1,8-Dioxa-cyclohexadecane-2,7-dione | 141850-49-9

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 大环内酯类和类似物
• 英文名称: 1,8-Dioxa-cyclohexadecane-2,7-dione
• 英文别名: Octamethylene adipate；1,8-dioxacyclohexadecane-2,7-dione
• CAS: 141850-49-9
• 化学式: C₁₄H₂₄O₄
• 分子量: 256.342
• InChiKey: NFXHFYVBOSKRMV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  18
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  Hexanedioic acid mono-(8-iodo-octyl) ester 在 silver tetrafluoroborate 、 caesium carbonate 作用下， 以 丙酮 为溶剂， 反应 84.0h， 生成 1,8-Dioxa-cyclohexadecane-2,7-dione
  参考文献：
  名称：

  Synthesis of macrocyclic dilactones by cyclization of sulfonium salts

  摘要：

  An efficient method for the formation of macrocyclic dilactones via cyclization of (omega-carboxyalkyl)diphenylsulfonium salts 3 containing an ester linkage under mild conditions is described. These sulfonium salts 3 were cyclized in the presence of cesium carbonate under high-dilution conditions to give 11- to 16-membered dilactones 4 in good yields. The cyclization of sulfonium salt 22 was successfully carried out for the synthesis of 11-membered dilactonic pyrrolizidine alkaloid, 13,13-dimethyl-1,2-didehydrocrotalanine 23.

  DOI：

  10.1021/jo00040a013

文献信息

• Enzyme-catalyzed polycondensations
  申请人：——

  公开号：US20040019178A1

  公开（公告）日：2004-01-29

  A method for enzymatic condensation polymerization by combining a preselected quantity of an enzyme, a diol and/or a polyol, and a diacid in a reaction vessel; heating the reaction vessel containing the enzyme, the diol or polyol, and the diacid to a preselected temperature; and maintaining the reaction vessel containing the enzyme, the diol and/or polyol, and the diacid at the preselected temperature for a preselected time, thereby producing a condensation polymer.

  一种酶促缩合聚合方法，将预先选择数量的酶、二元醇和/或多元醇以及二元酸放入反应容器中；将装有酶、二元醇或多元醇以及二元酸的反应容器加热到预先选择的温度；将装有酶、二元醇和/或多元醇以及二元酸的反应容器在预先选择的温度下保持预先选择的时间，从而生成缩合聚合物。
• US6846862B2
  申请人：——

  公开号：US6846862B2

  公开（公告）日：2005-01-25
• US6972315B2
  申请人：——

  公开号：US6972315B2

  公开（公告）日：2005-12-06
• [EN] BINDER SYSTEM AND METHOD FOR PARTICULATE MATERIAL<br/>[FR] PROCEDE ET SYSTEME DE LIANT POUR MATIERE PARTICULAIRE
  申请人：APEX ADVANCED TECHNOLOGIES LLC

  公开号：WO2002000569A2

  公开（公告）日：2002-01-03

  The present invention relates to a binder composition comprising an aliphatic polyester polymer; an ethylenebisamide wax; and a guanidine wetting agent. The composition may also contain an additive which accelerates or extends debinding of the binder composition, and to a method for forming a sintered part by powder injection molding, including the steps of forming a green composition comprising a binder and an inorganic powder, wherein the binder is a composition comprising an aliphatic polyester polymer, an ethylenebisamide wax, and a guanidine wetting agent, and may further include an additive which accelerates or delays completion of debinding of the binder; melting the composition; injecting the composition into a mold for a part; heating the part to a temperature at which the binder decomposes; heating the part to a temperature at which the inorganic powder is sintered.
• Synthesis of macrocyclic dilactones by cyclization of sulfonium salts
  作者：Takako Nakamura、Haruo Matsuyama、Nobumasa Kamigata、Masahiko Iyoda

  DOI：10.1021/jo00040a013

  日期：1992.7

  An efficient method for the formation of macrocyclic dilactones via cyclization of (omega-carboxyalkyl)diphenylsulfonium salts 3 containing an ester linkage under mild conditions is described. These sulfonium salts 3 were cyclized in the presence of cesium carbonate under high-dilution conditions to give 11- to 16-membered dilactones 4 in good yields. The cyclization of sulfonium salt 22 was successfully carried out for the synthesis of 11-membered dilactonic pyrrolizidine alkaloid, 13,13-dimethyl-1,2-didehydrocrotalanine 23.