2-(4-Ethylphenoxy)ethyl methanesulfonate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 2-(4-Ethylphenoxy)ethyl methanesulfonate
• 化学式: C₁₁H₁₆O₄S
• 分子量: 244.31
• InChiKey: ZIQAPOPYQLCCIC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  16
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  61
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  1'-[2-(4-Chlorophenoxy)ethyl]-6-methoxy-2,3,4,9-tetrahydrospiro[beta-carboline-1,3'-pyrrolidine] trifluoroacetate 、 2-(4-Ethylphenoxy)ethyl methanesulfonate 以to afford 0.0214 g的产率得到1'-[2-(4-ethylphenoxy)ethyl]-6-methoxy-2,3,4,9-tetrahydrospiro[β-carboline-1,3'-pyrrolidine]
  参考文献：
  名称：

  Beta-carbolines as growth hormone secretagogue receptor (GHSR) antagonists

  摘要：

  本发明涉及式（I）的化合物：其中R3-R8，X和Y如本文所述，制备该化合物的方法，包含该化合物的药物组合物，以及在预防或治疗与GHSR受体相关的疾病中使用该化合物和组合物。此类疾病的例子包括肥胖症和相关疾病，如2型糖尿病，血脂异常和代谢综合征，普拉德-威利综合征，心血管疾病，如动脉粥样硬化、心绞痛、心肌梗死和中风，肢端肥大症和癌症，特别是乳腺癌、肺癌、前列腺癌、甲状腺癌和内分泌腺垂体癌。

  公开号：

  US20050288316A1

文献信息

• PASTE COMPOSITION
  申请人：LEE Eun Sung

  公开号：US20100207077A1

  公开（公告）日：2010-08-19

  A paste composition comprises a dye containing a novel oligomeric compound with improved dispersion performance. The oligomeric compound comprises a tail structure consisting of hydrophilic and hydrophobic blocks and an amine or imidazole head structure. The paste composition can be used to prepare a semiconductor electrode of a solar cell. A semiconductor electrode produced using the paste composition and a solar cell fabricated using the semiconductor electrode exhibit greatly improved power conversion efficiency and superior processability.

  一种粘合剂组合物包括一种含有新型低聚化合物的染料，该低聚化合物具有改进的分散性能。该低聚化合物包括一个由亲水性和疏水性块组成的尾部结构和一个胺或咪唑头部结构。该粘合剂组合物可用于制备太阳能电池的半导体电极。使用该粘合剂组合物制备的半导体电极和使用该半导体电极制造的太阳能电池具有极大的功率转换效率和优异的加工性能。
• DISPERSANT COMPOUND AND METHOD FOR PREPARING THE SAME
  申请人：LEE Eun Sung

  公开号：US20070295957A1

  公开（公告）日：2007-12-27

  Disclosed herein are a novel oligomeric compound with improved dispersion performance and a method for preparing the same. The oligomeric compound comprises a tail structure consisting of hydrophilic and hydrophobic blocks and an amine or imidazole head structure. The dye containing the compound can be used to prepare a paste composition for a semiconductor electrode of a solar cell. A semiconductor electrode produced using the paste composition and a solar cell fabricated using the semiconductor electrode exhibit greatly improved power conversion efficiency and superior processability.
• US8470209B2
  申请人：——

  公开号：US8470209B2

  公开（公告）日：2013-06-25
• [EN] NOVEL BETA-CARBOLINES AS GROWTH HORMONE SECRETAGOGUE RECEPTOR (GHSR) ANTAGONISTS<br/>[FR] NOUVELLES CARBOLINES-BETA EN TANT QU'ANTAGONISTES DE RECEPTEUR DE SECRETAGOGUE D'HORMONE DE CROISSANCE
  申请人：BIOVITRUM AB

  公开号：WO2005048916A2

  公开（公告）日：2005-06-02

  The present invention relates to compounds of Formula (I): Formula (I) wherein R3-R8, X, and Y are as described herein, processes for preparing the compounds, pharmaceutical compositions comprising the compounds, and use of the compounds and compositions in the prophylaxis or treatment of a GHSR receptor-related disorder. Examples of such disorders are obesity and related disorders such as diabetes type II, dyslipidemia and the metabolic syndrome Prader-Willi syndrome, cardiovascular diseases such as atherosclerotic vascular disease, angina pectoris, myocardial infarction and stroke, acromegaly and cancer, in particular breast, lung, prostate, thyroid and endocrine pituary carcinomas.