1,3,5-tris(4-methoxy-5-formylphenyl)benzene | 1222784-87-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1,3,5-tris(4-methoxy-5-formylphenyl)benzene
• 英文别名: 5-[3,5-Bis(3-formyl-4-methoxyphenyl)phenyl]-2-methoxybenzaldehyde
• CAS: 1222784-87-3
• 化学式: C₃₀H₂₄O₆
• 分子量: 480.517
• InChiKey: CDLFEUWMQOPZIS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.1
• 重原子数：
  36
• 可旋转键数：
  9
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  78.9
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  1,3,5-tris(4-methoxy-5-formylphenyl)benzene 在 三溴化硼 、 水 作用下， 以 二氯甲烷 为溶剂， 以66%的产率得到1,3,5-tris(4’-hydroxy-5’-formylphenyl)benzene
  参考文献：
  名称：

  Synthesis of Tri- and Disalicylaldehydes and Their Chiral Schiff Base Compounds

  摘要：

  A suitable procedure for convenient preparation of 1,3,5-tris(4-hydroxy-5-formylphenyl)benzene (6) was exploited via 5-bromosalicylaldehyde as starting reactant. Among the obtained products, compound 6, 4-methoxy-3-formylphenylboronic acid (9), 1,3,5-tris(4-methoxy-5-formylphenyl)benzene (10), and 4-methoxy-4'-hydroxyl-3,3'-diformyl-1,1'-diphenyl (11) had not been reported previously. Two new chiral Schiff base ligands, L1 and L2, were obtained from the tri- or disalicylaldehydes.

  DOI：

  10.1080/00397910903040252
• 作为产物：
  描述：

  1,3,5-三溴苯 、 3-甲酰基-4-甲氧基苯硼酸 在 四(三苯基膦)钯 、 potassium carbonate 作用下， 以 四氢呋喃 为溶剂， 反应 48.0h， 以51%的产率得到1,3,5-tris(4-methoxy-5-formylphenyl)benzene
  参考文献：
  名称：

  Synthesis and catalytic activity of heterogeneous rare-earth metal catalysts coordinated with multitopic Schiff-base ligands

  摘要：

  合成了四种多位点 Schiff 碱配体前体，通过 4,4′-二醇-3,3′-二福尔马基-1,1′-二苯基或 1,3,5-三(4-羟基-5-福尔马基苯基)苯与 2,6-二异丙基苯胺或 2,6-二甲基苯胺缩合反应得到。Ln[N(SiMe3)2]3 (Ln = La, Nd, Sm 或 Y) 与这些多位点配体前体的胺消除反应生成了十种异质稀土金属催化剂。这些异质稀土金属催化剂在烯醇的分子内氢醇化反应中具有活性，催化活性受到配体和金属离子的影响。对最活跃的异质催化剂进行的循环实验表明，该催化剂具有良好的可重复使用性。

  DOI：

  10.1039/c2dt30763d

文献信息

• Synthesis of Tri- and Disalicylaldehydes and Their Chiral Schiff Base Compounds
  作者：Hai-Bin Liu、Mei Wang、Ying Wang、Lin Wang、Li-Cheng Sun

  DOI：10.1080/00397910903040252

  日期：2010.3.12

  A suitable procedure for convenient preparation of 1,3,5-tris(4-hydroxy-5-formylphenyl)benzene (6) was exploited via 5-bromosalicylaldehyde as starting reactant. Among the obtained products, compound 6, 4-methoxy-3-formylphenylboronic acid (9), 1,3,5-tris(4-methoxy-5-formylphenyl)benzene (10), and 4-methoxy-4'-hydroxyl-3,3'-diformyl-1,1'-diphenyl (11) had not been reported previously. Two new chiral Schiff base ligands, L1 and L2, were obtained from the tri- or disalicylaldehydes.
• Synthesis and catalytic activity of heterogeneous rare-earth metal catalysts coordinated with multitopic Schiff-base ligands
  作者：Yilin Sun、Guangming Wu、Dinghai Cen、Yaofeng Chen、Limin Wang

  DOI：10.1039/c2dt30763d

  日期：——

  Four multitopic Schiff-base ligand precursors were synthesized via condensation of 4,4′-diol-3,3′-diformyl-1,1′-diphenyl or 1,3,5-tris(4-hydroxy-5-formylphenyl)benzene with 2,6-diisopropylaniline or 2,6-dimethylaniline. Amine elimination reactions of Ln[N(SiMe3)2]3 (Ln = La, Nd, Sm or Y) with these multitopic ligand precursors gave ten heterogeneous rare-earth metal catalysts. These heterogeneous rare-earth metal catalysts are active for intramolecular hydroalkoxylation of alkynols, and the catalytic activities are influenced by the ligand and metal ion. The recycling experiment on the most active heterogeneous catalyst showed the catalyst has a good reusability.

  合成了四种多位点 Schiff 碱配体前体，通过 4,4′-二醇-3,3′-二福尔马基-1,1′-二苯基或 1,3,5-三(4-羟基-5-福尔马基苯基)苯与 2,6-二异丙基苯胺或 2,6-二甲基苯胺缩合反应得到。Ln[N(SiMe3)2]3 (Ln = La, Nd, Sm 或 Y) 与这些多位点配体前体的胺消除反应生成了十种异质稀土金属催化剂。这些异质稀土金属催化剂在烯醇的分子内氢醇化反应中具有活性，催化活性受到配体和金属离子的影响。对最活跃的异质催化剂进行的循环实验表明，该催化剂具有良好的可重复使用性。