homolanthionine | 102044-65-5

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: homolanthionine
• 英文别名: 2,2'-diamino-4,4'-sulfanediyl-di-butyric acid；2,2'-Diamino-4,4'-sulfandiyl-di-buttersaeure；Bis-(3-amino-3-carboxy-propyl)-sulfid；2-Amino-4-(3-amino-3-carboxypropyl)sulfanylbutanoic acid
• CAS: 102044-65-5
• 化学式: C₈H₁₆N₂O₄S
• 分子量: 236.292
• InChiKey: MBEPFGPQVBIIES-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -5.6
• 重原子数：
  15
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  152
• 氢给体数：
  4
• 氢受体数：
  7

反应信息

• 作为产物：
  描述：

  3,6-bis-[2-(3-amino-3-carboxy-propylmercapto)-ethyl]-piperazine-2,5-dione 在 盐酸 作用下， 生成 homolanthionine
  参考文献：
  名称：

  Stekol, Journal of Biological Chemistry, 1948, vol. 173, p. 153,155

  摘要：

  DOI：

文献信息

• The Preparation of the Diastereoisomers of Cystathionine and Homolanthionine¹
  作者：Sidney Weiss、Jakob A. Stekol

  DOI：10.1021/ja01150a026

  日期：1951.6
• Prochazka, Zdenko; Smolikova, Jorga; Malon, Petr, Collection of Czechoslovak Chemical Communications, 1981, vol. 46, # 11, p. 2935 - 2946
  作者：Prochazka, Zdenko、Smolikova, Jorga、Malon, Petr、Jost, Karel

  DOI：——

  日期：——
• MONOTHIOETHER CROSSLINKERS IN POLYMERS AND APPLICATIONS THEREOF
  申请人：Zymergen Inc.

  公开号：US20210206802A1

  公开（公告）日：2021-07-08

  A polypeptide comprises amino acids in an amino acid sequence, wherein a portion of the amino acids are covalently linked via a monothioether bridge. In one embodiment, the portion includes amino acids selected from (I) herein n is 0, 1, or 2 and m is 1 or 2. In another embodiments, a hydrogel can include such an amino acid as a crosslinker.
• [EN] MONOTHIOETHER CROSSLINKERS IN POLYMERS AND APPLICATIONS THEREOF<br/>[FR] AGENTS DE RÉTICULATION DE MONOTHIOÉTHER DANS DES POLYMÈRES ET LEURS APPLICATIONS
  申请人：ZYMERGEN INC

  公开号：WO2020068185A2

  公开（公告）日：2020-04-02

  A polypeptide comprises amino acids in an amino acid sequence, wherein a portion of the amino acids are covalently linked via a monothioether bridge. In one embodiment, the portion includes amino acids selected from (I) herein n is 0, 1, or 2 and m is 1 or 2. In another embodiments, a hydrogel can include such an amino acid as a crosslinker.