Glycerin-tris-trifluoracetat | 26158-83-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 甘油脂
• 英文名称: Glycerin-tris-trifluoracetat
• 英文别名: Glycerintri-trifluoracetat；Glycerol-tri(trifluoroacetat)；trifluoroacetic acid 1,2,3-propanetriyl ester；Acetic acid, trifluoro-, 1,2,3-propanetriyl ester；2,3-bis[(2,2,2-trifluoroacetyl)oxy]propyl 2,2,2-trifluoroacetate
• CAS: 26158-83-8
• 化学式: C₉H₅F₉O₆
• 分子量: 380.121
• InChiKey: HPSVLRPPSOCJKG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  24
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  78.9
• 氢给体数：
  0
• 氢受体数：
  15

反应信息

• 作为产物：
  描述：

  甘油 、 三氟乙酸酐 生成 Glycerin-tris-trifluoracetat
  参考文献：
  名称：

  919F-NMR untersuchungen an trifluoracetylierten polyolen

  摘要：

  DOI：

  10.1016/s0040-4039(01)88513-0

文献信息

• N-Heterocyclic Carbene Palladium Catalyzed Regioselective Oxidative Trifluoroacetoxylation of Unactivated Methylene sp³C–H Bonds in Linear Alkyl Esters
  作者：Xiu-Feng Hou、Ya-Nong Wang、Inigo Göttker-Schnetmann

  DOI：10.1021/om200484g

  日期：2011.11.14

  Several N-heterocyclic carbene palladium catalyzed oxidation of nonactivated sp3 C–H bonds in linear primary and secondary trifluoroacetic acid esters have been developed. A high selectivity for the oxidation of the omega-1 carbon atom in trifluoroacetic acid n-propyl to n-octyl esters was realized by an appropriate choice of N-heterocyclic carbene palladium complexes.

  已经开发了几种N-杂环卡宾钯催化的线性伯和仲三氟乙酸酯中未活化的sp 3 C-H键的氧化。对于ω-1个碳原子的三氟乙酸氧化的高选择性Ñ丙基到Ñ辛基酯是由N-杂环卡宾钯络合物的适当选择来实现。
• Direct oxidation of olefins to oxygenated species
  申请人：The Scripps Research Institute

  公开号：US10858301B2

  公开（公告）日：2020-12-08

  Provided is a process for oxidizing an alkene. The process comprises contacting an alkene, and either an oxidizing electrophile comprising a main group element in oxidized form or an oxidant and a reduced form of the oxidizing electrophile, in a liquid medium comprising an oxygen acid and optionally one or more additives selected from a non-oxidizable liquid, a salt additive, a Lewis acid, and water, to provide an oxygenate and a reduced form of the oxidizing electrophile. The process optionally further comprises separating the oxygenate and the reduced form of the oxidizing electrophile. The oxygenate can be further hydrolyzed to form an alcohol, diol, or polyol.

  本发明提供了一种氧化烯烃的工艺。该工艺包括将烯和由氧化形式的主族元素组成的氧化亲电子体或氧化剂和氧化亲电子体的还原形式在由氧酸和可选的一种或多种选自非氧化液体、盐添加剂、路易斯酸和水的添加剂组成的液体介质中接触，以提供氧酸盐和氧化亲电子体的还原形式。该工艺可选地进一步包括分离氧化亲电子体的含氧酸盐和还原形式。含氧酸盐可进一步水解形成醇、二元醇或多元醇。
• Oxidation of alkane to alkene
  申请人：The Scripps Research Institute

  公开号：US11078136B2

  公开（公告）日：2021-08-03

  Provided is a process for converting an alkane to an alkene. The process comprises (a) contacting the alkane and either (i) an oxidizing electrophile comprising a main group element in oxidized form, or (ii) an oxidant and a reduced form of the oxidizing electrophile, in a liquid medium comprising an oxygen acid and optionally one or more additives selected from a non-oxidizable liquid, a salt additive, a Lewis acid, and water, to provide an oxidized intermediate and a reduced form of the oxidizing electrophile; (b) optionally separating the oxidized intermediate and the reduced form of the oxidizing electrophile; and (c) performing an elimination reaction on the oxidized intermediate to provide the alkene and the oxygen acid.

  本发明提供了一种将烷烃转化为烯的工艺。该工艺包括：(a) 将烷烃和(i) 由氧化形式的主族元素组成的氧化亲电子体，或(ii) 氧化剂和还原形式的氧化亲电子体，在包括氧酸和任选选自非氧化性液体、盐添加剂、路易斯酸和水的一种或多种添加剂的液体介质中接触，以提供氧化中间体和还原形式的氧化亲电子体；(b) 有选择地分离氧化中间体和还原形式的氧化亲电子体；以及 (c) 对氧化中间体进行消除反应，以提供烯和氧酸。
• Direct oxidative amination of hydrocarbons
  申请人：University of Florida Research Foundation, Incorporated

  公开号：US11396492B2

  公开（公告）日：2022-07-26

  Provided is a process for converting a hydrocarbon comprising at least one C—H bond to a nitrogen-functionalized product. The process comprises contacting a hydrocarbon and (i) an oxidizing electrophile comprising (a) a main group element or transition metal in oxidized form and (b) at least one nitrogen-containing ligand, or (ii) an oxidant and a reduced form of an oxidizing electrophile comprising (a) a main group element or transition metal and (b) at least one nitrogen-containing ligand, in a solvent to provide the nitrogen-functionalized product and an electrophile reduction product. Further provided is an oxidizing composition comprising the oxidizing electrophile with at least one nitrogen-containing ligand and a non-oxidizable liquid.

  提供了一种将包含至少一个 C-H 键的碳氢化合物转化为氮官能化产物的工艺。该工艺包括将碳氢化合物和(i)氧化亲电子体（包括(a)氧化形式的主族元素或过渡金属和(b)至少一种含氮配体），或(ii)氧化剂和还原形式的氧化亲电子体（包括(a)主族元素或过渡金属和(b)至少一种含氮配体）在溶剂中接触，以提供氮官能化产物和亲电子体还原产物。此外，还提供了一种氧化组合物，该组合物包含氧化亲电子体与至少一种含氮配体和一种不可氧化的液体。
• OXIDATION OF ALKANE TO ALKENE
  申请人：The Scripps Research Institute

  公开号：EP3634925A1

  公开（公告）日：2020-04-15