hexadecyl glycerate | 130427-08-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: hexadecyl glycerate
• 英文别名: Hexadecanyl Glyceryl Ether；Hexadecyl 2,3-dihydroxypropanoate
• CAS: 130427-08-6
• 化学式: C₁₉H₃₈O₄
• 分子量: 330.508
• InChiKey: HDUBEBGNXHQZAR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.6
• 重原子数：
  23
• 可旋转键数：
  18
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.95
• 拓扑面积：
  66.8
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  hexadecyl glycerate 在 吡啶 作用下， 以 氯仿 为溶剂， 反应 16.0h， 生成 hexadecyl 2-acetyl-3-(triphenylmethyl)glycerate
  参考文献：
  名称：

  Analogues of phospholipids: synthesis and biological evaluation of a series of 3-phosphocholine glyceric acid derivatives

  摘要：

  DOI：

  10.1016/0223-5234(90)90116-k
• 作为产物：
  描述：

  碘十六烷 、 calcium glycerate 以 六甲基磷酰三胺 为溶剂， 反应 72.0h， 以96%的产率得到hexadecyl glycerate
  参考文献：
  名称：

  Analogues of phospholipids: synthesis and biological evaluation of a series of 3-phosphocholine glyceric acid derivatives

  摘要：

  DOI：

  10.1016/0223-5234(90)90116-k

文献信息

• Glycerin derivatives and process for producing the same
  申请人：KAO CORPORATION

  公开号：EP0624563A1

  公开（公告）日：1994-11-17

  Glycerine derivatives represented by formula (1A), (2A) and (3A): wherein R1a, R2a, R1b, R2b, R1c, and R2c are as defined in the disclosure, and process for producing glycerin derivatives, including the glycerin derivatives (1A), (2A) and (3A), are disclosed. The glycerin derivatives have satisfactory physical properties and are applicable as lubricants or polar oils and also have mutual effects with water and are applicable as emulsifying agents or moisture retaining agents. The process makes it possible to synthesize glycerin derivatives from easily and economically available aldehydes or ketones in high yields.

  公式（1A）、（2A）和（3A）代表的甘油衍生物：其中R1a、R2a、R1b、R2b、R1c和R2c如披露中所定义，并公开了生产甘油衍生物的方法，包括甘油衍生物（1A）、（2A）和（3A）。这些甘油衍生物具有令人满意的物理性质，可用作润滑剂或极性油，并且与水有相互作用，可用作乳化剂或保湿剂。该方法使得可以从易于获得且经济可行的醛类或酮类高产率地合成甘油衍生物。
• UV ABSORBER FORMULATIONS
  申请人：Acker Stephanie

  公开号：US20100111884A1

  公开（公告）日：2010-05-06

  Disclosed is a UV filter composition comprising (a) an organic UV absorber of formula (1), wherein R 1 and R 2 , independently of one another, are C 3 -C 18 alkyl; C 2 -C 18 alkenyl; a radical of the formula —CH 2 —CH(OH)—CH 2 —O-T 1 ; or R 1 and R 2 are a radical of the formula (4a); R 7 is a direct bond; a straight-chain or branched C 1 -C 4 alkylene radical or a radical of the formula (I) or (II); R 8 , R 9 and R 10 , independently of one another, are C 1 -C 18 alkyl; C 1 -C 18 alkoxy or a radical of the formula (III); R 11 is C 1 -C 5 alkyl; m 1 is a number from 1 to 4; p 1 is 0; or a number from 1 to 5; A 1 is a radical of the formula (1b), (1c) or (1d); R 3 is hydrogen; C 1 -C 10 alkyl; —(CH 2 CHR 5 —O)n 1 -T 2 ; or —CH 2 —CH(—OH)—CH 2 —O-T 2 ; R 4 is hydrogen; M; C 1 -C 5 alkyl; or —(CH 2 )m 2 —O-T 3 ; R 5 is hydrogen; or methyl; T 1 , T 2 and T 3 independently from each other are hydrogen; or C 1 -C 18 alkyl; Q 1 is C 1 -C 18 alkyl, M is a metal cation; m 2 is 1 to 4; and n 1 is 1-16, (b) dimethyl capramide, (c) a cosmetically acceptable carrier; and water.

