10-methoxyazuleno[2,1-c]phenanthrene | 1428551-98-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 菲及其衍生物
• 英文名称: 10-methoxyazuleno[2,1-c]phenanthrene
• 英文别名: 17-Methoxypentacyclo[12.8.0.02,11.03,8.016,22]docosa-1(14),2(11),3,5,7,9,12,15,17,19,21-undecaene；17-methoxypentacyclo[12.8.0.02,11.03,8.016,22]docosa-1(14),2(11),3,5,7,9,12,15,17,19,21-undecaene
• CAS: 1428551-98-7
• 化学式: C₂₃H₁₆O
• 分子量: 308.379
• InChiKey: YRKJMZMSVSKTIQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.6
• 重原子数：
  24
• 可旋转键数：
  1
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.04
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  3-乙炔基-4-(2-甲氧基苯基)菲 在 乙腈 、 platinum(II) chloride 作用下， 以 甲苯 为溶剂， 反应 7.0h， 以66%的产率得到10-methoxydibenzo[c,g]phenanthrene
  参考文献：
  名称：

  Synthesis of [5]Helicenes with a Substituent Exclusively on the Interior Side of the Helix by Metal-catalyzed Cycloisomerization

  摘要：

  [5]Helicenes with a substituent exclusively oriented toward the interior curvature of the helix are synthesized by metal-catalyzed cycloisomerization. In addition, novel azulene-fused helicenes have been found through cycloisomerization studies. These [5]helicenes shows a high enough configurationally stability to allow resolution by HPLC on a chiral stationary phase.

  DOI：

  10.1021/ol400332j

文献信息

• Synthesis of [5]Helicenes with a Substituent Exclusively on the Interior Side of the Helix by Metal-catalyzed Cycloisomerization
  作者：Kosuke Yamamoto、Mieko Okazumi、Hiroshi Suemune、Kazuteru Usui

  DOI：10.1021/ol400332j

  日期：2013.4.19

  [5]Helicenes with a substituent exclusively oriented toward the interior curvature of the helix are synthesized by metal-catalyzed cycloisomerization. In addition, novel azulene-fused helicenes have been found through cycloisomerization studies. These [5]helicenes shows a high enough configurationally stability to allow resolution by HPLC on a chiral stationary phase.