a. the reactive group (a) is Y—(CH 2 )n-M(O—R) 3 , wherein R is CH 3 , C 2 H 5 , C 3 H 8 , C 4 H 10 ; and Y is —NH 2 , —COOH, —NCO, or epoxy; and wherein M is selected from the group consisting of Ti, Zr, V, Mg, Al, Mn, Sb, Ba, Ca, Ce, Si, and Sn; and b. the reactive group (b) is selected from the group consisting of carbazole, fluorene, imidazole with one or more functional groups selected from —OH, —NH 2 , —COOH, —NCO, -epoxy, -vinyl, -acrylic, -acyl, -alkyl, -halide, -amino, -ketone, -allyl, -allylic, -thiol, -isocyanate, and a mixture thereof; and the method of making and using the composition.
• US8883935B2
  申请人：——

  公开号：US8883935B2

  公开（公告）日：2014-11-11
• US9862684B2
  申请人：——

  公开号：US9862684B2

  公开（公告）日：2018-01-09
• [EN] MODULATION OF K2P CHANNELS<br/>[FR] MODULATION DE CANAUX K2P
  申请人：UNIV CALIFORNIA

  公开号：WO2014165307A2

  公开（公告）日：2014-10-09

  Disclosed herein inter alia are compositions and methods useful in the treatment of diseases, for example pain, neurodegeneration, or mood disorders, and for modulating the activity of a K2P channel.