[4,5-Bis[3,4-bis[[tert-butyl(dimethyl)silyl]oxy]phenyl]-2-[tert-butyl(dimethyl)silyl]oxyphenoxy]-tert-butyl-dimethylsilane | 1206881-88-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: [4,5-Bis[3,4-bis[[tert-butyl(dimethyl)silyl]oxy]phenyl]-2-[tert-butyl(dimethyl)silyl]oxyphenoxy]-tert-butyl-dimethylsilane
• 英文别名: [4,5-bis[3,4-bis[[tert-butyl(dimethyl)silyl]oxy]phenyl]-2-[tert-butyl(dimethyl)silyl]oxyphenoxy]-tert-butyl-dimethylsilane
• CAS: 1206881-88-0
• 化学式: C₅₄H₉₈O₆Si₆
• 分子量: 1011.88
• InChiKey: BFOYWJDGYRGMSH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  19.32
• 重原子数：
  66
• 可旋转键数：
  20
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  55.4
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  [4,5-Bis[3,4-bis[[tert-butyl(dimethyl)silyl]oxy]phenyl]-2-[tert-butyl(dimethyl)silyl]oxyphenoxy]-tert-butyl-dimethylsilane 在 四丁基氟化铵 作用下， 以 四氢呋喃 为溶剂， 反应 2.0h， 以93%的产率得到2,3,6,7,10,11-六羟基三苯
  参考文献：
  名称：

  Facile Cyclization of Terphenyl to Triphenylene: A New Chemodosimeter for Fluoride Ions

  摘要：

  Terphenyl derivatives 3 and 4 having OTBS groups have been synthesized via a Suzuki-Miyura coupling reaction, These compounds undergo unprecedented irreversible cyclization to symmetrically/unsymmetrically substituted triphenylenes while carrying out the deprotection of OTBS groups using tetrabutylammonium fluoride. Terphenyl 3 also serves as a new chemodosimeter for fluoride ions.

  DOI：

  10.1021/ol902861b
• 作为产物：
  描述：

  1,2-dibromo-4,5-bis(tert-butyldimethylsilyloxy)benzene 、 (4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2-phenylene)bis(oxy)bis(tert-butyldimethylsilane) 在 四(三苯基膦)钯 、 potassium carbonate 作用下， 以 乙醇 、 水 、 甲苯 为溶剂， 以86%的产率得到[4,5-Bis[3,4-bis[[tert-butyl(dimethyl)silyl]oxy]phenyl]-2-[tert-butyl(dimethyl)silyl]oxyphenoxy]-tert-butyl-dimethylsilane
  参考文献：
  名称：

  Facile Cyclization of Terphenyl to Triphenylene: A New Chemodosimeter for Fluoride Ions

  摘要：

  Terphenyl derivatives 3 and 4 having OTBS groups have been synthesized via a Suzuki-Miyura coupling reaction, These compounds undergo unprecedented irreversible cyclization to symmetrically/unsymmetrically substituted triphenylenes while carrying out the deprotection of OTBS groups using tetrabutylammonium fluoride. Terphenyl 3 also serves as a new chemodosimeter for fluoride ions.

  DOI：

  10.1021/ol902861b