N-{2-[2-(2-Amino-ethoxy)-ethoxy]-ethyl}-3-mercapto-propionamide | 474903-32-7

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: N-{2-[2-(2-Amino-ethoxy)-ethoxy]-ethyl}-3-mercapto-propionamide
• CAS: 474903-32-7
• 化学式: C₉H₂₀N₂O₃S
• 分子量: 236.335
• InChiKey: ZMCBIVJKUWPPKC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.59
• 重原子数：
  15.0
• 可旋转键数：
  10.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  73.58
• 氢给体数：
  3.0
• 氢受体数：
  5.0

反应信息

• 作为反应物：
  描述：

  N-{2-[2-(2-Amino-ethoxy)-ethoxy]-ethyl}-3-mercapto-propionamide 以 乙醇 、 水 为溶剂， 反应 18.0h， 生成 3-[3-(2-{2-[2-(2-ethoxy-3,4-dioxocyclobut-1-en-1-ylamino)ethoxy]ethoxy}ethylamino)oxopropylthio]propyl 2-O-(2-acetamido-3,4,6-tri-O-benzyl-2-deoxy-β-D-glucopyranosyl)-3-O-carbamoyl-α-D-galactopyranosiduronamide
  参考文献：
  名称：

  Synthesis of tools for raising antibodies against moenomycin epitopes and initial immunological studies

  摘要：

  The moenomycins A and C-1 as well as penta-. di- and monosaccharide analogues have been conjugated to BSA and biotin, respectively, The moenomycin A-BSA conjugates have been used to raise polyclonal antibodies. It has been demonstrated that the antisera recognize moenomycin A. (C) 2002 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4020(02)00838-4
• 作为产物：
  描述：

  2-(2-(2-氨基乙氧基)乙氧基)乙基氨基甲酸叔丁酯 生成 N-{2-[2-(2-Amino-ethoxy)-ethoxy]-ethyl}-3-mercapto-propionamide
  参考文献：
  名称：

  Synthesis of tools for raising antibodies against moenomycin epitopes and initial immunological studies

  摘要：

  The moenomycins A and C-1 as well as penta-. di- and monosaccharide analogues have been conjugated to BSA and biotin, respectively, The moenomycin A-BSA conjugates have been used to raise polyclonal antibodies. It has been demonstrated that the antisera recognize moenomycin A. (C) 2002 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4020(02)00838-4