crotonal phenylhydrazone | 54059-73-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: crotonal phenylhydrazone
• 英文别名: crotonaldehyde phenylhydrazone；Crotonaldehyd-phenylhydrazon；Crotonaldehydphenylhydrazon；N-[(E)-[(E)-but-2-enylidene]amino]aniline
• CAS: 54059-73-3；63452-51-7
• 化学式: C₁₀H₁₂N₂
• 分子量: 160.219
• InChiKey: IOFSAEUSDMVHTR-QDWNBNDKSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  24.4
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  crotonal phenylhydrazone 在 palladium on activated charcoal 盐酸羟胺 、 氢气 、 sodium acetate 作用下， 以 乙醇 、 苯 为溶剂， 反应 5.5h， 生成 N-Phenyl-N'-1,3-diaminobutylhydrazine
  参考文献：
  名称：

  Siddiqui, Amin A.; Khan, Naseem H.; Basheeruddin, Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1981, vol. 20, # 11, p. 1003 - 1005

  摘要：

  DOI：
• 作为产物：
  描述：

  苯肼 、 丁烯-2-醛 在 乙醇 作用下， 生成 crotonal phenylhydrazone
  参考文献：
  名称：

  Defaecation syncope and pulmonary thromboembolism in a cat

  摘要：

  A 7‐year‐old male neutered domestic shorthair cat was referred for worsening gastrointestinal and haematologic abnormalities. Physical status deteriorated further despite intravenous crystalloids, blood transfusion and nutritional support. Cardiorespiratory signs developed and the cat died suddenly while straining to defaecate. Diffuse thrombosis, pulmonary thromboembolism, metastatic pancreatic carcinoma and histologic evidence of cardiomyopathy were present at necropsy. This is the first reported case of feline pulmonary thromboembolism associated with defaecation syncope. Predisposing factors for thrombotic disease in this case and aspects of human defaecation syncope are discussed. The risk of clot dislodgement by the Valsalva manoeuvre in patients with a thrombotic tendency is highlighted.

  DOI：

  10.1111/j.1751-0813.2001.tb12982.x

文献信息

• v. Auwers; Kreuder, Chemische Berichte, 1925, vol. 58, p. 1981
  作者：v. Auwers、Kreuder

  DOI：——

  日期：——
• v.Auwers; Broche, Chemische Berichte, 1922, vol. 55, p. 3907
  作者：v.Auwers、Broche

  DOI：——

  日期：——
• SIDDIQUI, A. A.;KHAN, N. H.;BASHEERUDDIN, INDIAN J. CHEM., 1981, 20, N 11, 1003-1005
  作者：SIDDIQUI, A. A.、KHAN, N. H.、BASHEERUDDIN

  DOI：——

  日期：——
• Defaecation syncope and pulmonary thromboembolism in a cat
  作者：NT WHITLEY、RL STEPIEN

  DOI：10.1111/j.1751-0813.2001.tb12982.x

  日期：2001.6

  A 7‐year‐old male neutered domestic shorthair cat was referred for worsening gastrointestinal and haematologic abnormalities. Physical status deteriorated further despite intravenous crystalloids, blood transfusion and nutritional support. Cardiorespiratory signs developed and the cat died suddenly while straining to defaecate. Diffuse thrombosis, pulmonary thromboembolism, metastatic pancreatic carcinoma and histologic evidence of cardiomyopathy were present at necropsy. This is the first reported case of feline pulmonary thromboembolism associated with defaecation syncope. Predisposing factors for thrombotic disease in this case and aspects of human defaecation syncope are discussed. The risk of clot dislodgement by the Valsalva manoeuvre in patients with a thrombotic tendency is highlighted.
• Siddiqui, Amin A.; Khan, Naseem H.; Basheeruddin, Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1981, vol. 20, # 11, p. 1003 - 1005
  作者：Siddiqui, Amin A.、Khan, Naseem H.、Basheeruddin

  DOI：——

  日期：——