1,3-Dicyclohexyl-5-benzyl-barbitursaeure | 16357-96-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: 1,3-Dicyclohexyl-5-benzyl-barbitursaeure
• 英文别名: 5-Benzyl-1,3-dicyclohexyl-1,3-diazinane-2,4,6-trione
• CAS: 16357-96-3
• 化学式: C₂₃H₃₀N₂O₃
• 分子量: 382.503
• InChiKey: UGTKBKBXFRUKHM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.8
• 重原子数：
  28
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.61
• 拓扑面积：
  57.7
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  苯甲醇 、 1,3-二环己基巴比妥酸 在 (1,4-dimethyl-5,7-diphenyl-1,2,3,4-tetrahydro-6H-cyclopenta[b]pyrazin-6-one) irontricarbonyl complex3 、 三苯基膦 作用下， 以 5,5-dimethyl-1,3-cyclohexadiene 为溶剂， 反应 24.0h， 以75%的产率得到1,3-Dicyclohexyl-5-benzyl-barbitursaeure
  参考文献：
  名称：

  铁催化的吲哚与醇的借位氢C-烷基化

  摘要：

  已经开发了一种普遍有效的铁催化的吲哚的C烷基化反应。使用（环戊二烯酮）羰基铁络合物（2mol％）的这种借入氢方法表现出广泛的反应范围，允许将苄基和简单的伯和仲脂肪族醇用作烷基化剂。各种羟吲哚以良好的分离效率进行了选择性的单C 3-烷基化反应（28个实例，50-92％的产率，79％的平均产率）。

  DOI：

  10.1002/cssc.201900799

文献信息

• POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND DISPLAY DEVICE
  申请人：FUJIFILM Corporation

  公开号：US20170226317A1

  公开（公告）日：2017-08-10

  A polarizing plate protective film which prevents deterioration of polarization performance in a high temperature, high humidity environment, and a polarizing plate and display device using the film including a compound represented by the following General Formula (I). (X-L n z General Formula (I) X represents a formyl group, a boronic acid group, or a group represented by the following General Formula (I-B) or a group represented by the following General Formula (I-C), where L represents a single bond or divalent linking group, and n represents an integer equal to or greater than 2. When n is 2, Z represents a single bond or a divalent group, and when n≧3, Z represents an n-valent group. R A and R B represent an alkyl group, a cycloalkyl group, an aryl group, or an acyl group. R A and R B may be bonded to each other to form a ring. * represents a bond to be bonded to L.

  一种偏光板保护膜，可防止在高温高湿环境中偏光性能的恶化，以及使用包括下述一般式（I）所代表的化合物的偏光板和显示装置。 （X-L n z 一般式（I） X代表甲酰基、硼酸基或由下述一般式（I-B）所代表的基团或由下述一般式（I-C）所代表的基团，其中L代表单键或二价连接基团，n代表大于或等于2的整数。当n为2时，Z代表单键或二价基团，当n≧3时，Z代表n价基团。 RA和RB代表烷基、环烷基、芳基或酰基。RA和RB可以相互连接形成环。*代表要连接到L的键。
• Ruthenium-catalyzed selective synthesis of monoalkylated barbituric acids through “borrowing hydrogen” methodology
  作者：Anggi Eka Putra、Yohei Oe、Tetsuo Ohta

  DOI：10.1016/j.tetlet.2017.01.070

  日期：2017.3

  An environmentally benign alkylation of barbituric acids via “borrowing hydrogen” process with ruthenium catalysis has been established. The corresponding 5-(alkyl)barubituric acids were obtained in good to excellent yields with low catalyst loading. Various substrates including aliphatic alcohols were tolerated in the present catalytic system. A novel method for construction of barbituric acid-fused

  已经建立了通过“借入氢”过程和钌催化对巴比妥酸进行无害环境的烷基化反应。以良好的至优异的产率和较低的催化剂负载量获得了相应的5-（烷基）Barubituric酸。在本催化体系中，包括脂肪族醇在内的各种底物是可以容忍的。还证明了一种新的构建巴比妥酸稠合的苯并吡喃衍生物的方法。
• CELLULOSE ACYLATE FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY USING THE SAME
  申请人：FUJIFILM Corporation

  公开号：US20160124123A1

  公开（公告）日：2016-05-05

  A cellulose acylate film, containing at least: a cellulose acylate; and a compound represented by the following Formula (I): wherein R 1 , R 3 and R 5 each independently designate a hydrogen atom, an alkyl group, a cycloalkyl group, an alkenyl group, or an aromatic group, which groups may have a further substituent; with the proviso that at least one of R 1 , R 3 and R 5 is an alkyl group substituted with a group having a ring structure or a cycloalkyl group, and the total number of the ring structures existing in R 1 , R 3 and R 5 is 3 or more.

  一种纤维素酰基膜，至少包含以下成分：纤维素酰基；以及下式（I）所表示的化合物：其中R1、R3和R5各自独立地表示氢原子、烷基、环烷基、烯基或芳基，这些基团可能具有进一步的取代基；但至少其中之一的R1、R3和R5是取代有环结构的烷基或环烷基，且存在于R1、R3和R5中的环结构总数为3个或更多。
• Optical film and method for manufacturing same, polarization plate, and liquid crystal display apparatus
  申请人：FUJIFILM Corporation

  公开号：US10240033B2

  公开（公告）日：2019-03-26

  The optical film of the present invention is an optical film including a thermoplastic resin, in which the optical film has a moisture permeability of 70 g/m2/day or less (in terms of a film thickness of 40 μm), and contains a moisture permeability-reducing compound having a molecular weight of 200 or more and satisfying Formula (1) described below. Formula (1) A/B≤0.9 (A represents a moisture permeability of an optical film in a case in which 10 mass % of the moisture permeability-reducing compound is added to the mass of the thermoplastic resin, and B represents a moisture permeability of an optical film in a case in which the thermoplastic resin is included and the moisture permeability-reducing compound is not added.)

  本发明的光学薄膜是一种包括热塑性树脂的光学薄膜，其中光学薄膜的透湿性为 70 克/平方米/天以下（以薄膜厚度为 40 微米计），并含有分子量为 200 以上且满足下述式（1）的透湿性降低化合物。式（1）A/B≤0.9（A 表示在热塑性树脂的质量中添加 10 质量％的透湿性降低化合物时光学薄膜的透湿性，B 表示包含热塑性树脂且不添加透湿性降低化合物时光学薄膜的透湿性）。
• Hardcoat film, polarizing plate, liquid crystal display, and method for manufacturing hardcoat film
  申请人：FUJIFILM Corporation

  公开号：US10365411B2

  公开（公告）日：2019-07-30

  A hardcoat film including a support and a hardcoat layer, in which the support contains a resin as a main component, a film thickness of the hardcoat layer exceeds 20 μm, the hardcoat layer contains a structure derived from a compound which has one alicyclic epoxy group and one ethylenically unsaturated double bond group and has a molecular weight equal to or less than 300, and a structure derived from a compound which has 3 or more ethylenically unsaturated double bond groups, a radical polymerization initiator and a cationic polymerization initiator.

  一种硬涂层薄膜，包括支撑体和硬涂层，其中支撑体包含作为主要成分的树脂，硬涂层的膜厚超过 20 μm，硬涂层包含一种由具有一个脂环族环氧基团和一个乙烯基不饱和双键基团且分子量等于或小于 300 的化合物衍生的结构，以及一种由具有 3 个或更多乙烯基不饱和双键基团的化合物衍生的结构、一种自由基聚合引发剂和一种阳离子聚合引发剂。