Bis(2-hydroxyethyl) Azelate | 29602-44-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: Bis(2-hydroxyethyl) Azelate
• 英文别名: Nonanedioic acid, bis(2-hydroxyethyl) ester；bis(2-hydroxyethyl) nonanedioate
• CAS: 29602-44-6
• 化学式: C₁₃H₂₄O₆
• 分子量: 276.33
• InChiKey: RLLLKKWXYJLXOU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  19
• 可旋转键数：
  14
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.85
• 拓扑面积：
  93.1
• 氢给体数：
  2
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  壬二酸 、 环氧乙烷 、 4-甲基-2-戊酮 在 catalyst 作用下， 以gave bis(2-hydroxy ethyl)azelate in quantitative crude的产率得到Bis(2-hydroxyethyl) Azelate
  参考文献：
  名称：

  Preparation of 2-hydroxyalkyl esters

  摘要：

  本专利描述了在高温、常温和低温下，催化促进含环氧化合物与羧酸化合物反应的方法。具体而言，本专利描述了在活性铬III三羧酸盐的存在下，将含环氧化合物与含羧基化合物反应的方法，最好在常温或附近温度下进行。更具体地说，本专利描述了如何从通常催化不活性的铬III三羧酸盐水合物中制备具有催化活性的铬III三羧酸盐。这些化合物是将环氧化合物与有机羧酸和环状一级亚胺反应的强力催化剂。

  公开号：

  US04017429A1

文献信息

• Chromium salt catalysts
  申请人：Aerojet-General Corporation

  公开号：US03968135A1

  公开（公告）日：1976-07-06

  This patent describes the catalytic promotion of the reaction of oxirane-containing compounds with carboxylic acid compounds at high, ambient, and low temperature. Specifically, this patent describes the method of reacting oxirane-containing compounds with carboxyl-containing compounds, preferably at temperatures at or around ambient, in the presence of active chromium III tricarboxylate salts which have unoccupied coordination sites. More specifically this patent describes the preparation of catalytically active chromium III-tricarboxylates from normally catalytically inactive chromium III tri-carboxylate hydrates. These compounds are powerful catalysts for the reactions of oxirane compounds with both organic carboxylic acids and cyclic primary imides.

  本专利描述了在高温、常温和低温下，催化促进含环氧化合物与羧酸化合物的反应。具体而言，本专利描述了在活性铬三羧酸盐的存在下，将含环氧化合物与含羧基化合物反应的方法，优选在常温或周围温度下进行。更具体而言，本专利描述了从通常具有催化不活性的铬三羧酸盐水合物中制备具有催化活性的铬三羧酸盐的方法。这些化合物是含环氧化合物与有机羧酸、环状初级酰胺反应的强力催化剂。
• Coating compositions comprising hydroxy ester, aminoplast and acrylic polyol oligomer and their use
  申请人：ROHM AND HAAS COMPANY

  公开号：EP0028898A2

  公开（公告）日：1981-05-20

  Coating compositions contain hydroxy esters, aminoplast and acrylic polyol oligomer. The esters may be formed by the reaction of C2-C12 diols or epoxy compounds with C2-C13 aliphatic dicarboxylic acids, or anhydrides or alkyl esters thereof. Bis-(ß-hydroxyalkyl) esters, such as bis-(ß- hydroxyethyl)adipate or azelate are preferred. N-methylol groups and/or N-methylol ether group-containing amino resins may be used as aminoplast and obtained by reaction of an aldehyde, such as formaldehyde, with a compound containing amino or amido groups, such as melamine or urea. Suitable oligomers have a weight average molecular weight of from 400 to 30,000 and a dispersity of from 1.1 to 10. These hydroxyl functional polymers may contain units of hydroxyalkyl acrylates and/or methacrylates.

  涂料组合物含有羟基酯、氨基塑料和丙烯酸多元醇低聚物。这些酯可由 C2-C12 二元醇或环氧化合物与 C2-C13 脂肪族二羧酸或其酸酐或烷基酯反应生成。双（ß-羟基烷基）酯，如双（ß-羟乙基）己二酸酯或壬二酸酯是首选。含 N-甲醇基团和/或 N-甲醇醚基团的氨基树脂可用作氨基塑料，由醛（如甲醛）与含氨基或胺基的化合物（如三聚氰胺或尿素）反应而得。合适的低聚物的平均分子量为 400 至 30000，分散度为 1.1 至 10。这些羟基官能团聚合物可能含有丙烯酸羟烷基酯和/或甲基丙烯酸羟烷基酯单元。
• COPOLYESTERS AND PROCESSES FOR PREPARING COPOLYESTERS SUITABLE FOR USE IN FOOD CONTACT APPLICATIONS
  申请人：Dupont Teijin Films U.S. Limited Partnership

  公开号：EP3956380A1

  公开（公告）日：2022-02-23
• Skin care compositions
  申请人：Whewell Christopher J.

  公开号：US20090110657A1

  公开（公告）日：2009-04-30

  Provided are compositions which are suitable for topical application to mammalian skin for cleansing and anti-microbial properties. In one embodiment, the compositions include an ester of polyalkylene glycol monoazelate monolaurate. It is postulated that bacteria on or in the skin may cleave the ester linkage of a compound according to the present disclosure that is applied to the skin, which causes liberation of the acid moiety from the ester, which acid moiety then inhibits or kills the bacterium. Compositions according to the present disclosure may comprise skin creams, soaps, shampoos and lotions, and are especially effective in treating acne and acne-like skin ebullitions.
• CHAIN EXTENDERS
  申请人：Gunatillake Pathiraja Arachchillage

  公开号：US20110287102A1

  公开（公告）日：2011-11-24

  The present invention relates to chain extenders, processes for their preparation and their use in the preparation of biocompatible biodegradable polyurethanes and polyurethane ureas for biomedical applications such as stents, scaffolds for tissue engineering. The chain extenders comprise a compound of formula.(I)