2-[(2-Aminoacetyl)amino]-3-(4-fluorophenyl)propanoic acid

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2-[(2-Aminoacetyl)amino]-3-(4-fluorophenyl)propanoic acid
• 化学式: C₁₁H₁₃FN₂O₃
• 分子量: 240.234
• InChiKey: DQOXENRTKOLOJY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.8
• 重原子数：
  17
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  92.4
• 氢给体数：
  3
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  、 聚甘氨酸 生成 2-[(2-Aminoacetyl)amino]-3-(4-fluorophenyl)propanoic acid
  参考文献：
  名称：

  摘要：

  DOI：

文献信息

• Antimicrobial compounds and/or modulators of microbial infections and methods of using the same
  申请人：Indiana University Research and Technology Corporation

  公开号：US10793594B2

  公开（公告）日：2020-10-06

  Some embodiments include compounds that can inhibit the growth of bacterial and/or inhibit or reduce microbial infections caused by one or more microorganisms (e.g., Pseudomonas aeruginosa and Cryptococcus neoformans) and methods of using these compounds to treat microbial infection and outbreaks and/or to reduce the formation of biofilms. Other embodiments include synthesis of the compounds that can inhibit the growth of one or more microorganisms and/or inhibit or reduce microbial infections.

  一些实施方案包括可抑制细菌生长和/或抑制或减少由一种或多种微生物（如铜绿假单胞菌和新生隐球菌）引起的微生物感染的化合物，以及使用这些化合物治疗微生物感染和爆发和/或减少生物膜形成的方法。其它实施方案包括合成可抑制一种或多种微生物生长和/或抑制或减少微生物感染的化合物。
• ANTIMICROBIAL COMPOUNDS AND/OR MODULATORS OF MICROBIAL INFECTIONS AND METHODS OF USING THE SAME
  申请人：Indiana University Research and Technology Corporation

  公开号：US20210054025A1

  公开（公告）日：2021-02-25

  Some embodiments include compounds that can inhibit the growth of bacterial and/or inhibit or reduce microbial infections caused by one or more microorganisms (e.g., Pseudomonas aeruginosa and Cryptococcus neoformans ) and methods of using these compounds to treat microbial infection and outbreaks and/or to reduce the formation of biofilms. Other embodiments include synthesis of the compounds that can inhibit the growth of one or more microorganisms and/or inhibit or reduce microbial infections.