N-(2,6-Diethyl-phenyl)-N-methyl-acetamide | 137090-10-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-(2,6-Diethyl-phenyl)-N-methyl-acetamide
• 英文别名: 2,6-diethyl-N-(methyl)acetanilide；N-(2,6-diethylphenyl)-N-methylacetamide
• CAS: 137090-10-9
• 化学式: C₁₃H₁₉NO
• 分子量: 205.3
• InChiKey: CLBWEJQLLASVFH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  15
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  20.3
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  2,6-二乙基-乙酰苯胺 、 硫酸二甲酯 在 sodium hydroxide 、 四丁基硫酸氢铵 、 potassium carbonate 作用下， 生成 N-(2,6-Diethyl-phenyl)-N-methyl-acetamide
  参考文献：
  名称：

  Facile Synthesis of Substituted N-Monoalkylaromatic Amines Under PTC Conditions

  摘要：

  Substituted aromatic amides were alkylated under PTC conditions. Compounds with ortho electron withdrawing substituents furnished exclusively monoalkyl amines. A plausible mechanism has been suggested.

  DOI：

  10.1080/00397919108021779

文献信息

• Immunoassay for the detection of alpha-haloacetamides
  申请人：Monsanto Company

  公开号：EP0340198A1

  公开（公告）日：1989-11-02

  Antigens, antibodies, antisera and diagnostic assay kits used in an enzyme-linked immunosorbent assay (ELISA) for α-haloacetamide herbicides.

  用于α-卤乙酰胺除草剂酶联免疫吸附试验（ELISA）的抗原、抗体、抗血清和诊断试剂盒。
• Facile Synthesis of Substituted N-Monoalkylaromatic Amines Under PTC Conditions
  作者：U. R. Kalkote、A. R. Choudhary、A. A. Natu、R. J. Lahoti、N. R. Ayyangar

  DOI：10.1080/00397919108021779

  日期：1991.9

  Substituted aromatic amides were alkylated under PTC conditions. Compounds with ortho electron withdrawing substituents furnished exclusively monoalkyl amines. A plausible mechanism has been suggested.