4-(二苄基氨基)丁酸 | 106518-44-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 4-(二苄基氨基)丁酸
• 英文名称: N,N-dibenzyl-γ-amino-n.butyric acid
• 英文别名: 4-(N,N-dibenzylamino)butyric acid；4-Dibenzylamino-buttersaeure；γ-(N,N-Dibenzylamino)-buttersaeure；4-dibenzylamino-butyric acid；4-dibenzylaminobutanoic acid；4-(Dibenzylazaniumyl)butanoate
• CAS: 106518-44-9
• 化学式: C₁₈H₂₁NO₂
• 分子量: 283.37
• InChiKey: RHPOFVFYZREVEF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  21
• 可旋转键数：
  8
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.28
• 拓扑面积：
  40.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  4-(二苄基氨基)丁酸 在 二苯基膦叠氮化物 、 三乙胺 作用下， 以 甲苯 为溶剂， 反应 72.0h， 生成 3-(N,N-dibenzylamino)propyl isocyanate
  参考文献：
  名称：

  Rapid Evaluation of Suitable Substrates with High Affinity to Artificial Caffeine Receptors by MS Based Techniques

  摘要：

  我们基于三苯基酮基受体的改型有助于电喷雾串联质谱研究。在气相中，通过碰撞诱导解离探测了十一个潜在底物（如咖啡因和其他黄嘌呤生物碱）的结合亲和力。底物-受体复合物的相对稳定性被迅速确定，并与溶液中的相应结果进行了相关性分析。

  DOI：

  10.1515/znb-2005-1010
• 作为产物：
  描述：

  methyl 4-(dibenzylamino)butanoate 在 盐酸 作用下， 生成 4-(二苄基氨基)丁酸
  参考文献：
  名称：

  Intramolecular Assistance of Decarboxylative Acylation

  摘要：

  DOI：

  10.1021/ja01474a024

文献信息

• Use of a compound having a monogalactosyldiacylglycerol synthase inhibitory activity as herbicide or algaecide, herbicide and algaecide compositions
  申请人：Commissariat à l'Energie Atomique

  公开号：EP1997381A1

  公开（公告）日：2008-12-03

  The invention relates to the use of compounds having a monogalactosyldiacylglycerol (MGDG) synthase inhibitory activity as herbicide or algaecide, and to herbicide and algaecide compositions containing at least one of these compounds.

  该发明涉及将具有单半乳糖二酰基甘油（MGDG）合成酶抑制活性的化合物用作除草剂或藻类杀灭剂，并且涉及含有至少一种这些化合物的除草剂和藻类杀灭剂组合物。
• Compounds with antiparasitic activity, applications thereof to the treatment of infectious diseases caused by apicomplexans
  申请人：Commissariat à l'Energie Atomique

  公开号：EP1997805A1

  公开（公告）日：2008-12-03

  The Invention relates to compounds having an antiparasitic activity, and to their use as a drug, in particular as a drug for the prevention and/or treatment of parasitic diseases caused by apicomplexans. The invention also relates to pharmaceutical compositions containing those compounds.

  这项发明涉及具有抗寄生虫活性的化合物，以及它们作为药物的用途，特别是作为预防和/或治疗由顶复合体寄生虫引起的寄生虫病的药物。该发明还涉及含有这些化合物的药物组合物。
• Use of Compounds Having a Mongalactosydiacylglycerol Syhnthase Inhibitory Activity as Herbicide or Algaecide, Herbicide and Algaecide Compositions
  申请人：Bonneau Anne-Laure

  公开号：US20100273653A1

  公开（公告）日：2010-10-28

  The invention relates to the use of compounds having a monogalactosyldiacylglycerol (MGDG) synthase inhibitory activity as herbicide or algaecide, and to herbicide and algaecide compositions containing at least one of these compounds.

  本发明涉及使用具有单半乳糖二酰基甘油（MGDG）合成酶抑制活性的化合物作为除草剂或藻类杀灭剂，以及含有至少一种这些化合物的除草剂和藻类杀灭剂组合物。
• Compounds having a monogalactosyldiacylglycerol synthase inhibitory activity as herbicide or algaecide, herbicide and algaecide compositions
  申请人：Bonneau Anne-Laure

  公开号：US08637496B2

  公开（公告）日：2014-01-28

  The invention relates to the use of compounds having a monogalactosyldiacylglycerol (MGDG) synthase inhibitory activity as herbicide or algaecide, and to herbicide and algaecide compositions containing at least one of these compounds.

  本发明涉及使用具有单半乳糖二酰基甘油（MGDG）合成酶抑制活性的化合物作为除草剂或杀藻剂，并涉及至少含有这些化合物之一的除草剂和杀藻剂组合物。
• Compounds with Antiparasitic Activity, Applications thereof to the Treatment of Infectious Diseases Caused by Apicomplexans
  申请人：Deligny Michael

  公开号：US20100292214A1

  公开（公告）日：2010-11-18

  The Invention relates to compounds having an antiparasitic activity, and to their use as a drug, in particular as a drug for the prevention and/or treatment of parasitic diseases caused by apicomplexans. The invention also relates to pharmaceutical compositions containing those compounds.

  本发明涉及具有抗寄生活性的化合物及其作为药物的使用，特别是用于预防和/或治疗由顶复门寄生虫引起的寄生虫病。本发明还涉及含有这些化合物的制药组合物。