4,4,5,5,6,6,6-heptafluoro-hexanoyl chloride | 1479-06-7

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 酰卤
• 英文名称: 4,4,5,5,6,6,6-heptafluoro-hexanoyl chloride
• 英文别名: 4,4,5,5,6,6,6-Heptafluor-hexanoylchlorid；4,4,5,5,6,6,6-Heptafluorohexanoyl chloride；4,4,5,5,6,6,6-heptafluorohexanoyl chloride
• CAS: 1479-06-7
• 化学式: C₆H₄ClF₇O
• 分子量: 260.539
• InChiKey: IIOAWLAIJMJORH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  15
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  8

反应信息

• 作为反应物：
  描述：

  4,4,5,5,6,6,6-heptafluoro-hexanoyl chloride 在 重氮甲烷 、 乙醚 作用下， 生成 5,5,6,6,7,7,7-heptafluoro-heptanoic acid amide
  参考文献：
  名称：

  Suicidal behavior—symptom or disorder?

  摘要：

  This article examines the diagnostic status of suicidal ideation with and without additional signs of defined or subthreshold mental disorders. Data from the World Health Organization (WHO) study on Psychological Problems in General Health Care (PPGHC) show that 8.8% of all general practice patients report that they recently had a wish to be dead. Among patients with acute depressive episodes, the rate is 34.5%, as compared with 1.3% in persons without any sign of mental disorder. Rates of suicidal ideation in persons with subthreshold disorders (10.4%) are similar to the rate in persons with other, nondepressed forms of mental disorders (12.9%). Still, 30.1% of all persons with suicidal ideation do not have a defined mental disorder, and 21.5% do not even have subthreshold disorders. But in these persons also, suicidal ideation is associated with an increased rate of depressive complaints. Suicidal ideation therefore, in any case, can be seen as an indicator of mental problems. But it seems impossible to lower the thresholds of defined mental disorders so that all forms of suicidal ideation will be covered. Instead, suicidal thoughts must be regarded as a symptom with the status of a disorder itself which should be handled as a comorbid condition if other mental disorders co-occur, Copyright (C) 2000 by W.B. Saunders Company.

  DOI：

  10.1016/s0010-440x(00)80017-6
• 作为产物：
  描述：

  4,4,5,5,6,6-六氟己酸 在 氯化亚砜 作用下， 生成 4,4,5,5,6,6,6-heptafluoro-hexanoyl chloride
  参考文献：
  名称：

  Suicidal behavior—symptom or disorder?

  摘要：

  This article examines the diagnostic status of suicidal ideation with and without additional signs of defined or subthreshold mental disorders. Data from the World Health Organization (WHO) study on Psychological Problems in General Health Care (PPGHC) show that 8.8% of all general practice patients report that they recently had a wish to be dead. Among patients with acute depressive episodes, the rate is 34.5%, as compared with 1.3% in persons without any sign of mental disorder. Rates of suicidal ideation in persons with subthreshold disorders (10.4%) are similar to the rate in persons with other, nondepressed forms of mental disorders (12.9%). Still, 30.1% of all persons with suicidal ideation do not have a defined mental disorder, and 21.5% do not even have subthreshold disorders. But in these persons also, suicidal ideation is associated with an increased rate of depressive complaints. Suicidal ideation therefore, in any case, can be seen as an indicator of mental problems. But it seems impossible to lower the thresholds of defined mental disorders so that all forms of suicidal ideation will be covered. Instead, suicidal thoughts must be regarded as a symptom with the status of a disorder itself which should be handled as a comorbid condition if other mental disorders co-occur, Copyright (C) 2000 by W.B. Saunders Company.

  DOI：

  10.1016/s0010-440x(00)80017-6

文献信息

• Partially fluorinated compositions and surface active agents
  申请人：Acosta Erick Jose

  公开号：US20080113172A1

  公开（公告）日：2008-05-15

  Partially fluorinated amino acid derivatives are provided that are useful as organogelators and surface treatment materials to provide oil- and water-repellency properties to substrates. Also provided are composite materials comprising a porous support and a porous nanoweb. The porous nanoweb contains fibrous structures of about 10 nm to about 1000 nm effective average fiber diameter.

  提供部分氟化氨基酸衍生物，可用作有机凝胶剂和表面处理材料，以赋予基材油和水的抗性。还提供了复合材料，包括多孔支撑体和多孔纳米网。多孔纳米网包含有效平均纤维直径约为10纳米至1000纳米的纤维结构。
• FLUOROALKYL SURFACTANTS
  申请人：E. I. du Pont de Nemours and Company

  公开号：EP2173703B1

  公开（公告）日：2011-11-30
• US7842626B2
  申请人：——

  公开号：US7842626B2

  公开（公告）日：2010-11-30
• Suicidal behavior—symptom or disorder?
  作者：B. Ahrens、M. Linden、H. Zäske、H. Berzewski

  DOI：10.1016/s0010-440x(00)80017-6

  日期：2000.3

  This article examines the diagnostic status of suicidal ideation with and without additional signs of defined or subthreshold mental disorders. Data from the World Health Organization (WHO) study on Psychological Problems in General Health Care (PPGHC) show that 8.8% of all general practice patients report that they recently had a wish to be dead. Among patients with acute depressive episodes, the rate is 34.5%, as compared with 1.3% in persons without any sign of mental disorder. Rates of suicidal ideation in persons with subthreshold disorders (10.4%) are similar to the rate in persons with other, nondepressed forms of mental disorders (12.9%). Still, 30.1% of all persons with suicidal ideation do not have a defined mental disorder, and 21.5% do not even have subthreshold disorders. But in these persons also, suicidal ideation is associated with an increased rate of depressive complaints. Suicidal ideation therefore, in any case, can be seen as an indicator of mental problems. But it seems impossible to lower the thresholds of defined mental disorders so that all forms of suicidal ideation will be covered. Instead, suicidal thoughts must be regarded as a symptom with the status of a disorder itself which should be handled as a comorbid condition if other mental disorders co-occur, Copyright (C) 2000 by W.B. Saunders Company.