1-bromomethyl-2-chloro-naphthalene | 858024-92-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 1-bromomethyl-2-chloro-naphthalene
• 英文别名: 1-Brommethyl-2-chlor-naphthalin；1-(Bromomethyl)-2-chloronaphthalene
• CAS: 858024-92-7
• 化学式: C₁₁H₈BrCl
• 分子量: 255.542
• InChiKey: XDCYZEUAFWXRHF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  13
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.09
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  1-bromomethyl-2-chloro-naphthalene 在 potassium cyanide 、 sodium hydroxide 、 丙酮 作用下， 生成 (2-chloro-[1]naphthyl)-acetic acid
  参考文献：
  名称：

  Joensson, Svensk Kemisk Tidskrift, 1955, vol. 67, p. 162,163

  摘要：

  DOI：
• 作为产物：
  描述：

  2-羟基-1-萘甲醛 在 氢氧化钾 、 乙醇 、 五氯化磷 、 氢溴酸 、 苯 作用下， 生成 1-bromomethyl-2-chloro-naphthalene
  参考文献：
  名称：

  Hypnotic Intervention for Ambiguity as a Depressive Risk Factor

  摘要：

  In the face of ambiguous life events, depressed individuals are more likely to make negative and depressing interpretations than nondepressed individuals. Fundamental to the success of cognitive-behavioral treatments, one of the most empirically supported treatments for depression is teaching the client to recognize and self-correct so-called cognitive distortions. To facilitate that learning process, clients can learn to better recognize and tolerate ambiguity inherent in many situations, and thereby diminish the drive to form subjective interpretations (either negative or positive) when more objective evidence is unavailable. This article describes ambiguity as a risk factor for depression and details a strategy employing hypnosis for teaching the skills of both recognizing and tolerating ambiguity.

  DOI：

  10.1080/00029157.2001.10403466