Malonic acid bis-(9H-fluoren-9-ylmethyl) ester | 488841-18-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 芴
• 英文名称: Malonic acid bis-(9H-fluoren-9-ylmethyl) ester
• 英文别名: bis(9H-fluoren-9-ylmethyl) propanedioate
• CAS: 488841-18-5
• 化学式: C₃₁H₂₄O₄
• 分子量: 460.529
• InChiKey: INFLLUCSTGWJDL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.4
• 重原子数：
  35
• 可旋转键数：
  8
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.16
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  Malonic acid bis-(9H-fluoren-9-ylmethyl) ester 在 caesium carbonate 、 pyridinium hydrobromide perbromide 作用下， 以 氯仿 、 N,N-二甲基甲酰胺 为溶剂， 生成 Benzo[1,3]dioxole-2,2-dicarboxylic acid bis-(9H-fluoren-9-ylmethyl) ester
  参考文献：
  名称：

  Synthesis of a New Fluorescent Probe Specific for Catechols

  摘要：

  [GRAPHICS]The synthesis of a new fluorescent probe, specific for the catechol moiety, has been conducted by preparation of alpha,alpha-dibromomalonamides containing an appropriate fluorophore. N,N'-Bis-anthracen-9-ylmethyl-2,2-dibromomalonamide reacted with various catechols in the presence of cesium carbonate to generate highly fluorescent derivatives.

  DOI：

  10.1021/ol027000j
• 作为产物：
  描述：

  丙二酸 、 9-芴甲醇 在 10percent TsOH 作用下， 以 甲苯 为溶剂， 生成 Malonic acid bis-(9H-fluoren-9-ylmethyl) ester
  参考文献：
  名称：

  Synthesis of a New Fluorescent Probe Specific for Catechols

  摘要：

  [GRAPHICS]The synthesis of a new fluorescent probe, specific for the catechol moiety, has been conducted by preparation of alpha,alpha-dibromomalonamides containing an appropriate fluorophore. N,N'-Bis-anthracen-9-ylmethyl-2,2-dibromomalonamide reacted with various catechols in the presence of cesium carbonate to generate highly fluorescent derivatives.

  DOI：

  10.1021/ol027000j

文献信息

• Synthesis of a New Fluorescent Probe Specific for Catechols
  作者：Douglas E. Stack、Anastacia L. Hill、Clark B. Diffendaffer、Nicole M. Burns

  DOI：10.1021/ol027000j

  日期：2002.12.1

  [GRAPHICS]The synthesis of a new fluorescent probe, specific for the catechol moiety, has been conducted by preparation of alpha,alpha-dibromomalonamides containing an appropriate fluorophore. N,N'-Bis-anthracen-9-ylmethyl-2,2-dibromomalonamide reacted with various catechols in the presence of cesium carbonate to generate highly fluorescent derivatives.