3-p-Chlorphenyl-6-phenylpyridazin | 2166-05-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: 3-p-Chlorphenyl-6-phenylpyridazin
• 英文别名: 6-(p-Chlorphenyl)-3-phenylpyridazine；3-Phenyl-6-(4-chlor-phenyl)-pyridazin；3-(4-chloro-phenyl)-6-phenyl-pyridazine；3-(4-Chlorophenyl)-6-phenylpyridazine
• CAS: 2166-05-4
• 化学式: C₁₆H₁₁ClN₂
• 分子量: 266.73
• InChiKey: SHERFVLHURBFCD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  19
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  25.8
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  7'-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-9,9'-spirobi[fluorene]-2'-carbonitrile 、 3-p-Chlorphenyl-6-phenylpyridazin 在 potassium phosphate 、 bis(dibenzylideneacetone)-palladium⁽⁰⁾ 、 三环己基膦 作用下， 以 1,4-二氧六环 、 水 为溶剂， 反应 5.0h， 生成
  参考文献：
  名称：

  신규한 화합물 및 이를 포함하는 유기발광 소자

  摘要：

  这项发明提供了一种新的化合物和包含它的有机发光器件。

  公开号：

  KR20210144979A
• 作为产物：
  描述：

  N-[[2-bromo-1-(4-chlorophenyl)ethylidene]amino]benzenesulfonamide 以 四氢呋喃 、 苯 为溶剂， 反应 6.0h， 生成 3-p-Chlorphenyl-6-phenylpyridazin
  参考文献：
  名称：

  Degradational Cyclization of a-[2-Phenyl-2-(phenylsulfonylhydrazono)ethyl]phenacylidenetriphenylphosphoranes to 3,6-Diphenylpyridazines and 5-Benzoyl-3-phenylpyrazoles

  摘要：

  alpha-[2-Phenyl-2-(phenylsulfonylhydrazono)ethyl]phenacylidene- triphenylphosphoranes were obtained (60-71%) by the reaction between phenylsulfonylhydrazones of phenacyl bromides and phenacylidenetriphenylphosphoranes. Thermolysis of the phosphoranes gave 3,6-diphenylpyridazines (43-66%) and 5-benzoyl-3-phenylpyrazoles (13-27%), together with triphenylphosphine oxide and S-phenyl benzenethiosulfonate, a disproportionation product from benzenesulfinic acid. The structure of the intermediate alpha-substituted phenacylidenetriphenylphosphorane was confirmed by an X-Ray diffraction method.

  DOI：

  10.3987/com-99-8733

文献信息

• Solid Phase Synthesis of Pyridazine Derivatives Using Polymer-Bound Sodium Benzenesulfinate
  作者：Yu Chen、Yulin Lam、Soo-Ying Lee

  DOI：10.1246/cl.2001.274

  日期：2001.3

  solid phase synthesis of 3,6-disubstituted pyridazine derivatives, resulting from the reaction of polymer-bound sodium benzenesulfinate with α-bromoketone substrates followed by condensation with hydrazine, is described. Mild basic conditions for the condensation reaction simultaneously release the desired product from the solid support. The crystal structure of 3,6-bis(p-chlorophenyl)pyridazine is reported

  描述了一种新的 3,6-二取代哒嗪衍生物的固相合成，该合成由聚合物结合的苯亚磺酸钠与 α-溴酮底物反应，然后与肼缩合而成。缩合反应的温和碱性条件同时从固体载体上释放出所需的产物。报道了 3,6-双（对氯苯基）哒嗪的晶体结构。
• Heterocyclic compound and organic light emitting device using the same
  申请人：LG CHEM, LTD.

  公开号：US11081655B2

  公开（公告）日：2021-08-03

  The present disclosure relates to a novel cyclic compound represented by Chemical Formula 1 and an organic light emitting device using the same. The compound is used as a material of an organic material layer of the organic light emitting device.

  本公开涉及一种由化学式 1 表示的新型环状化合物和使用该化合物的有机发光器件。该化合物用作有机发光器件有机材料层的材料。
• KADDAH A. M.; KHALIL A. M., INDIAN J. CHEM., 1977, B 15, NO 11, 1025-1028
  作者：KADDAH A. M.、 KHALIL A. M.

  DOI：——

  日期：——
• Degradational Cyclization of a-[2-Phenyl-2-(phenylsulfonylhydrazono)ethyl]phenacylidenetriphenylphosphoranes to 3,6-Diphenylpyridazines and 5-Benzoyl-3-phenylpyrazoles
  作者：Suketaka Ito、Akikazu Kakehi、Kyoko Okada

  DOI：10.3987/com-99-8733

  日期：——

  alpha-[2-Phenyl-2-(phenylsulfonylhydrazono)ethyl]phenacylidene- triphenylphosphoranes were obtained (60-71%) by the reaction between phenylsulfonylhydrazones of phenacyl bromides and phenacylidenetriphenylphosphoranes. Thermolysis of the phosphoranes gave 3,6-diphenylpyridazines (43-66%) and 5-benzoyl-3-phenylpyrazoles (13-27%), together with triphenylphosphine oxide and S-phenyl benzenethiosulfonate, a disproportionation product from benzenesulfinic acid. The structure of the intermediate alpha-substituted phenacylidenetriphenylphosphorane was confirmed by an X-Ray diffraction method.
• 신규한 화합물 및 이를 포함하는 유기발광 소자
  申请人：LG CHEM, LTD. 주식회사 엘지화학(120010134563) Corp. No ▼ 110111-2207995BRN ▼107-81-98139

  公开号：KR20210144979A

  公开（公告）日：2021-12-01

  본 발명은 신규한 화합물 및 이를 포함하는 유기 발광 소자를 제공한다.

  这项发明提供了一种新的化合物和包含它的有机发光器件。