6,6,7,7-tetrafluoro-4-oxaheptan-1,2-diol | 25385-68-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 甘油脂
• 英文名称: 6,6,7,7-tetrafluoro-4-oxaheptan-1,2-diol
• 英文别名: 3-(2,2,3,3-Tetrafluoropropoxy)propane-1,2-diol
• CAS: 25385-68-6
• 化学式: C₆H₁₀F₄O₃
• 分子量: 206.137
• InChiKey: LCNPYINHENVWOH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.3
• 重原子数：
  13
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  49.7
• 氢给体数：
  2
• 氢受体数：
  7

安全信息

• 海关编码：
  2909499000

反应信息

• 作为反应物：
  描述：

  6,6,7,7-tetrafluoro-4-oxaheptan-1,2-diol 、 甲基丙烯酰氯 在 吡啶 、 diphenyl picryl hydrazyl 作用下， 以 乙醚 为溶剂， 以11%的产率得到2-Methyl-acrylic acid 1-(2-methyl-acryloyloxymethyl)-2-(2,2,3,3-tetrafluoro-propoxy)-ethyl ester
  参考文献：
  名称：

  Fluoroalkyl derivatives of protected glycerol by nucleophilic substitution. Fluorine-containing amphiphilic mono- and bis-methacrylates

  摘要：

  The tosylate of protected glycerol (solketal, 4-(hydroxymethyl)-2,2-dimethyl-1,3-dioxolane) was fluoroalkylated by a nucleophilic substitution reaction with sodium polyfluoroalkoxides. On deprotection, 3-O-fluoroalkylated glycerol was obtained which was converted to mono-and bis-methacrylates; analogous methacrylate derivatives were prepared from 3,3,4,5,5,5-hexafluoro-pentane-1,2-diol. (C) 1997 Elsevier Science S.A.

  DOI：

  10.1016/s0022-1139(97)00063-8
• 作为产物：
  描述：

  3-(2,2,3,3-四氟丙氧基)-1,2-氧化丙烯 在 sodium hydroxide 、 四丁基碘化铵 、 异丙醇 作用下， 以 二氯甲烷 、 水 为溶剂， 反应 4.0h， 以42%的产率得到6,6,7,7-tetrafluoro-4-oxaheptan-1,2-diol
  参考文献：
  名称：

  碱性介质中含氟缩水甘油醚与醇反应的特征

  摘要：

  The reaction of fluorine-containing glycidyl ethers with various alcohols (i-PrOH, MeOH, PhOH, 2,2,3,3-tetrafluoropropanol) in basic medium resulted in products of regioselective opening of the oxirane ring. In reaction of 2,2,3,3-tetrafluoropropyloxymethyloxirane with 2-propanol under conditions of phase-transfer catalysis the main product was the corresponding 1,2-diol (yield 42%).

  DOI：

  10.1134/s1070428007050041

文献信息

• [EN] EPOXY RESIN SYSTEM USED FOR PULTRUSION MOLDING AND COMPOSITE MATERIAL PREPARED THEREBY<br/>[FR] SYSTÈME DE RÉSINE ÉPOXY UTILISÉ POUR LE MOULAGE PAR PULTRUSION ET MATÉRIAU COMPOSITE AINSI PRÉPARÉ<br/>[ZH] 拉挤成型用环氧树脂体系及其制备的复合材料
  申请人：JIANGSU AOSHENG COMPOSITE MAT HI TECH COMPANY LIMITED

  公开号：WO2020019546A1

  公开（公告）日：2020-01-30

  一种拉挤成型用环氧树脂体系，包含以下组分：环氧树脂100重量份；异氰酸酯类固化剂30～60重量份；含氟环氧化合物2～10重量份。还含有胺类固化剂30～60重量份，氟硅聚合物1～10重量份，促进剂1～10重量份。还提供一种环氧树脂复合材料，根据上述拉挤成型用环氧树脂体系制备而成。上述拉挤成型用环氧树脂体系具有更高的固化速率，用于拉挤成型工艺中可以大大提高牵引速度，从而提高工作效率。同时制备得到的环氧树脂制品力学性能优异，韧性好。
• Features of reaction between fluorine-containing glycidyl ethers and alcohols in basic medium
  作者：D. N. Bazhin、T. I. Gorbunova、A. Ya. Zapevalov、V. E. Kirichenko、V. I. Saloutin

  DOI：10.1134/s1070428007050041

  日期：2007.5

  The reaction of fluorine-containing glycidyl ethers with various alcohols (i-PrOH, MeOH, PhOH, 2,2,3,3-tetrafluoropropanol) in basic medium resulted in products of regioselective opening of the oxirane ring. In reaction of 2,2,3,3-tetrafluoropropyloxymethyloxirane with 2-propanol under conditions of phase-transfer catalysis the main product was the corresponding 1,2-diol (yield 42%).
• Fluoroalkyl derivatives of protected glycerol by nucleophilic substitution. Fluorine-containing amphiphilic mono- and bis-methacrylates
  作者：Jaroslav Kvíčala、Bohumil Dolenský、Oldřich Paleta

  DOI：10.1016/s0022-1139(97)00063-8

  日期：1997.10

  The tosylate of protected glycerol (solketal, 4-(hydroxymethyl)-2,2-dimethyl-1,3-dioxolane) was fluoroalkylated by a nucleophilic substitution reaction with sodium polyfluoroalkoxides. On deprotection, 3-O-fluoroalkylated glycerol was obtained which was converted to mono-and bis-methacrylates; analogous methacrylate derivatives were prepared from 3,3,4,5,5,5-hexafluoro-pentane-1,2-diol. (C) 1997 Elsevier Science S.A.