[PtCl(pyrrolidinedithiocarbamate)(dimethyl sulfoxide)] | 1338964-03-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯烷类
• 英文名称: [PtCl(pyrrolidinedithiocarbamate)(dimethyl sulfoxide)]
• 英文别名: [PtCl(PyDT)(DMSO)]
• CAS: 1338964-03-6
• 化学式: C₂H₆OS*C₅H₈NS₂*Cl*Pt
• 分子量: 454.925
• InChiKey: QTLQUGWSENIMCR-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  -2.09
• 重原子数：
  14.0
• 可旋转键数：
  0.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  20.31
• 氢给体数：
  0.0
• 氢受体数：
  3.0

反应信息

• 作为产物：
  描述：

  [PtCl(pyrrolidinedithiocarbamate)]5 、 二甲基亚砜 以 not given 为溶剂， 生成 [PtCl(pyrrolidinedithiocarbamate)(dimethyl sulfoxide)]
  参考文献：
  名称：

  Unique Pt5 metallacycle: [PtIICl(pyrrolidinedithiocarbamate)]5

  摘要：

  中性配合物 [PtCl(PyDT)]5 (PyDT = (CH2)4NCS2−) 代表 Pt5 金属环的第一个例子。这种基于手性 S 桥接 PtII 单体的独特结构是通过 PtCl2 和吡咯烷二硫酯的反应产物热降解制备的。

  DOI：

  10.1039/c1dt11475a

文献信息

• Synthesis, crystal structure and antimicrobial studies of chlorido(dimethylsulfoxide-κS)(pyrrolidinedithiocarbamato-κ2S,S/)platinum(II)
  作者：Anvarhusein A. Isab、Muhammad Akhtar Javed Ali、Shahzad Sharif、Islam Ullah Khan、Sung Kwon Kang、Tanzeel Khalid、Muhammad Saleem、Saeed Ahmad

  DOI：10.1016/j.inoche.2011.09.021

  日期：2011.12

  Platinum(II) complexes, [Pt(PDTC)(H2O)Cl] and [Pt(PDTC)(DMSO)Cl] (1) (PDTC = pyrrolidinedithiocarbamate) have been prepared and characterized by IR, NMR and X-ray crystallographic methods. In the crystal structure of 1 the central platinum atom is coordinated to two sulfur atoms of PDTC, one sulfur atom of DMSO and one chloride ion adopting a square planar geometry with the average cis and trans bond angles of 90.00 degrees and 171.62 degrees respectively. The H-1 and C-13 NMR spectral data indicate the coordination of both PDTC and DMSO to platinum(II). The title complex was screened for antimicrobial effects and the results show that it exhibits significant activity against gram-negative bacteria (E. coli, P. aeruginosa), while the activities are moderate against molds (A. niger, P. citrinum) and yeasts (C. albicans, S. serevisaiae). (C) 2011 Elsevier B.V. All rights reserved.