Sodium; 10-fluoro-decanoate | 63977-34-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: Sodium; 10-fluoro-decanoate
• 英文别名: Decanoic acid, 10-fluoro-, sodium salt；sodium;10-fluorodecanoate
• CAS: 63977-34-4
• 化学式: C₁₀H₁₈FO₂*Na
• 分子量: 212.24
• InChiKey: RXYIFNCNTGFNBO-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -1.17
• 重原子数：
  14
• 可旋转键数：
  9
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  40.1
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  10-羟基癸酸甲酯 在 二乙胺基三氟化硫 作用下， 生成 Sodium; 10-fluoro-decanoate
  参考文献：
  名称：

  Evidence for an octanoate synthase operating during the biosynthesis of piliformic acid in Poronia piliformis

  摘要：

  Sodium [1-C-13]-octanoate is incorporated intact into the C-8 unit of piliformic acid 1 in Poronia piliformis whereas sodium [3-C-13]-decanoate 2 is incorporated into this unit only after prior beta-oxidation to [1-C-13]-acetyl-CoA. Also 8-fluoraoctanaote 3 is utilised by P. piliformis as an intact unit to generate 9-fluoropiliformic acid 5 whereas 10-fluorodecanoate 4 is not. These results suggest that octanoate is biosynthesised de novo for secondary metabolism and is not assimilated from higher fatty acids by beta-oxidation. (C) 1998 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(98)00102-6

文献信息

• Evidence for an octanoate synthase operating during the biosynthesis of piliformic acid in Poronia piliformis
  作者：Helen Culceth、Jens Fuchser、Steven J Moss、Jens Nieschalk、David O'Hagan

  DOI：10.1016/s0040-4039(98)00102-6

  日期：1998.4

  Sodium [1-C-13]-octanoate is incorporated intact into the C-8 unit of piliformic acid 1 in Poronia piliformis whereas sodium [3-C-13]-decanoate 2 is incorporated into this unit only after prior beta-oxidation to [1-C-13]-acetyl-CoA. Also 8-fluoraoctanaote 3 is utilised by P. piliformis as an intact unit to generate 9-fluoropiliformic acid 5 whereas 10-fluorodecanoate 4 is not. These results suggest that octanoate is biosynthesised de novo for secondary metabolism and is not assimilated from higher fatty acids by beta-oxidation. (C) 1998 Elsevier Science Ltd. All rights reserved.