  本发明公开了一种紫外线过滤组合物，包括（a）式（1）的有机紫外线吸收剂，其中R1和R2独立地是C3-C18烷基；C2-C18烯基；式—CH2—CH（OH）—CH2—O-T1的基团；或者R1和R2是式（4a）的基团；R7是直链或支链C1-C4烷基、式（I）或（II）的基团；R8、R9和R10独立地是C1-C18烷基、C1-C18烷氧基或式（III）的基团；R11是C1-C5烷基；m1是1至4的数字；p1是0或1至5的数字；A1是式（1b）、（1c）或（1d）的基团；R3是氢、C1-C10烷基、式—（CH2CHR5—O）n1-T2或式—CH2—CH（—OH）—CH2—O-T2；R4是氢、M、C1-C5烷基或式—（CH2）m2—O-T3；R5是氢或甲基；T1、T2和T3互相独立地是氢或C1-C18烷基；Q1是C1-C18烷基，M是金属阳离子；m2是1至4的数字；n1是1-16，（b）二甲基辛酰胺，（c）化妆品可接受载体；和水。
• ANIONIC LIPIDS AND LIPID NANO-STRUCTURES AND METHODS OF PRODUCING AND USING SAME
  申请人：Awasthi Vibhudutta

  公开号：US20110059157A1

  公开（公告）日：2011-03-10

  Anionic non-phospholipids, as well as lipid nanostructures formed therefrom, are disclosed herein. Also disclosed are methods of producing and using same.

  本文披露了阴离子非磷脂类物质以及由此形成的脂质纳米结构。同时还披露了其生产和使用方法。
• Alpha-mono(methyl-branched alkyl) glyceryl ether and a skin care cosmetic composition containing the same
  申请人：Kao Corporation

  公开号：EP0025302A1

  公开（公告）日：1981-03-18

  α-mono(methyl-branched alkyl) glyceryl ethers represented by the formula where m is an integer of 2 to 14, n is an integer of 3 to 11, and the total of m + n is 1 1 to 17, are disclosed along with skin care compositions containing the same as emulsifiers.

  α-单(甲基支链烷基)甘油醚由式 其中 m 为 2 至 14 的整数，n 为 3 至 11 的整数，m+n 的总和为 1 1 至 17。
• 2,3-Dialkoxypropyl glyceryl ether and its preparation process as well as cosmetic composition containing same
  申请人：KAO SOAP COMPANY, LTD.

  公开号：EP0071019A1

  公开（公告）日：1983-02-09

  Disclosed herein is a novel 2,3-dialkoxypropyl glyceryl ether and the preparation process for it. The above diglycerin dialkyl ether is readily prepared with high yield and purity by reacting its corresponding glycidyl ether with a protected glycerin to form a 1,3-dioxolan compound, followed by etherifying the thus formed 1,3-dioxolan compound into a dialkyl ether dioxolan compound, and then hydrolyzing the resultant dialkyl ether dioxolan compound. This diglycerin dialkyl ether is useful as an emulsifier, cleaner etc., and is preferably used as a component of cosmetic compositions. A cosmetic composition comprising the above 2,3- dialkoxypropyl glyceryl ether is also disclosed.

  本文公开了一种新型 2,3-二烷氧基丙基甘油醚及其制备工艺。上述二甘油二烷基醚很容易制备，产量和纯度都很高，制备方法是将相应的缩水甘油醚与受保护的甘油反应生成 1，3-二氧戊环化合物，然后将生成的 1，3-二氧戊环化合物醚化成二烷基醚二氧戊环化合物，再将生成的二烷基醚二氧戊环化合物水解。这种二甘油二烷基醚可用作乳化剂、清洁剂等，最好用作化妆品组合物的成分。此外，还公开了一种包含上述 2,3-二烷氧基丙基甘油醚的化妆品组合物。